ORKA Institutional Ownership & Shareholders
ORUKA THERAPEUTICS INC (ORKA) is currently held by 252 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $6.72B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Fmr Llc is currently the largest disclosed institutional shareholder of ORKA tracked by InsiderSet, reporting ownership valued at approximately $862.02M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $877.41M, representing an estimated gain of +1.79% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 53% of the total disclosed ORKA value among the investors covered in this analysis. Major shareholders include Fmr Llc, Blackrock, Inc., Venrock Adviser, Llc, and several other long-term asset managers with concentrated positions in ORUKA THERAPEUTICS INC (ORKA).
This page ranks the largest institutional ORKA shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
252
Total Reported Value
$6.72B
Largest Holder
Fmr Llc
Largest Position
$862.02M
Insider Transactions (90d)
28
Latest Filing Quarter
Q2 2026
New Institutional Positions
115
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.04% | 9,057,645 | $862,016,075 | $877,414,071 | +$15,397,996 | +1.79% | |
| Blackrock, Inc. | 0.01% | 4,990,181 | $474,915,526 | $483,398,833 | +$8,483,307 | +1.79% | |
| Venrock Adviser, Llc | 11.97% | 4,148,428 | $394,805,893 | $401,858,220 | +$7,052,327 | +1.79% | |
| Fairmount Funds Management Llc | 23.31% | 3,705,262 | $352,629,785 | $358,928,730 | +$6,298,945 | +1.79% | |
| Capital World Investors | 0.04% | 3,401,639 | $323,733,984 | $329,516,770 | +$5,782,786 | +1.79% | |
| Rtw Investments, Lp | 2.55% | 3,139,030 | $298,741,485 | $304,077,836 | +$5,336,351 | +1.79% | |
| State Street Corp | 0.01% | 2,673,090 | $254,384,117 | $258,942,228 | +$4,558,111 | +1.79% | |
| Vanguard Capital Management Llc | 0.00% | 2,360,971 | $224,693,610 | $228,707,261 | +$4,013,651 | +1.79% | |
| Paradigm Biocapital Advisors Lp | 3.82% | 2,144,526 | $204,094,539 | $207,740,234 | +$3,645,695 | +1.79% | |
| Deep Track Capital, Lp | 2.70% | 1,926,000 | $183,297,420 | $186,571,620 | +$3,274,200 | +1.79% | |
| Bellevue Group Ag | 3.32% | 1,657,190 | $157,714,772 | $160,531,995 | +$2,817,223 | +1.79% | |
| Remedium Capital Partners, Llc | 32.99% | 1,565,661 | $149,003,957 | $151,665,581 | +$2,661,624 | +1.79% | |
| Ra Capital Management, L.P. | 1.29% | 1,554,597 | $147,950,996 | $150,593,811 | +$2,642,815 | +1.79% | |
| Viking Global Investors | Ole Andreas Halvorsen | 0.41% | 1,503,478 | $143,086,001 | $145,641,914 | +$2,555,913 | +1.79% |
| Geode Capital Management, Llc | 0.01% | 1,429,954 | $136,113,846 | $138,519,644 | +$2,405,798 | +1.77% | |
| Perceptive Advisors Llc | 1.99% | 1,345,063 | $128,009,646 | $130,296,253 | +$2,286,607 | +1.79% | |
| Polar Capital Holdings Plc | 0.33% | 1,228,609 | $116,926,719 | $119,015,354 | +$2,088,635 | +1.79% | |
| Citadel Advisors Llc | 0.06% | 1,119,011 | $106,496,277 | $108,398,596 | +$1,902,319 | +1.79% | |
| T. Rowe Price Investment Management, Inc. | 0.07% | 1,103,743 | $105,044,000 | $106,919,584 | +$1,875,584 | +1.79% | |
| Bnp Paribas Financial Markets | 0.05% | 1,079,015 | $102,689,858 | $104,524,183 | +$1,834,325 | +1.79% | |
| Price T Rowe Associates Inc | 0.01% | 838,603 | $79,811,000 | $81,235,473 | +$1,424,473 | +1.78% | |
| Avidity Partners Management Lp | 11.59% | 760,424 | $72,369,552 | $73,662,273 | +$1,292,721 | +1.79% | |
| Summit Partners Public Asset Management, Llc | 1.63% | 658,301 | $62,650,506 | $63,769,618 | +$1,119,112 | +1.79% | |
| Aberdeen Group Plc | 0.09% | 646,943 | $61,569,565 | $62,669,368 | +$1,099,803 | +1.79% | |
| Ubs Group Ag | 0.01% | 639,363 | $60,848,177 | $61,935,094 | +$1,086,917 | +1.79% | |
| Jpmorgan Chase & Co | 0.00% | 655,027 | $60,736,334 | $63,452,465 | +$2,716,131 | +4.47% | |
| Westfield Capital Management Co Lp | 0.20% | 631,433 | $60,093,479 | $61,166,915 | +$1,073,436 | +1.79% | |
| Pictet Asset Management Holding Sa | 0.06% | 619,076 | $58,914,871 | $59,969,892 | +$1,055,021 | +1.79% | |
| Affinity Asset Advisors, Llc | 2.75% | 590,000 | $56,150,300 | $57,153,300 | +$1,003,000 | +1.79% | |
| Vanguard Portfolio Management Llc | 0.00% | 582,409 | $55,427,865 | $56,417,960 | +$990,095 | +1.79% | |
| Cormorant Asset Management, Lp | 2.60% | 533,340 | $50,757,968 | $51,664,646 | +$906,678 | +1.79% | |
| Charles Schwab Investment Management Inc | 0.01% | 433,405 | $41,247,154 | $41,983,942 | +$736,788 | +1.79% | |
| Northern Trust Corp | 0.00% | 428,891 | $40,817,558 | $41,546,671 | +$729,113 | +1.79% | |
| Voya Investment Management Llc | 0.03% | 401,149 | $38,177,350 | $38,859,304 | +$681,954 | +1.79% | |
| Lord, Abbett & Co. Llc | 0.11% | 390,064 | $37,122,000 | $37,785,500 | +$663,500 | +1.79% | |
| Vanguard Fiduciary Trust Co | 0.01% | 365,630 | $34,797,007 | $35,418,578 | +$621,571 | +1.79% | |
| Massachusetts Financial Services Co | 0.01% | 364,102 | $34,651,587 | $35,270,561 | +$618,974 | +1.79% | |
| Synergy Asset Management, Llc | 3.20% | 356,301 | $33,909,166 | $34,514,878 | +$605,712 | +1.79% | |
| Adage Capital Partners Gp, L.L.C. | 0.05% | 355,003 | $33,785,636 | $34,389,141 | +$603,505 | +1.79% | |
| Bank Of America Corp | 0.00% | 352,824 | $33,578,260 | $34,178,061 | +$599,801 | +1.79% | |
| Silverarc Capital Management, Llc | 3.74% | 352,802 | $33,576,166 | $34,175,930 | +$599,764 | +1.79% | |
| Candriam S.C.A. | 0.15% | 352,716 | $33,535,685 | $34,167,599 | +$631,914 | +1.88% | |
| Holocene Advisors, Lp | 0.07% | 305,951 | $29,117,357 | $29,637,473 | +$520,116 | +1.79% | |
| Jennison Associates Llc | 0.02% | 299,257 | $28,480,289 | $28,989,026 | +$508,737 | +1.79% | |
| Woodline Partners Lp | 0.08% | 285,247 | $27,146,957 | $27,631,877 | +$484,920 | +1.79% | |
| Braidwell Lp | 0.98% | 278,164 | $26,472,868 | $26,945,747 | +$472,879 | +1.79% | |
| Siren, L.L.C. | 0.48% | 250,000 | $23,792,500 | $24,217,500 | +$425,000 | +1.79% | |
| Nuveen, Llc | 0.01% | 249,267 | $23,722,741 | $24,146,494 | +$423,753 | +1.79% | |
| Eventide Asset Management, Llc | 0.31% | 240,000 | $22,840,800 | $23,248,800 | +$408,000 | +1.79% | |
| Nomura Asset Management International Inc. | 0.03% | 219,039 | $20,846,000 | $21,218,308 | +$372,308 | +1.79% |
Frequently asked questions about ORKA
Who are the largest institutional holders of ORKA?
The largest institutional holders of ORKA reported in the latest SEC Form 13F filings include Fmr Llc, Blackrock, Inc., Venrock Adviser, Llc, Fairmount Funds Management Llc, and Capital World Investors. InsiderSet ranks institutional holders by their latest reported ORKA position.
What is ORKA institutional ownership?
This page tracks ORKA positions reported by institutional investment managers through SEC Form 13F. ORUKA THERAPEUTICS INC (ORKA) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own ORKA?
InsiderSet currently tracks 252 institutional managers reporting ORKA holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of ORKA shareholders.
How much ORKA stock do institutions own?
Institutional investment managers disclosed approximately $6.72B in ORKA holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was ORKA institutional ownership last updated?
The latest ORKA institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional ORKA holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its ORKA position after the reporting date.
Are institutions buying or selling ORKA?
Institutional buying and selling can be analyzed by comparing ORKA positions across consecutive 13F reporting periods. InsiderSet's ORKA Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View ORKA ownership changes.
How has ORKA institutional ownership changed over time?
InsiderSet tracks ORKA institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.