TANGO THERAPEUTICS INC (TNGX) Institutional Shareholders
TANGO THERAPEUTICS INC (TNGX) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $3.74B in TNGX holdings during the latest filing period.
Rtw Investments, Lp is currently the largest disclosed institutional shareholder of TNGX tracked by InsiderSet, reporting ownership valued at approximately $278.25M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $343.82M, representing an estimated gain of +23.57% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 54% of the total disclosed TNGX value among the investors covered in this analysis. Major shareholders include Rtw Investments, Lp, Adage Capital Partners Gp, L.L.C., Boxer Capital Management, Llc, and several other long-term asset managers with concentrated positions in TANGO THERAPEUTICS INC (TNGX).
This page ranks the largest institutional TNGX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
194
Total Reported Value
$3.74B
Largest Holder
Rtw Investments, Lp
Largest Position
$278.25M
Insider Transactions (90d)
11
Latest Filing Quarter
Q2 2026
New Institutional Positions
163
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Rtw Investments, Lp | 2.77% | 13,300,620 | $278,248,970 | $343,821,027 | +$65,572,057 | +23.57% | |
| Adage Capital Partners Gp, L.L.C. | 0.41% | 12,809,485 | $267,974,426 | $331,125,187 | +$63,150,761 | +23.57% | |
| Boxer Capital Management, Llc | 29.87% | 10,876,219 | $227,530,501 | $281,150,261 | +$53,619,760 | +23.57% | |
| Tcg Crossover Management, Llc | 6.30% | 10,531,071 | $220,310,005 | $272,228,185 | +$51,918,180 | +23.57% | |
| Fmr Llc | 0.01% | 9,905,919 | $207,231,826 | $256,068,006 | +$48,836,180 | +23.57% | |
| Farallon Capital Management Llc | 1.24% | 9,097,411 | $190,317,838 | $235,168,074 | +$44,850,236 | +23.57% | |
| Blackrock, Inc. | 0.00% | 8,748,045 | $183,009,100 | $226,136,963 | +$43,127,863 | +23.57% | |
| Woodline Partners Lp | 0.63% | 8,000,013 | $167,360,272 | $206,800,336 | +$39,440,064 | +23.57% | |
| Nextech Invest, Ltd. | 10.70% | 7,266,081 | $152,006,415 | $187,828,194 | +$35,821,779 | +23.57% | |
| Trv Gp Iv, Llc | 49.96% | 6,374,574 | $133,356,088 | $164,782,738 | +$31,426,650 | +23.57% | |
| Siren, L.L.C. | 3.28% | 5,657,105 | $118,346,637 | $146,236,164 | +$27,889,527 | +23.57% | |
| Vanguard Capital Management Llc | 0.00% | 5,161,431 | $107,977,137 | $133,422,991 | +$25,445,854 | +23.57% | |
| Goldman Sachs Group Inc | 0.01% | 5,076,392 | $106,198,121 | $131,224,733 | +$25,026,612 | +23.57% | |
| State Street Corp | 0.00% | 4,651,894 | $97,317,622 | $120,251,460 | +$22,933,838 | +23.57% | |
| Deerfield Management Company, L.P. | 1.02% | 4,146,813 | $86,751,328 | $107,195,116 | +$20,443,788 | +23.57% | |
| Paradigm Biocapital Advisors Lp | 1.71% | 4,009,679 | $83,882,485 | $103,650,202 | +$19,767,717 | +23.57% | |
| Holocene Advisors, Lp | 0.20% | 3,932,603 | $82,270,055 | $101,657,788 | +$19,387,733 | +23.57% | |
| Balyasny Asset Management L.P. | 0.16% | 3,826,659 | $80,053,706 | $98,919,135 | +$18,865,429 | +23.57% | |
| Logos Global Management Lp | 3.23% | 3,000,000 | $62,760,000 | $77,550,000 | +$14,790,000 | +23.57% | |
| Deep Track Capital, Lp | 1.19% | 2,750,000 | $57,530,000 | $71,087,500 | +$13,557,500 | +23.57% | |
| Geode Capital Management, Llc | 0.00% | 2,675,777 | $55,990,239 | $69,168,835 | +$13,178,596 | +23.54% | |
| Caligan Partners Lp | 3.56% | 2,408,798 | $50,392,054 | $62,267,428 | +$11,875,374 | +23.57% | |
| Bellevue Group Ag | 1.19% | 2,400,000 | $50,208,000 | $62,040,000 | +$11,832,000 | +23.57% | |
| Janus Henderson Group Plc | 0.02% | 2,394,972 | $50,066,890 | $61,910,026 | +$11,843,136 | +23.65% | |
| Vivo Capital, Llc | 3.76% | 2,154,780 | $45,077,998 | $55,701,063 | +$10,623,065 | +23.57% | |
| Morgan Stanley | 0.00% | 1,477,488 | $30,909,048 | $38,193,065 | +$7,284,017 | +23.57% | |
| Cormorant Asset Management, Lp | 1.50% | 1,425,000 | $29,811,000 | $36,836,250 | +$7,025,250 | +23.57% | |
| Franklin Resources Inc | 0.01% | 1,296,283 | $27,118,241 | $33,508,916 | +$6,390,675 | +23.57% | |
| Candriam S.C.A. | 0.14% | 1,269,246 | $26,552,626 | $32,810,009 | +$6,257,383 | +23.57% | |
| Nantahala Capital Management, Llc | 1.63% | 1,250,452 | $26,159,456 | $32,324,184 | +$6,164,728 | +23.57% | |
| Vanguard Portfolio Management Llc | 0.00% | 901,466 | $18,858,669 | $23,302,896 | +$4,444,227 | +23.57% | |
| Northern Trust Corp | 0.00% | 862,940 | $18,052,704 | $22,306,999 | +$4,254,295 | +23.57% | |
| Charles Schwab Investment Management Inc | 0.00% | 838,675 | $17,545,081 | $21,679,749 | +$4,134,668 | +23.57% | |
| Perceptive Advisors Llc | 0.33% | 808,153 | $16,906,561 | $20,890,755 | +$3,984,194 | +23.57% | |
| Arrowmark Colorado Holdings Llc | 0.39% | 708,385 | $14,819,414 | $18,311,752 | +$3,492,338 | +23.57% | |
| Ubs Group Ag | 0.00% | 699,352 | $14,630,444 | $18,078,249 | +$3,447,805 | +23.57% | |
| Vanguard Fiduciary Trust Co | 0.00% | 662,921 | $13,868,307 | $17,136,508 | +$3,268,201 | +23.57% | |
| Invesco Ltd. | 0.00% | 580,453 | $12,143,077 | $15,004,710 | +$2,861,633 | +23.57% | |
| Boothbay Fund Management, Llc | 0.28% | 571,350 | $11,952,642 | $14,769,398 | +$2,816,756 | +23.57% | |
| Congress Asset Management Co | 0.07% | 380,746 | $11,902,120 | $9,842,284 | -$2,059,836 | -17.31% | |
| Point72 Asset Management, L.P. | 0.02% | 533,937 | $11,169,962 | $13,802,271 | +$2,632,309 | +23.57% | |
| Assenagon Asset Management S.A. | 0.01% | 345,156 | $10,789,577 | $8,922,283 | -$1,867,294 | -17.31% | |
| Ameriprise Financial Inc | 0.00% | 506,158 | $10,588,826 | $13,084,184 | +$2,495,358 | +23.57% | |
| Seven Fleet Capital Management Lp | 3.33% | 502,012 | $10,502,091 | $12,977,010 | +$2,474,919 | +23.57% | |
| Dimensional Fund Advisors Lp | 0.00% | 489,348 | $10,237,159 | $12,649,646 | +$2,412,487 | +23.57% | |
| Integral Health Asset Management, Llc | 0.50% | 450,000 | $9,414,000 | $11,632,500 | +$2,218,500 | +23.57% | |
| Soleus Capital Management, L.P. | 0.38% | 450,000 | $9,414,000 | $11,632,500 | +$2,218,500 | +23.57% | |
| Acuta Capital Partners, Llc | 6.57% | 441,831 | $9,243,105 | $11,421,331 | +$2,178,226 | +23.57% | |
| Millennium Management Llc | 0.01% | 425,644 | $8,904,472 | $11,002,897 | +$2,098,425 | +23.57% | |
| Pfm Health Sciences, Lp | 0.89% | 406,245 | $8,498,645 | $10,501,433 | +$2,002,788 | +23.57% |
Frequently asked questions about TNGX
Who owns the most TNGX stock?
The largest holders of TNGX are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for TANGO THERAPEUTICS INC (TNGX).
Is TNGX widely held by superinvestors?
Many widely followed stocks like TNGX appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly TNGX is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.