APOGEE THERAPEUTICS INC (APGE) Top Institutional Shareholders
APOGEE THERAPEUTICS INC (APGE) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $5.58B in APGE holdings during the latest filing period.
Fmr Llc is currently the largest disclosed institutional shareholder of APGE tracked by InsiderSet, reporting ownership valued at approximately $779.61M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $819.06M, representing an estimated gain of +5.06% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 60% of the total disclosed APGE value among the investors covered in this analysis. Major shareholders include Fmr Llc, Venrock Adviser, Llc, Wellington Management Group Llp, and several other long-term asset managers with concentrated positions in APOGEE THERAPEUTICS INC (APGE).
This page ranks the largest institutional APGE shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
220
Total Reported Value
$5.58B
Largest Holder
Fmr Llc
Largest Position
$779.61M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
144
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.04% | 9,262,291 | $779,606,994 | $819,064,393 | +$39,457,399 | +5.06% | |
| Venrock Adviser, Llc | 26.68% | 8,493,321 | $714,882,829 | $751,064,376 | +$36,181,547 | +5.06% | |
| Wellington Management Group Llp | 0.07% | 4,375,703 | $368,302,921 | $386,943,416 | +$18,640,495 | +5.06% | |
| Blackrock, Inc. | 0.01% | 4,085,651 | $343,889,202 | $361,294,118 | +$17,404,916 | +5.06% | |
| Rtw Investments, Lp | 2.33% | 2,782,097 | $234,169,104 | $246,020,838 | +$11,851,734 | +5.06% | |
| Vanguard Capital Management Llc | 0.01% | 2,502,095 | $210,601,336 | $221,260,261 | +$10,658,925 | +5.06% | |
| Janus Henderson Group Plc | 0.10% | 2,360,596 | $198,808,884 | $208,747,504 | +$9,938,620 | +5.00% | |
| State Street Corp | 0.01% | 2,162,964 | $182,056,680 | $191,270,907 | +$9,214,227 | +5.06% | |
| Driehaus Capital Management Llc | 1.19% | 1,920,800 | $161,673,736 | $169,856,344 | +$8,182,608 | +5.06% | |
| Perceptive Advisors Llc | 2.56% | 1,540,384 | $129,654,121 | $136,216,157 | +$6,562,036 | +5.06% | |
| Paradigm Biocapital Advisors Lp | 2.32% | 1,348,243 | $113,481,613 | $119,225,128 | +$5,743,515 | +5.06% | |
| Affinity Asset Advisors, Llc | 6.34% | 1,284,926 | $108,152,221 | $113,626,006 | +$5,473,785 | +5.06% | |
| Geode Capital Management, Llc | 0.01% | 1,217,289 | $102,483,956 | $107,644,866 | +$5,160,910 | +5.04% | |
| Ubs Group Ag | 0.02% | 1,144,328 | $96,318,088 | $101,192,925 | +$4,874,837 | +5.06% | |
| Vestal Point Capital, Lp | 2.59% | 1,100,000 | $92,587,000 | $97,273,000 | +$4,686,000 | +5.06% | |
| Frontier Capital Management Co Llc | 0.92% | 1,064,483 | $89,597,516 | $94,132,232 | +$4,534,716 | +5.06% | |
| Bank Of America Corp | 0.01% | 900,871 | $75,826,311 | $79,664,023 | +$3,837,712 | +5.06% | |
| Alliancebernstein L.P. | 0.02% | 990,297 | $74,747,618 | $87,571,964 | +$12,824,346 | +17.16% | |
| Mercer Global Advisors Inc | 0.10% | 831,428 | $69,981,295 | $73,523,178 | +$3,541,883 | +5.06% | |
| Goldman Sachs Group Inc | 0.01% | 652,590 | $54,928,500 | $57,708,534 | +$2,780,034 | +5.06% | |
| Citadel Advisors Llc | 0.04% | 598,902 | $50,409,581 | $52,960,904 | +$2,551,323 | +5.06% | |
| Morgan Stanley | 0.00% | 595,032 | $50,083,937 | $52,618,680 | +$2,534,743 | +5.06% | |
| Jennison Associates Llc | 0.03% | 585,016 | $49,240,797 | $51,732,965 | +$2,492,168 | +5.06% | |
| Remedium Capital Partners, Llc | 15.36% | 583,591 | $49,120,854 | $51,606,952 | +$2,486,098 | +5.06% | |
| First Light Asset Management, Llc | 4.35% | 576,684 | $48,539,492 | $50,996,166 | +$2,456,674 | +5.06% | |
| Eventide Asset Management, Llc | 0.78% | 557,423 | $46,918,294 | $49,292,916 | +$2,374,622 | +5.06% | |
| Polar Capital Holdings Plc | 0.20% | 539,177 | $45,382,528 | $47,679,422 | +$2,296,894 | +5.06% | |
| First Turn Management, Llc | 4.83% | 513,770 | $43,244,021 | $45,432,681 | +$2,188,660 | +5.06% | |
| Braidwell Lp | 1.34% | 478,667 | $40,289,401 | $42,328,523 | +$2,039,122 | +5.06% | |
| Novo Holdings A/S | 3.07% | 450,000 | $37,876,500 | $39,793,500 | +$1,917,000 | +5.06% | |
| Federated Hermes, Inc. | 0.06% | 442,738 | $37,265,257 | $39,151,321 | +$1,886,064 | +5.06% | |
| Balyasny Asset Management L.P. | 0.07% | 438,654 | $36,921,507 | $38,790,173 | +$1,868,666 | +5.06% | |
| Charles Schwab Investment Management Inc | 0.01% | 420,684 | $35,408,972 | $37,201,086 | +$1,792,114 | +5.06% | |
| Franklin Resources Inc | 0.01% | 405,538 | $34,134,157 | $35,861,725 | +$1,727,568 | +5.06% | |
| Vanguard Portfolio Management Llc | 0.00% | 396,330 | $33,359,096 | $35,047,462 | +$1,688,366 | +5.06% | |
| Northern Trust Corp | 0.00% | 390,879 | $32,900,285 | $34,565,430 | +$1,665,145 | +5.06% | |
| Opaleye Management Inc. | 4.32% | 390,000 | $32,826,300 | $34,487,700 | +$1,661,400 | +5.06% | |
| Great Point Partners Llc | 7.71% | 374,000 | $31,479,580 | $33,072,820 | +$1,593,240 | +5.06% | |
| Vanguard Fiduciary Trust Co | 0.01% | 368,961 | $31,055,447 | $32,627,221 | +$1,571,774 | +5.06% | |
| Loomis Sayles & Co L P | 0.04% | 362,781 | $30,535,277 | $32,080,724 | +$1,545,447 | +5.06% | |
| Capital World Investors | 0.00% | 348,674 | $29,347,891 | $30,833,242 | +$1,485,351 | +5.06% | |
| Fairmount Funds Management Llc | 1.82% | 298,647 | $25,137,118 | $26,409,354 | +$1,272,236 | +5.06% | |
| Deep Track Capital, Lp | 0.49% | 285,000 | $23,988,450 | $25,202,550 | +$1,214,100 | +5.06% | |
| Two Sigma Investments, Lp | 0.02% | 281,386 | $23,684,260 | $24,882,964 | +$1,198,704 | +5.06% | |
| Woodline Partners Lp | 0.08% | 261,120 | $21,978,470 | $23,090,842 | +$1,112,372 | +5.06% | |
| Pictet Asset Management Holding Sa | 0.02% | 261,050 | $21,972,579 | $23,084,652 | +$1,112,073 | +5.06% | |
| Adage Capital Partners Gp, L.L.C. | 0.03% | 250,000 | $21,042,500 | $22,107,500 | +$1,065,000 | +5.06% | |
| Candriam S.C.A. | 0.10% | 223,541 | $18,815,446 | $19,767,731 | +$952,285 | +5.06% | |
| Bnp Paribas Financial Markets | 0.01% | 220,099 | $18,525,733 | $19,463,355 | +$937,622 | +5.06% | |
| Td Asset Management Inc | 0.01% | 184,792 | $15,553,943 | $16,341,157 | +$787,214 | +5.06% |
Frequently asked questions about APGE
Who owns the most APGE stock?
The largest holders of APGE are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for APOGEE THERAPEUTICS INC (APGE).
Is APGE widely held by superinvestors?
Many widely followed stocks like APGE appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly APGE is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.