ZNTL Institutional Ownership & Shareholders
ZENTALIS PHARMACEUTICALS INC (ZNTL) is currently held by 117 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $227.45M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
5Am Venture Management, Llc is currently the largest disclosed institutional shareholder of ZNTL tracked by InsiderSet, reporting ownership valued at approximately $19.15M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $7.30M, representing an estimated loss of -61.86% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 57% of the total disclosed ZNTL value among the investors covered in this analysis. Major shareholders include 5Am Venture Management, Llc, Blackrock, Inc., Squadron Capital Management Llc, and several other long-term asset managers with concentrated positions in ZENTALIS PHARMACEUTICALS INC (ZNTL).
This page ranks the largest institutional ZNTL shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
117
Total Reported Value
$227.45M
Largest Holder
5Am Venture Management, Llc
Largest Position
$19.15M
Insider Transactions (90d)
2
Latest Filing Quarter
Q2 2026
New Institutional Positions
151
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| 5Am Venture Management, Llc | 6.65% | 3,947,913 | $19,147,378 | $7,303,639 | -$11,843,739 | -61.86% | |
| Blackrock, Inc. | 0.00% | 3,753,525 | $18,204,597 | $6,944,021 | -$11,260,576 | -61.86% | |
| Squadron Capital Management Llc | 6.14% | 3,700,000 | $17,945,000 | $6,845,000 | -$11,100,000 | -61.86% | |
| Two Sigma Investments, Lp | 0.01% | 3,024,936 | $14,670,940 | $5,596,132 | -$9,074,808 | -61.86% | |
| Vanguard Capital Management Llc | 0.00% | 2,835,669 | $13,752,995 | $5,245,988 | -$8,507,007 | -61.86% | |
| Acadian Asset Management Llc | 0.02% | 2,681,900 | $12,995,000 | $4,961,515 | -$8,033,485 | -61.82% | |
| Citadel Advisors Llc | 0.01% | 2,298,403 | $11,147,254 | $4,252,046 | -$6,895,208 | -61.86% | |
| Renaissance Technologies LLC | Jim Simons | 0.01% | 1,609,078 | $7,804,028 | $2,976,794 | -$4,827,234 | -61.86% |
| Opaleye Management Inc. | 0.62% | 1,412,656 | $6,851,382 | $2,613,414 | -$4,237,968 | -61.86% | |
| Orbimed Advisors Llc | 0.13% | 1,390,576 | $6,744,294 | $2,572,566 | -$4,171,728 | -61.86% | |
| Decheng Capital Llc | 0.88% | 1,323,327 | $6,418,136 | $2,448,155 | -$3,969,981 | -61.86% | |
| Geode Capital Management, Llc | 0.00% | 1,284,117 | $6,229,699 | $2,375,616 | -$3,854,083 | -61.87% | |
| Bank Of America Corp | 0.00% | 1,114,650 | $5,406,053 | $2,062,103 | -$3,343,951 | -61.86% | |
| Ishara Investments Lp | 3.65% | 1,025,000 | $4,971,250 | $1,896,250 | -$3,075,000 | -61.86% | |
| Primecap Management Co/Ca/ | 0.00% | 957,420 | $4,643,487 | $1,771,227 | -$2,872,260 | -61.86% | |
| Soleus Capital Management, L.P. | 0.16% | 950,000 | $4,607,500 | $1,757,500 | -$2,850,000 | -61.86% | |
| State Street Corp | 0.00% | 887,416 | $4,303,968 | $1,641,720 | -$2,662,248 | -61.86% | |
| Vanguard Portfolio Management Llc | 0.00% | 808,548 | $3,921,458 | $1,495,814 | -$2,425,644 | -61.86% | |
| Pfizer Inc | 2.26% | 953,834 | $3,853,489 | $1,764,593 | -$2,088,896 | -54.21% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | 758,033 | $3,676,460 | $1,402,361 | -$2,274,099 | -61.86% | |
| Millennium Management Llc | 0.00% | 664,281 | $3,221,763 | $1,228,920 | -$1,992,843 | -61.86% | |
| Adar1 Capital Management, Llc | 0.15% | 652,750 | $3,165,838 | $1,207,588 | -$1,958,251 | -61.86% | |
| Marshall Wace, Llp | 0.00% | 591,473 | $2,868,644 | $1,094,225 | -$1,774,419 | -61.86% | |
| Qube Research & Technologies Ltd | 0.00% | 574,806 | $2,787,809 | $1,063,391 | -$1,724,418 | -61.86% | |
| D. E. Shaw & Co., Inc. | 0.00% | 546,566 | $2,650,845 | $1,011,147 | -$1,639,698 | -61.86% | |
| Dimensional Fund Advisors Lp | 0.00% | 542,852 | $2,630,116 | $1,004,276 | -$1,625,840 | -61.82% | |
| Morgan Stanley | 0.00% | 471,250 | $2,285,563 | $871,813 | -$1,413,751 | -61.86% | |
| Northern Trust Corp | 0.00% | 388,299 | $1,883,251 | $718,353 | -$1,164,898 | -61.86% | |
| Gsa Capital Partners Llp | 0.11% | 374,260 | $1,815,000 | $692,381 | -$1,122,619 | -61.85% | |
| Goldman Sachs Group Inc | 0.00% | 372,564 | $1,806,936 | $689,243 | -$1,117,693 | -61.86% | |
| Vanguard Fiduciary Trust Co | 0.00% | 336,940 | $1,634,159 | $623,339 | -$1,010,820 | -61.86% | |
| Fmr Llc | 0.00% | 310,264 | $1,504,780 | $573,988 | -$930,792 | -61.86% | |
| Seven Fleet Capital Management Lp | 0.24% | 317,600 | $1,451,432 | $587,560 | -$863,872 | -59.52% | |
| Ubs Group Ag | 0.00% | 297,378 | $1,442,283 | $550,149 | -$892,134 | -61.86% | |
| Xtx Topco Ltd | 0.02% | 289,693 | $1,405,011 | $535,932 | -$869,079 | -61.86% | |
| Sei Investments Co | 0.00% | 256,079 | $1,241,983 | $473,746 | -$768,237 | -61.86% | |
| Susquehanna International Group, Llp | 0.00% | 215,113 | $1,043,298 | $397,959 | -$645,339 | -61.86% | |
| Cdc Financial, Inc. | 0.66% | 177,762 | $862,146 | $328,860 | -$533,286 | -61.86% | |
| Creative Planning | 0.00% | 306,660 | $849,448 | $567,321 | -$282,127 | -33.21% | |
| Charles Schwab Investment Management Inc | 0.00% | 171,911 | $833,768 | $318,035 | -$515,733 | -61.86% | |
| Invesco Ltd. | 0.00% | 161,657 | $784,037 | $299,065 | -$484,972 | -61.86% | |
| Stonepine Capital Management, Llc | 0.60% | 161,583 | $783,678 | $298,929 | -$484,749 | -61.86% | |
| Barclays Plc | 0.00% | 158,856 | $770,452 | $293,884 | -$476,568 | -61.86% | |
| Anfield Capital Management, Llc | 0.18% | 274,516 | $642,367 | $507,855 | -$134,512 | -20.94% | |
| Informed Momentum Co Llc | 0.05% | 126,863 | $615,286 | $234,697 | -$380,589 | -61.86% | |
| Quarry Lp | 0.10% | 125,114 | $606,803 | $231,461 | -$375,342 | -61.86% | |
| Bank Of New York Mellon Corp | 0.00% | 122,068 | $592,030 | $225,826 | -$366,204 | -61.86% | |
| Susquehanna Portfolio Strategies, Llc | 0.01% | 112,122 | $543,792 | $207,426 | -$336,366 | -61.86% | |
| Barr E S & Co | 0.03% | 110,000 | $533,500 | $203,500 | -$330,000 | -61.86% | |
| Federated Hermes, Inc. | 0.00% | 98,617 | $478,292 | $182,441 | -$295,851 | -61.86% |
Frequently asked questions about ZNTL
Who are the largest institutional holders of ZNTL?
The largest institutional holders of ZNTL reported in the latest SEC Form 13F filings include 5Am Venture Management, Llc, Blackrock, Inc., Squadron Capital Management Llc, Two Sigma Investments, Lp, and Vanguard Capital Management Llc. InsiderSet ranks institutional holders by their latest reported ZNTL position.
What is ZNTL institutional ownership?
This page tracks ZNTL positions reported by institutional investment managers through SEC Form 13F. ZENTALIS PHARMACEUTICALS INC (ZNTL) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own ZNTL?
InsiderSet currently tracks 117 institutional managers reporting ZNTL holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of ZNTL shareholders.
How much ZNTL stock do institutions own?
Institutional investment managers disclosed approximately $227.45M in ZNTL holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was ZNTL institutional ownership last updated?
The latest ZNTL institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional ZNTL holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its ZNTL position after the reporting date.
Are institutions buying or selling ZNTL?
Institutional buying and selling can be analyzed by comparing ZNTL positions across consecutive 13F reporting periods. InsiderSet's ZNTL Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View ZNTL ownership changes.
How has ZNTL institutional ownership changed over time?
InsiderSet tracks ZNTL institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.