ORUKA THERAPEUTICS INC (ORKA) Institutional Shareholders
ORUKA THERAPEUTICS INC (ORKA) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $6.75B in ORKA holdings during the latest filing period.
Fmr Llc is currently the largest disclosed institutional shareholder of ORKA tracked by InsiderSet, reporting ownership valued at approximately $862.02M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $860.11M, representing an estimated loss of -0.22% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 53% of the total disclosed ORKA value among the investors covered in this analysis. Major shareholders include Fmr Llc, Blackrock, Inc., Venrock Adviser, Llc, and several other long-term asset managers with concentrated positions in ORUKA THERAPEUTICS INC (ORKA).
This page ranks the largest institutional ORKA shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
246
Total Reported Value
$6.75B
Largest Holder
Fmr Llc
Largest Position
$862.02M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
128
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.04% | 9,057,645 | $862,016,075 | $860,113,969 | -$1,902,106 | -0.22% | |
| Blackrock, Inc. | 0.01% | 4,990,181 | $474,915,526 | $473,867,588 | -$1,047,938 | -0.22% | |
| Venrock Adviser, Llc | 11.97% | 4,148,428 | $394,805,893 | $393,934,723 | -$871,170 | -0.22% | |
| Fairmount Funds Management Llc | 23.31% | 3,705,262 | $352,629,785 | $351,851,680 | -$778,105 | -0.22% | |
| Capital World Investors | 0.04% | 3,401,639 | $323,733,984 | $323,019,639 | -$714,345 | -0.22% | |
| Rtw Investments, Lp | 2.55% | 3,139,030 | $298,741,485 | $298,082,289 | -$659,196 | -0.22% | |
| State Street Corp | 0.01% | 2,673,090 | $254,384,117 | $253,836,626 | -$547,491 | -0.22% | |
| Vanguard Capital Management Llc | 0.00% | 2,360,971 | $224,693,610 | $224,197,806 | -$495,804 | -0.22% | |
| Paradigm Biocapital Advisors Lp | 3.82% | 2,144,526 | $204,094,539 | $203,644,189 | -$450,350 | -0.22% | |
| Deep Track Capital, Lp | 2.70% | 1,926,000 | $183,297,420 | $182,892,960 | -$404,460 | -0.22% | |
| Bellevue Group Ag | 3.32% | 1,657,190 | $157,714,772 | $157,366,762 | -$348,010 | -0.22% | |
| Remedium Capital Partners, Llc | 32.99% | 1,565,661 | $149,003,957 | $148,675,169 | -$328,788 | -0.22% | |
| Ra Capital Management, L.P. | 1.29% | 1,554,597 | $147,950,996 | $147,624,531 | -$326,465 | -0.22% | |
| Viking Global Investors | Ole Andreas Halvorsen | 0.41% | 1,503,478 | $143,086,001 | $142,770,271 | -$315,730 | -0.22% |
| Geode Capital Management, Llc | 0.01% | 1,429,954 | $136,113,846 | $135,788,432 | -$325,414 | -0.24% | |
| Perceptive Advisors Llc | 1.99% | 1,345,063 | $128,009,646 | $127,727,182 | -$282,464 | -0.22% | |
| Polar Capital Holdings Plc | 0.33% | 1,228,609 | $116,926,719 | $116,668,711 | -$258,008 | -0.22% | |
| Citadel Advisors Llc | 0.06% | 1,119,011 | $106,496,277 | $106,261,285 | -$234,992 | -0.22% | |
| T. Rowe Price Investment Management, Inc. | 0.07% | 1,103,743 | $105,044,000 | $104,811,435 | -$232,565 | -0.22% | |
| Bnp Paribas Financial Markets | 0.05% | 1,079,015 | $102,689,858 | $102,463,264 | -$226,594 | -0.22% | |
| Price T Rowe Associates Inc | 0.01% | 838,603 | $79,811,000 | $79,633,741 | -$177,259 | -0.22% | |
| Avidity Partners Management Lp | 11.59% | 760,424 | $72,369,552 | $72,209,863 | -$159,689 | -0.22% | |
| Summit Partners Public Asset Management, Llc | 1.63% | 658,301 | $62,650,506 | $62,512,263 | -$138,243 | -0.22% | |
| Aberdeen Group Plc | 0.09% | 646,943 | $61,569,565 | $61,433,707 | -$135,858 | -0.22% | |
| Ubs Group Ag | 0.01% | 639,363 | $60,848,177 | $60,713,910 | -$134,267 | -0.22% | |
| Jpmorgan Chase & Co | 0.00% | 655,027 | $60,736,334 | $62,201,364 | +$1,465,030 | +2.41% | |
| Westfield Capital Management Co Lp | 0.20% | 631,433 | $60,093,479 | $59,960,878 | -$132,601 | -0.22% | |
| Pictet Asset Management Holding Sa | 0.06% | 619,076 | $58,914,871 | $58,787,457 | -$127,414 | -0.22% | |
| Affinity Asset Advisors, Llc | 2.75% | 590,000 | $56,150,300 | $56,026,400 | -$123,900 | -0.22% | |
| Vanguard Portfolio Management Llc | 0.00% | 582,409 | $55,427,865 | $55,305,559 | -$122,306 | -0.22% | |
| Cormorant Asset Management, Lp | 2.60% | 533,340 | $50,757,968 | $50,645,966 | -$112,002 | -0.22% | |
| Charles Schwab Investment Management Inc | 0.01% | 433,405 | $41,247,154 | $41,156,139 | -$91,015 | -0.22% | |
| Northern Trust Corp | 0.00% | 428,891 | $40,817,558 | $40,727,489 | -$90,069 | -0.22% | |
| Voya Investment Management Llc | 0.03% | 401,149 | $38,177,350 | $38,093,109 | -$84,241 | -0.22% | |
| Lord, Abbett & Co. Llc | 0.11% | 390,064 | $37,122,000 | $37,040,477 | -$81,523 | -0.22% | |
| Vanguard Fiduciary Trust Co | 0.01% | 365,630 | $34,797,007 | $34,720,225 | -$76,782 | -0.22% | |
| Massachusetts Financial Services Co | 0.01% | 364,102 | $34,651,587 | $34,575,126 | -$76,461 | -0.22% | |
| Synergy Asset Management, Llc | 3.20% | 356,301 | $33,909,166 | $33,834,343 | -$74,823 | -0.22% | |
| Adage Capital Partners Gp, L.L.C. | 0.05% | 355,003 | $33,785,636 | $33,711,085 | -$74,551 | -0.22% | |
| Bank Of America Corp | 0.00% | 352,824 | $33,578,260 | $33,504,167 | -$74,093 | -0.22% | |
| Silverarc Capital Management, Llc | 3.74% | 352,802 | $33,576,166 | $33,502,078 | -$74,088 | -0.22% | |
| Candriam S.C.A. | 0.15% | 352,716 | $33,535,685 | $33,493,911 | -$41,774 | -0.12% | |
| Holocene Advisors, Lp | 0.07% | 305,951 | $29,117,357 | $29,053,107 | -$64,250 | -0.22% | |
| Jennison Associates Llc | 0.02% | 299,257 | $28,480,289 | $28,417,445 | -$62,844 | -0.22% | |
| Woodline Partners Lp | 0.08% | 285,247 | $27,146,957 | $27,087,055 | -$59,902 | -0.22% | |
| Braidwell Lp | 0.98% | 278,164 | $26,472,868 | $26,414,453 | -$58,415 | -0.22% | |
| Siren, L.L.C. | 0.48% | 250,000 | $23,792,500 | $23,740,000 | -$52,500 | -0.22% | |
| Nuveen, Llc | 0.01% | 249,267 | $23,722,741 | $23,670,394 | -$52,347 | -0.22% | |
| Eventide Asset Management, Llc | 0.31% | 240,000 | $22,840,800 | $22,790,400 | -$50,400 | -0.22% | |
| Blackstone Inc. | 0.07% | 237,108 | $22,565,568 | $22,515,776 | -$49,792 | -0.22% |
Frequently asked questions about ORKA
Who owns the most ORKA stock?
The largest holders of ORKA are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ORUKA THERAPEUTICS INC (ORKA).
Is ORKA widely held by superinvestors?
Many widely followed stocks like ORKA appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ORKA is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.