ZENTALIS PHARMACEUTICALS INC (ZNTL) Institutional Shareholders
ZENTALIS PHARMACEUTICALS INC (ZNTL) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $228.13M in ZNTL holdings during the latest filing period.
5Am Venture Management, Llc is currently the largest disclosed institutional shareholder of ZNTL tracked by InsiderSet, reporting ownership valued at approximately $19.15M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $12.28M, representing an estimated loss of -35.88% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 57% of the total disclosed ZNTL value among the investors covered in this analysis. Major shareholders include 5Am Venture Management, Llc, Blackrock, Inc., Squadron Capital Management Llc, and several other long-term asset managers with concentrated positions in ZENTALIS PHARMACEUTICALS INC (ZNTL).
This page ranks the largest institutional ZNTL shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
113
Total Reported Value
$228.13M
Largest Holder
5Am Venture Management, Llc
Largest Position
$19.15M
Insider Transactions (90d)
1
Latest Filing Quarter
Q2 2026
New Institutional Positions
145
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| 5Am Venture Management, Llc | 6.65% | 3,947,913 | $19,147,378 | $12,278,009 | -$6,869,369 | -35.88% | |
| Blackrock, Inc. | 0.00% | 3,753,525 | $18,204,597 | $11,673,463 | -$6,531,134 | -35.88% | |
| Squadron Capital Management Llc | 6.14% | 3,700,000 | $17,945,000 | $11,507,000 | -$6,438,000 | -35.88% | |
| Two Sigma Investments, Lp | 0.01% | 3,024,936 | $14,670,940 | $9,407,551 | -$5,263,389 | -35.88% | |
| Vanguard Capital Management Llc | 0.00% | 2,835,669 | $13,752,995 | $8,818,931 | -$4,934,064 | -35.88% | |
| Acadian Asset Management Llc | 0.02% | 2,681,900 | $12,995,000 | $8,340,709 | -$4,654,291 | -35.82% | |
| Citadel Advisors Llc | 0.01% | 2,298,403 | $11,147,254 | $7,148,033 | -$3,999,221 | -35.88% | |
| Renaissance Technologies LLC | Jim Simons | 0.01% | 1,609,078 | $7,804,028 | $5,004,233 | -$2,799,795 | -35.88% |
| Opaleye Management Inc. | 0.62% | 1,412,656 | $6,851,382 | $4,393,360 | -$2,458,022 | -35.88% | |
| Orbimed Advisors Llc | 0.13% | 1,390,576 | $6,744,294 | $4,324,691 | -$2,419,603 | -35.88% | |
| Decheng Capital Llc | 0.88% | 1,323,327 | $6,418,136 | $4,115,547 | -$2,302,589 | -35.88% | |
| Geode Capital Management, Llc | 0.00% | 1,284,117 | $6,229,699 | $3,993,604 | -$2,236,095 | -35.89% | |
| Bank Of America Corp | 0.00% | 1,114,650 | $5,406,053 | $3,466,562 | -$1,939,492 | -35.88% | |
| Ishara Investments Lp | 3.65% | 1,025,000 | $4,971,250 | $3,187,750 | -$1,783,500 | -35.88% | |
| Primecap Management Co/Ca/ | 0.00% | 957,420 | $4,643,487 | $2,977,576 | -$1,665,911 | -35.88% | |
| Soleus Capital Management, L.P. | 0.16% | 950,000 | $4,607,500 | $2,954,500 | -$1,653,000 | -35.88% | |
| State Street Corp | 0.00% | 887,416 | $4,303,968 | $2,759,864 | -$1,544,104 | -35.88% | |
| Vanguard Portfolio Management Llc | 0.00% | 808,548 | $3,921,458 | $2,514,584 | -$1,406,874 | -35.88% | |
| Pfizer Inc | 2.26% | 953,834 | $3,853,489 | $2,966,424 | -$887,065 | -23.02% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | 758,033 | $3,676,460 | $2,357,483 | -$1,318,977 | -35.88% | |
| Millennium Management Llc | 0.00% | 664,281 | $3,221,763 | $2,065,914 | -$1,155,849 | -35.88% | |
| Adar1 Capital Management, Llc | 0.15% | 652,750 | $3,165,838 | $2,030,053 | -$1,135,786 | -35.88% | |
| Marshall Wace, Llp | 0.00% | 591,473 | $2,868,644 | $1,839,481 | -$1,029,163 | -35.88% | |
| Qube Research & Technologies Ltd | 0.00% | 574,806 | $2,787,809 | $1,787,647 | -$1,000,162 | -35.88% | |
| D. E. Shaw & Co., Inc. | 0.00% | 546,566 | $2,650,845 | $1,699,820 | -$951,025 | -35.88% | |
| Dimensional Fund Advisors Lp | 0.00% | 542,852 | $2,630,116 | $1,688,270 | -$941,846 | -35.81% | |
| Morgan Stanley | 0.00% | 471,250 | $2,285,563 | $1,465,588 | -$819,976 | -35.88% | |
| Northern Trust Corp | 0.00% | 388,299 | $1,883,251 | $1,207,610 | -$675,641 | -35.88% | |
| Gsa Capital Partners Llp | 0.11% | 374,260 | $1,815,000 | $1,163,949 | -$651,051 | -35.87% | |
| Goldman Sachs Group Inc | 0.00% | 372,564 | $1,806,936 | $1,158,674 | -$648,262 | -35.88% | |
| Vanguard Fiduciary Trust Co | 0.00% | 336,940 | $1,634,159 | $1,047,883 | -$586,276 | -35.88% | |
| Fmr Llc | 0.00% | 310,264 | $1,504,780 | $964,921 | -$539,859 | -35.88% | |
| Seven Fleet Capital Management Lp | 0.24% | 317,600 | $1,451,432 | $987,736 | -$463,696 | -31.95% | |
| Ubs Group Ag | 0.00% | 297,378 | $1,442,283 | $924,846 | -$517,437 | -35.88% | |
| Xtx Topco Ltd | 0.02% | 289,693 | $1,405,011 | $900,945 | -$504,066 | -35.88% | |
| Sei Investments Co | 0.00% | 256,079 | $1,241,983 | $796,406 | -$445,577 | -35.88% | |
| Susquehanna International Group, Llp | 0.00% | 215,113 | $1,043,298 | $669,001 | -$374,297 | -35.88% | |
| Peapod Lane Capital Llc | 0.66% | 202,864 | $983,890 | $630,907 | -$352,983 | -35.88% | |
| Cdc Financial, Inc. | 0.66% | 177,762 | $862,146 | $552,840 | -$309,306 | -35.88% | |
| Charles Schwab Investment Management Inc | 0.00% | 171,911 | $833,768 | $534,643 | -$299,125 | -35.88% | |
| Invesco Ltd. | 0.00% | 161,657 | $784,037 | $502,753 | -$281,284 | -35.88% | |
| Stonepine Capital Management, Llc | 0.60% | 161,583 | $783,678 | $502,523 | -$281,155 | -35.88% | |
| Barclays Plc | 0.00% | 158,856 | $770,452 | $494,042 | -$276,410 | -35.88% | |
| Anfield Capital Management, Llc | 0.18% | 274,516 | $642,367 | $853,745 | +$211,378 | +32.91% | |
| Informed Momentum Co Llc | 0.05% | 126,863 | $615,286 | $394,544 | -$220,742 | -35.88% | |
| Quarry Lp | 0.10% | 125,114 | $606,803 | $389,105 | -$217,698 | -35.88% | |
| Bank Of New York Mellon Corp | 0.00% | 122,068 | $592,030 | $379,631 | -$212,399 | -35.88% | |
| Susquehanna Portfolio Strategies, Llc | 0.01% | 112,122 | $543,792 | $348,699 | -$195,093 | -35.88% | |
| Barr E S & Co | 0.03% | 110,000 | $533,500 | $342,100 | -$191,400 | -35.88% | |
| Federated Hermes, Inc. | 0.00% | 98,617 | $478,292 | $306,699 | -$171,593 | -35.88% |
Frequently asked questions about ZNTL
Who owns the most ZNTL stock?
The largest holders of ZNTL are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ZENTALIS PHARMACEUTICALS INC (ZNTL).
Is ZNTL widely held by superinvestors?
Many widely followed stocks like ZNTL appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ZNTL is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.