QURE Institutional Ownership & Shareholders
uniQure N.V. (QURE) is currently held by 248 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $2.96B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Avoro Capital Advisors Llc is currently the largest disclosed institutional shareholder of QURE tracked by InsiderSet, reporting ownership valued at approximately $309.88M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $154.54M, representing an estimated loss of -50.13% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 46% of the total disclosed QURE value among the investors covered in this analysis. Major shareholders include Avoro Capital Advisors Llc, Jpmorgan Chase & Co, Rtw Investments, Lp, and several other long-term asset managers with concentrated positions in uniQure N.V. (QURE).
This page ranks the largest institutional QURE shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
248
Total Reported Value
$2.96B
Largest Holder
Avoro Capital Advisors Llc
Largest Position
$309.88M
Insider Transactions (90d)
1
Latest Filing Quarter
Q2 2026
New Institutional Positions
81
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Avoro Capital Advisors Llc | 2.78% | 6,727,777 | $309,881,409 | $154,537,038 | -$155,344,371 | -50.13% | |
| Jpmorgan Chase & Co | 0.01% | 4,867,755 | $230,813,250 | $111,812,332 | -$119,000,918 | -51.56% | |
| Rtw Investments, Lp | 1.55% | 3,941,572 | $181,548,806 | $90,537,909 | -$91,010,897 | -50.13% | |
| State Street Corp | 0.00% | 2,903,825 | $133,750,180 | $66,700,860 | -$67,049,320 | -50.13% | |
| Aberdeen Group Plc | 0.18% | 2,848,117 | $131,184,269 | $65,421,247 | -$65,763,022 | -50.13% | |
| Blackrock, Inc. | 0.00% | 1,877,453 | $86,475,484 | $43,125,095 | -$43,350,389 | -50.13% | |
| Orbimed Advisors Llc | 1.58% | 1,807,486 | $83,252,805 | $41,517,953 | -$41,734,852 | -50.13% | |
| Jane Street Group, Llc | 0.05% | 1,610,483 | $74,178,847 | $36,992,795 | -$37,186,052 | -50.13% | |
| Jennison Associates Llc | 0.04% | 1,561,412 | $71,918,636 | $35,865,634 | -$36,053,002 | -50.13% | |
| Boxer Capital Management, Llc | 5.21% | 1,503,300 | $69,241,998 | $34,530,801 | -$34,711,197 | -50.13% | |
| Goldman Sachs Group Inc | 0.01% | 1,475,956 | $67,982,533 | $33,902,709 | -$34,079,824 | -50.13% | |
| Two Sigma Investments, Lp | 0.05% | 1,462,024 | $67,340,825 | $33,582,691 | -$33,758,134 | -50.13% | |
| Fmr Llc | 0.00% | 1,270,068 | $58,499,338 | $29,173,462 | -$29,325,876 | -50.13% | |
| Mak Capital One Llc | 7.95% | 1,232,051 | $56,748,269 | $28,300,211 | -$28,448,058 | -50.13% | |
| Mpm Bioimpact Llc | 3.44% | 1,225,855 | $56,462,881 | $28,157,889 | -$28,304,992 | -50.13% | |
| Morgan Stanley | 0.00% | 1,066,639 | $49,129,407 | $24,500,698 | -$24,628,709 | -50.13% | |
| Vestal Point Capital, Lp | 1.01% | 935,000 | $43,066,100 | $21,476,950 | -$21,589,150 | -50.13% | |
| Maverick Capital Ltd | 0.38% | 925,383 | $42,623,141 | $21,256,048 | -$21,367,093 | -50.13% | |
| Citadel Advisors Llc | 0.02% | 910,338 | $41,930,168 | $20,910,464 | -$21,019,704 | -50.13% | |
| Fiera Capital Corp | 0.15% | 909,141 | $41,875,034 | $20,882,969 | -$20,992,065 | -50.13% | |
| Integral Health Asset Management, Llc | 1.70% | 900,000 | $41,454,000 | $20,673,000 | -$20,781,000 | -50.13% | |
| Geode Capital Management, Llc | 0.00% | 860,631 | $39,658,136 | $19,768,694 | -$19,889,442 | -50.15% | |
| Longaeva Partners L.P. | 1.07% | 804,594 | $37,059,600 | $18,481,524 | -$18,578,076 | -50.13% | |
| Vanguard Capital Management Llc | 0.00% | 779,779 | $35,916,621 | $17,911,524 | -$18,005,097 | -50.13% | |
| Two Seas Capital Lp | 1.27% | 1,324,022 | $31,988,372 | $30,412,785 | -$1,575,587 | -4.93% | |
| Invesco Ltd. | 0.00% | 627,823 | $28,917,526 | $14,421,094 | -$14,496,432 | -50.13% | |
| First Turn Management, Llc | 3.00% | 608,925 | $28,047,086 | $13,987,007 | -$14,060,079 | -50.13% | |
| Point72 Asset Management, L.P. | 0.04% | 606,212 | $27,922,125 | $13,924,690 | -$13,997,435 | -50.13% | |
| Balyasny Asset Management L.P. | 0.05% | 586,582 | $27,017,967 | $13,473,789 | -$13,544,178 | -50.13% | |
| Kinetic Partners Management, Lp | 0.64% | 581,000 | $26,760,860 | $13,345,570 | -$13,415,290 | -50.13% | |
| Bank Of America Corp | 0.00% | 578,786 | $26,658,884 | $13,294,714 | -$13,364,170 | -50.13% | |
| 683 Capital Management, Llc | 2.44% | 575,000 | $26,484,501 | $13,207,750 | -$13,276,751 | -50.13% | |
| Gilder Gagnon Howe & Co Llc | 0.25% | 530,979 | $24,456,893 | $12,196,588 | -$12,260,305 | -50.13% | |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 1.32% | 521,677 | $24,028,443 | $11,982,921 | -$12,045,522 | -50.13% | |
| Susquehanna International Group, Llp | 0.02% | 496,897 | $22,887,076 | $11,413,724 | -$11,473,352 | -50.13% | |
| Ubs Group Ag | 0.00% | 467,571 | $21,536,321 | $10,740,106 | -$10,796,215 | -50.13% | |
| Nantahala Capital Management, Llc | 1.27% | 455,660 | $20,987,700 | $10,466,510 | -$10,521,190 | -50.13% | |
| Voss Capital, Lp | 1.04% | 450,361 | $20,743,628 | $10,344,792 | -$10,398,836 | -50.13% | |
| Rubric Capital Management Lp | 0.17% | 408,581 | $18,819,241 | $9,385,106 | -$9,434,135 | -50.13% | |
| Charles Schwab Investment Management Inc | 0.00% | 403,338 | $18,577,748 | $9,264,674 | -$9,313,074 | -50.13% | |
| Readystate Asset Management Lp | 0.75% | 400,989 | $18,469,553 | $9,210,717 | -$9,258,836 | -50.13% | |
| Vanguard Fiduciary Trust Co | 0.00% | 369,607 | $17,024,098 | $8,489,873 | -$8,534,225 | -50.13% | |
| Assenagon Asset Management S.A. | 0.02% | 693,693 | $16,759,623 | $15,934,128 | -$825,495 | -4.93% | |
| Millennium Management Llc | 0.01% | 343,126 | $15,804,384 | $7,881,604 | -$7,922,780 | -50.13% | |
| Creek Drive Management Group Llc | 9.59% | 337,000 | $15,522,220 | $7,740,890 | -$7,781,330 | -50.13% | |
| Tudor Investment Corp Et Al | 0.06% | 328,889 | $15,148,627 | $7,554,580 | -$7,594,047 | -50.13% | |
| Adar1 Capital Management, Llc | 0.70% | 324,672 | $14,954,392 | $7,457,716 | -$7,496,676 | -50.13% | |
| Marshall Wace, Llp | 0.01% | 304,702 | $14,034,574 | $6,999,005 | -$7,035,569 | -50.13% | |
| Braidwell Lp | 0.51% | 301,652 | $13,894,091 | $6,928,946 | -$6,965,145 | -50.13% | |
| Squarepoint Ops Llc | 0.03% | 280,300 | $12,910,618 | $6,438,491 | -$6,472,127 | -50.13% |
Frequently asked questions about QURE
Who are the largest institutional holders of QURE?
The largest institutional holders of QURE reported in the latest SEC Form 13F filings include Avoro Capital Advisors Llc, Jpmorgan Chase & Co, Rtw Investments, Lp, State Street Corp, and Aberdeen Group Plc. InsiderSet ranks institutional holders by their latest reported QURE position.
What is QURE institutional ownership?
This page tracks QURE positions reported by institutional investment managers through SEC Form 13F. uniQure N.V. (QURE) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own QURE?
InsiderSet currently tracks 248 institutional managers reporting QURE holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of QURE shareholders.
How much QURE stock do institutions own?
Institutional investment managers disclosed approximately $2.96B in QURE holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was QURE institutional ownership last updated?
The latest QURE institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional QURE holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its QURE position after the reporting date.
Are institutions buying or selling QURE?
Institutional buying and selling can be analyzed by comparing QURE positions across consecutive 13F reporting periods. InsiderSet's QURE Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View QURE ownership changes.
How has QURE institutional ownership changed over time?
InsiderSet tracks QURE institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.