PTGX Institutional Ownership & Shareholders
PROTAGONIST THERAPEUTICS INC (PTGX) is currently held by 347 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $8.48B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of PTGX tracked by InsiderSet, reporting ownership valued at approximately $1.26B in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $1.49B, representing an estimated gain of +18.17% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 57% of the total disclosed PTGX value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., Rtw Investments, Lp, Vanguard Portfolio Management Llc, and several other long-term asset managers with concentrated positions in PROTAGONIST THERAPEUTICS INC (PTGX).
This page ranks the largest institutional PTGX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
347
Total Reported Value
$8.48B
Largest Holder
Blackrock, Inc.
Largest Position
$1.26B
Insider Transactions (90d)
12
Latest Filing Quarter
Q2 2026
New Institutional Positions
69
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.02% | 10,307,837 | $1,263,534,678 | $1,493,090,189 | +$229,555,511 | +18.17% | |
| Rtw Investments, Lp | 5.30% | 5,061,175 | $620,398,832 | $733,111,199 | +$112,712,367 | +18.17% | |
| Vanguard Portfolio Management Llc | 0.02% | 3,629,298 | $444,879,349 | $525,703,815 | +$80,824,466 | +18.17% | |
| Wellington Management Group Llp | 0.07% | 3,416,781 | $418,829,015 | $494,920,728 | +$76,091,713 | +18.17% | |
| Ubs Group Ag | 0.07% | 3,399,221 | $416,676,511 | $492,377,162 | +$75,700,651 | +18.17% | |
| State Street Corp | 0.01% | 3,321,554 | $407,156,089 | $481,127,097 | +$73,971,008 | +18.17% | |
| Vanguard Capital Management Llc | 0.01% | 2,853,394 | $349,769,037 | $413,314,121 | +$63,545,084 | +18.17% | |
| Johnson & Johnson | 45.30% | 2,449,183 | $345,065,393 | $354,764,158 | +$9,698,765 | +2.81% | |
| Janus Henderson Group Plc | 0.15% | 2,891,527 | $304,866,424 | $418,837,686 | +$113,971,262 | +37.38% | |
| Invesco Ltd. | 0.02% | 2,340,667 | $286,918,961 | $339,045,615 | +$52,126,654 | +18.17% | |
| Price T Rowe Associates Inc | 0.03% | 2,149,662 | $263,507,000 | $311,378,541 | +$47,871,541 | +18.17% | |
| Geode Capital Management, Llc | 0.01% | 1,741,209 | $213,475,772 | $252,214,124 | +$38,738,352 | +18.15% | |
| Woodline Partners Lp | 0.54% | 1,414,173 | $173,349,326 | $204,842,959 | +$31,493,633 | +18.17% | |
| Bank Of America Corp | 0.01% | 1,324,498 | $162,356,964 | $191,853,535 | +$29,496,571 | +18.17% | |
| Jennison Associates Llc | 0.08% | 1,151,681 | $141,173,058 | $166,820,993 | +$25,647,935 | +18.17% | |
| Perceptive Advisors Llc | 1.87% | 981,879 | $120,358,728 | $142,225,173 | +$21,866,445 | +18.17% | |
| Adar1 Capital Management, Llc | 5.54% | 960,863 | $117,782,587 | $139,181,006 | +$21,398,419 | +18.17% | |
| Morgan Stanley | 0.01% | 905,992 | $111,056,578 | $131,232,941 | +$20,176,363 | +18.17% | |
| Alyeska Investment Group, L.P. | 0.28% | 889,298 | $109,010,149 | $128,814,815 | +$19,804,666 | +18.17% | |
| Hood River Capital Management Llc | 0.78% | 882,738 | $108,206,024 | $127,864,599 | +$19,658,575 | +18.17% | |
| Goldman Sachs Group Inc | 0.01% | 812,852 | $99,639,398 | $117,741,612 | +$18,102,214 | +18.17% | |
| Driehaus Capital Management Llc | 0.52% | 731,053 | $89,612,477 | $105,893,027 | +$16,280,550 | +18.17% | |
| Clearbridge Investments, Llc | 0.07% | 725,335 | $88,911,554 | $105,064,775 | +$16,153,221 | +18.17% | |
| Fmr Llc | 0.00% | 672,186 | $82,396,533 | $97,366,142 | +$14,969,609 | +18.17% | |
| Northern Trust Corp | 0.01% | 666,105 | $81,651,153 | $96,485,309 | +$14,834,156 | +18.17% | |
| American Century Companies Inc | 0.03% | 598,600 | $73,376,587 | $86,707,210 | +$13,330,623 | +18.17% | |
| Charles Schwab Investment Management Inc | 0.01% | 583,774 | $71,559,017 | $84,559,664 | +$13,000,647 | +18.17% | |
| Voya Investment Management Llc | 0.06% | 571,618 | $70,068,935 | $82,798,867 | +$12,729,932 | +18.17% | |
| Pictet Asset Management Holding Sa | 0.07% | 567,990 | $69,624,214 | $82,273,352 | +$12,649,138 | +18.17% | |
| Vanguard Fiduciary Trust Co | 0.01% | 437,747 | $53,659,027 | $63,407,653 | +$9,748,626 | +18.17% | |
| Lord, Abbett & Co. Llc | 0.14% | 398,994 | $48,909,000 | $57,794,281 | +$8,885,281 | +18.17% | |
| Principal Financial Group Inc | 0.02% | 385,262 | $47,225,415 | $55,805,201 | +$8,579,786 | +18.17% | |
| Bank Of New York Mellon Corp | 0.01% | 358,300 | $43,920,414 | $51,899,755 | +$7,979,341 | +18.17% | |
| Bnp Paribas Financial Markets | 0.02% | 301,472 | $36,954,438 | $43,668,219 | +$6,713,781 | +18.17% | |
| 683 Capital Management, Llc | 3.27% | 290,000 | $35,548,200 | $42,006,500 | +$6,458,300 | +18.17% | |
| Nuveen, Llc | 0.01% | 284,085 | $34,823,140 | $41,149,712 | +$6,326,572 | +18.17% | |
| Stephens Investment Management Group Llc | 0.37% | 281,832 | $34,546,967 | $40,823,365 | +$6,276,398 | +18.17% | |
| Bnp Paribas Asset Management Holding S.A. | 0.03% | 259,972 | $31,867,368 | $37,656,944 | +$5,789,576 | +18.17% | |
| Eagle Health Investments Lp | 5.05% | 248,322 | $30,439,311 | $35,969,442 | +$5,530,131 | +18.17% | |
| Nextbio Capital Management Lp | 12.37% | 219,333 | $26,885,839 | $31,770,385 | +$4,884,546 | +18.17% | |
| Segall Bryant & Hamill, Llc | 0.31% | 214,724 | $26,320,868 | $31,102,771 | +$4,781,903 | +18.17% | |
| Seb Asset Management Ab | 0.10% | 209,963 | $25,737,215 | $30,413,141 | +$4,675,926 | +18.17% | |
| Duquesne Family Office Llc | Stanley Druckenmiller | 0.59% | 208,900 | $25,607,000 | $30,259,165 | +$4,652,165 | +18.17% |
| Public Sector Pension Investment Board | 0.07% | 207,688 | $25,458,395 | $30,083,607 | +$4,625,212 | +18.17% | |
| Citigroup Inc | 0.01% | 198,668 | $24,352,723 | $28,777,060 | +$4,424,337 | +18.17% | |
| Jpmorgan Chase & Co | 0.00% | 183,098 | $22,569,540 | $26,521,745 | +$3,952,205 | +17.51% | |
| Dimensional Fund Advisors Lp | 0.00% | 178,152 | $21,836,172 | $25,805,317 | +$3,969,145 | +18.18% | |
| Affinity Asset Advisors, Llc | 1.03% | 172,125 | $21,099,083 | $24,932,306 | +$3,833,223 | +18.17% | |
| Fisher Asset Management, Llc | 0.01% | 170,524 | $20,902,831 | $24,700,401 | +$3,797,570 | +18.17% | |
| Boxer Capital Management, Llc | 1.57% | 170,000 | $20,838,600 | $24,624,500 | +$3,785,900 | +18.17% |
Frequently asked questions about PTGX
Who are the largest institutional holders of PTGX?
The largest institutional holders of PTGX reported in the latest SEC Form 13F filings include Blackrock, Inc., Rtw Investments, Lp, Vanguard Portfolio Management Llc, Wellington Management Group Llp, and Ubs Group Ag. InsiderSet ranks institutional holders by their latest reported PTGX position.
What is PTGX institutional ownership?
This page tracks PTGX positions reported by institutional investment managers through SEC Form 13F. PROTAGONIST THERAPEUTICS INC (PTGX) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own PTGX?
InsiderSet currently tracks 347 institutional managers reporting PTGX holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of PTGX shareholders.
How much PTGX stock do institutions own?
Institutional investment managers disclosed approximately $8.48B in PTGX holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was PTGX institutional ownership last updated?
The latest PTGX institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional PTGX holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its PTGX position after the reporting date.
Are institutions buying or selling PTGX?
Institutional buying and selling can be analyzed by comparing PTGX positions across consecutive 13F reporting periods. InsiderSet's PTGX Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View PTGX ownership changes.
How has PTGX institutional ownership changed over time?
InsiderSet tracks PTGX institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.