ZENTALIS PHARMACEUTICALS INC (ZNTL) Top Institutional Shareholders
ZENTALIS PHARMACEUTICALS INC (ZNTL) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $93.26M in ZNTL holdings during the latest filing period.
5Am Venture Management, Llc is currently the largest disclosed institutional shareholder of ZNTL tracked by InsiderSet, reporting ownership valued at approximately $9.24M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $14.29M, representing an estimated gain of +54.70% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 55% of the total disclosed ZNTL value among the investors covered in this analysis. Major shareholders include 5Am Venture Management, Llc, Squadron Capital Management Llc, Two Sigma Investments, Lp, and several other long-term asset managers with concentrated positions in ZENTALIS PHARMACEUTICALS INC (ZNTL).
This page ranks the largest institutional ZNTL shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
99
Total Reported Value
$93.26M
Largest Holder
5Am Venture Management, Llc
Largest Position
$9.24M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
112
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| 5Am Venture Management, Llc | 2.56% | 3,947,913 | $9,238,116 | $14,291,445 | +$5,053,329 | +54.70% | |
| Squadron Capital Management Llc | 3.40% | 3,631,000 | $8,496,540 | $13,144,220 | +$4,647,680 | +54.70% | |
| Two Sigma Investments, Lp | 0.01% | 2,956,526 | $6,918,271 | $10,702,624 | +$3,784,353 | +54.70% | |
| Vanguard Capital Management Llc | 0.00% | 2,310,707 | $5,407,054 | $8,364,759 | +$2,957,705 | +54.70% | |
| Renaissance Technologies LLC | Jim Simons | 0.01% | 1,938,145 | $4,535,259 | $7,016,085 | +$2,480,826 | +54.70% |
| Citadel Advisors Llc | 0.00% | 1,732,083 | $4,053,074 | $6,270,140 | +$2,217,066 | +54.70% | |
| D. E. Shaw & Co., Inc. | 0.00% | 1,484,098 | $3,472,789 | $5,372,435 | +$1,899,646 | +54.70% | |
| Opaleye Management Inc. | 0.44% | 1,412,656 | $3,305,615 | $5,113,815 | +$1,808,200 | +54.70% | |
| Decheng Capital Llc | 0.47% | 1,323,327 | $3,096,585 | $4,790,444 | +$1,693,859 | +54.70% | |
| Millennium Management Llc | 0.00% | 1,289,822 | $3,018,183 | $4,669,156 | +$1,650,973 | +54.70% | |
| Blackrock, Inc. | 0.00% | 1,269,837 | $2,971,419 | $4,596,810 | +$1,625,391 | +54.70% | |
| Ishara Investments Lp | 2.91% | 1,230,000 | $2,878,200 | $4,452,600 | +$1,574,400 | +54.70% | |
| Bank Of America Corp | 0.00% | 1,132,294 | $2,649,568 | $4,098,904 | +$1,449,336 | +54.70% | |
| Primecap Management Co/Ca/ | 0.00% | 957,420 | $2,240,363 | $3,465,860 | +$1,225,497 | +54.70% | |
| Pfizer Inc | 0.84% | 953,834 | $2,003,051 | $3,452,879 | +$1,449,828 | +72.38% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | 792,001 | $1,853,282 | $2,867,044 | +$1,013,762 | +54.70% | |
| Qube Research & Technologies Ltd | 0.00% | 637,116 | $1,490,851 | $2,306,360 | +$815,509 | +54.70% | |
| Geode Capital Management, Llc | 0.00% | 621,036 | $1,454,005 | $2,248,150 | +$794,145 | +54.62% | |
| Almitas Capital Llc | 0.32% | 610,073 | $1,427,571 | $2,208,464 | +$780,893 | +54.70% | |
| Barclays Plc | 0.00% | 591,217 | $1,383,448 | $2,140,206 | +$756,758 | +54.70% | |
| Susquehanna International Group, Llp | 0.00% | 571,257 | $1,336,741 | $2,067,950 | +$731,209 | +54.70% | |
| Jane Street Group, Llc | 0.00% | 490,339 | $1,147,393 | $1,775,027 | +$627,634 | +54.70% | |
| Bnp Paribas Financial Markets | 0.00% | 471,438 | $1,103,165 | $1,706,606 | +$603,441 | +54.70% | |
| Goldman Sachs Group Inc | 0.00% | 462,678 | $1,082,666 | $1,674,894 | +$592,228 | +54.70% | |
| Marshall Wace, Llp | 0.00% | 392,643 | $918,785 | $1,421,368 | +$502,583 | +54.70% | |
| Vanguard Portfolio Management Llc | 0.00% | 360,600 | $843,804 | $1,305,372 | +$461,568 | +54.70% | |
| Peapod Lane Capital Llc | 0.68% | 366,868 | $834,581 | $1,328,062 | +$493,481 | +59.13% | |
| Morgan Stanley | 0.00% | 350,207 | $819,483 | $1,267,749 | +$448,266 | +54.70% | |
| Xtx Topco Ltd | 0.01% | 322,507 | $754,666 | $1,167,475 | +$412,809 | +54.70% | |
| Vanguard Fiduciary Trust Co | 0.00% | 304,471 | $712,462 | $1,102,185 | +$389,723 | +54.70% | |
| Creative Planning | 0.00% | 285,000 | $666,900 | $1,031,700 | +$364,800 | +54.70% | |
| Fmr Llc | 0.00% | 283,917 | $664,366 | $1,027,780 | +$363,414 | +54.70% | |
| Cdc Financial, Inc. | 0.55% | 283,762 | $664,003 | $1,027,218 | +$363,215 | +54.70% | |
| Anfield Capital Management, Llc | 0.18% | 274,516 | $642,367 | $993,748 | +$351,381 | +54.70% | |
| Dimensional Fund Advisors Lp | 0.00% | 272,034 | $634,296 | $984,763 | +$350,467 | +55.25% | |
| Stonepine Capital Management, Llc | 0.56% | 269,100 | $629,694 | $974,142 | +$344,448 | +54.70% | |
| Woodline Partners Lp | 0.00% | 266,032 | $622,515 | $963,036 | +$340,521 | +54.70% | |
| State Street Corp | 0.00% | 249,690 | $584,275 | $903,878 | +$319,603 | +54.70% | |
| Sei Investments Co | 0.00% | 191,551 | $448,229 | $693,415 | +$245,186 | +54.70% | |
| Ubs Group Ag | 0.00% | 155,704 | $364,348 | $563,648 | +$199,300 | +54.70% | |
| Quarry Lp | 0.07% | 150,000 | $351,000 | $543,000 | +$192,000 | +54.70% | |
| Adar1 Capital Management, Llc | 0.02% | 144,636 | $338,448 | $523,582 | +$185,134 | +54.70% | |
| Panagora Asset Management Inc | 0.00% | 139,690 | $326,875 | $505,678 | +$178,803 | +54.70% | |
| Invesco Ltd. | 0.00% | 125,767 | $294,295 | $455,277 | +$160,982 | +54.70% | |
| Northern Trust Corp | 0.00% | 118,186 | $276,555 | $427,833 | +$151,278 | +54.70% | |
| Hudson Bay Capital Management Lp | 0.00% | 117,127 | $274,077 | $424,000 | +$149,923 | +54.70% | |
| Barr E S & Co | 0.01% | 110,000 | $257,400 | $398,200 | +$140,800 | +54.70% | |
| Seven Fleet Capital Management Lp | 0.08% | 110,000 | $257,400 | $398,200 | +$140,800 | +54.70% | |
| Simplex Trading, Llc | 0.01% | 98,554 | $230,616 | $356,765 | +$126,149 | +54.70% | |
| Point72 Asset Management, L.P. | 0.00% | 94,854 | $221,958 | $343,371 | +$121,413 | +54.70% |
Frequently asked questions about ZNTL
Who owns the most ZNTL stock?
The largest holders of ZNTL are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ZENTALIS PHARMACEUTICALS INC (ZNTL).
Is ZNTL widely held by superinvestors?
Many widely followed stocks like ZNTL appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ZNTL is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.