PROTAGONIST THERAPEUTICS INC (PTGX) Institutional Ownership Changes & 13F Activity

PROTAGONIST THERAPEUTICS INC (PTGX). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Farallon Capital Management Llc, Invesco Ltd., Price T Rowe Associates Inc, Alyeska Investment Group, L.P., and Perceptive Advisors Llc.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Envestnet Asset Management IncBuy+2,817+17.3%19,134$2.35MQ2 2026Sep 23, 2026
State Street CorpBuy+204,805+6.6%3,321,554$407.16MQ2 2026Sep 22, 2026
Manufacturers Life Insurance Company, TheSell-19,263-15.1%108,555$13.31MQ2 2026Sep 09, 2026
California State Teachers Retirement SystemBuy+284+0.5%58,961$7.23MQ2 2026Aug 24, 2026
Fulcrum Asset Management LlpBuy+46—46$5.59KQ2 2026Aug 18, 2026
Seven Fleet Capital Management LpBuy+41,400+1035.0%45,400$5.57MQ2 2026Aug 17, 2026
Empowered Funds, LlcSell-57-2.5%2,264$277.52KQ2 2026Aug 17, 2026
Farallon Capital Management LlcBuy+6,348,906—6,348,906$778.25MQ2 2026Aug 14, 2026
Invesco Ltd.Buy+2,340,667—2,340,667$286.92MQ2 2026Aug 14, 2026
Price T Rowe Associates IncBuy+484,165+29.1%2,149,662$263.51MQ2 2026Aug 14, 2026
Alyeska Investment Group, L.P.Buy+296,101+49.9%889,298$109.01MQ2 2026Aug 14, 2026
Perceptive Advisors LlcSell-249,000-20.2%981,879$120.36MQ2 2026Aug 14, 2026
Lord, Abbett & Co. LlcBuy+235,535+144.1%398,994$48.91MQ2 2026Aug 14, 2026
Holocene Advisors, LpSell-201,421-96.0%8,495$1.04MQ2 2026Aug 14, 2026
Wellington Management Group LlpSell-182,863-5.1%3,416,781$418.83MQ2 2026Aug 14, 2026
Ameriprise Financial IncBuy+143,810—143,810$17.63MQ2 2026Aug 14, 2026
Nomura Asset Management International Inc.Buy+141,081—141,081$17.29MQ2 2026Aug 14, 2026
Susquehanna International Group, LlpSell-110,514-65.9%57,062$6.99MQ2 2026Aug 14, 2026
Catalio Capital Management, LpBuy+106,799—106,799$13.09MQ2 2026Aug 14, 2026
Balyasny Asset Management L.P.Sell-97,701-96.4%3,598$441.04KQ2 2026Aug 14, 2026
683 Capital Management, LlcSell-65,000-18.3%290,000$35.55MQ2 2026Aug 14, 2026
Eversept Partners, LpBuy+58,504—58,504$7.17MQ2 2026Aug 14, 2026
Stempoint Capital LpSell-56,274-77.5%16,303$2.00MQ2 2026Aug 14, 2026
Hood River Capital Management LlcBuy+53,453+6.4%882,738$108.21MQ2 2026Aug 14, 2026
Castleark Management LlcBuy+50,570—50,570$6.20MQ2 2026Aug 14, 2026
Duquesne Family Office LlcBuy+49,200+30.8%208,900$25.61MQ2 2026Aug 14, 2026
Caption Management, LlcBuy+45,000—45,000$5.52MQ2 2026Aug 14, 2026
Wells Fargo & Company/MnBuy+41,872+139.2%71,944$8.82MQ2 2026Aug 14, 2026
Bellevue Group AgBuy+41,235+285.4%55,682$6.83MQ2 2026Aug 14, 2026
Goldman Sachs Group IncBuy+33,907+4.4%812,852$99.64MQ2 2026Aug 14, 2026
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Frequently asked questions about PTGX activity

  • Which institutional owners are buying PTGX?

    Institutional owners buying PTGX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in PTGX activity?

    "Buy" means an investor increased their reported position in PTGX compared to the prior reporting period. This reflects growing exposure to PROTAGONIST THERAPEUTICS INC (PTGX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in PTGX increasing?

    Institutional interest in PTGX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.