TNGX Institutional Ownership & Shareholders
TANGO THERAPEUTICS INC (TNGX) is currently held by 241 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $6.00B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Rtw Investments, Lp is currently the largest disclosed institutional shareholder of TNGX tracked by InsiderSet, reporting ownership valued at approximately $434.53M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $315.82M, representing an estimated loss of -27.32% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 49% of the total disclosed TNGX value among the investors covered in this analysis. Major shareholders include Rtw Investments, Lp, Blackrock, Inc., Fmr Llc, and several other long-term asset managers with concentrated positions in TANGO THERAPEUTICS INC (TNGX).
This page ranks the largest institutional TNGX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
241
Total Reported Value
$6.00B
Largest Holder
Rtw Investments, Lp
Largest Position
$434.53M
Insider Transactions (90d)
10
Latest Filing Quarter
Q2 2026
New Institutional Positions
94
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Rtw Investments, Lp | 3.71% | 13,900,620 | $434,533,381 | $315,822,086 | -$118,711,295 | -27.32% | |
| Blackrock, Inc. | 0.01% | 12,438,444 | $388,825,760 | $282,601,448 | -$106,224,312 | -27.32% | |
| Fmr Llc | 0.02% | 12,333,339 | $385,540,161 | $280,213,462 | -$105,326,699 | -27.32% | |
| Boxer Capital Management, Llc | 25.61% | 10,876,219 | $339,990,606 | $247,107,696 | -$92,882,910 | -27.32% | |
| Goldman Sachs Group Inc | 0.03% | 9,980,620 | $311,994,191 | $226,759,686 | -$85,234,505 | -27.32% | |
| Tcg Crossover Management, Llc | 6.82% | 9,081,201 | $283,878,343 | $206,324,887 | -$77,553,456 | -27.32% | |
| Paradigm Biocapital Advisors Lp | 3.72% | 6,357,523 | $198,736,169 | $144,442,923 | -$54,293,246 | -27.32% | |
| Price T Rowe Associates Inc | 0.02% | 6,348,827 | $198,465,000 | $144,245,349 | -$54,219,651 | -27.32% | |
| Siren, L.L.C. | 3.92% | 6,179,364 | $193,166,919 | $140,395,150 | -$52,771,769 | -27.32% | |
| State Street Corp | 0.01% | 5,979,806 | $186,928,736 | $135,861,192 | -$51,067,544 | -27.32% | |
| Vanguard Capital Management Llc | 0.00% | 5,957,348 | $186,226,699 | $135,350,947 | -$50,875,752 | -27.32% | |
| Adage Capital Partners Gp, L.L.C. | 0.25% | 5,600,000 | $175,056,000 | $127,232,000 | -$47,824,000 | -27.32% | |
| Deep Track Capital, Lp | 1.93% | 4,200,000 | $131,292,000 | $95,424,000 | -$35,868,000 | -27.32% | |
| Deerfield Management Company, L.P. | 1.37% | 4,190,611 | $130,998,500 | $95,210,682 | -$35,787,818 | -27.32% | |
| Woodline Partners Lp | 0.39% | 4,000,567 | $125,057,724 | $90,892,882 | -$34,164,842 | -27.32% | |
| Trv Gp Iv, Llc | 47.37% | 6,374,574 | $120,181,383 | $144,830,321 | +$24,648,938 | +20.51% | |
| Geode Capital Management, Llc | 0.01% | 3,742,791 | $117,021,411 | $85,036,212 | -$31,985,199 | -27.33% | |
| Perceptive Advisors Llc | 1.64% | 3,377,000 | $105,565,020 | $76,725,440 | -$28,839,580 | -27.32% | |
| Seven Fleet Capital Management Lp | 15.79% | 3,228,144 | $95,660,985 | $73,343,432 | -$22,317,553 | -23.33% | |
| Logos Global Management Lp | 3.84% | 2,850,000 | $89,091,000 | $64,752,000 | -$24,339,000 | -27.32% | |
| Caligan Partners Lp | 3.77% | 2,500,103 | $78,153,220 | $56,802,340 | -$21,350,880 | -27.32% | |
| Holocene Advisors, Lp | 0.17% | 2,410,939 | $75,365,953 | $54,776,534 | -$20,589,419 | -27.32% | |
| Commodore Capital Lp | 4.19% | 2,250,000 | $70,335,000 | $51,120,000 | -$19,215,000 | -27.32% | |
| Balyasny Asset Management L.P. | 0.12% | 2,016,379 | $63,032,008 | $45,812,131 | -$17,219,877 | -27.32% | |
| Jefferies Financial Group Inc. | 0.58% | 2,010,534 | $62,849,293 | $45,679,332 | -$17,169,961 | -27.32% | |
| Candriam S.C.A. | 0.23% | 1,630,553 | $50,922,046 | $37,046,164 | -$13,875,882 | -27.25% | |
| Janus Henderson Group Plc | 0.02% | 2,394,972 | $50,066,890 | $54,413,764 | +$4,346,874 | +8.68% | |
| Vanguard Portfolio Management Llc | 0.00% | 1,585,111 | $49,550,570 | $36,013,722 | -$13,536,848 | -27.32% | |
| Jpmorgan Chase & Co | 0.00% | 1,418,193 | $46,318,195 | $32,221,345 | -$14,096,850 | -30.43% | |
| Polar Capital Holdings Plc | 0.13% | 1,480,740 | $46,287,932 | $33,642,413 | -$12,645,519 | -27.32% | |
| Vivo Capital, Llc | 3.94% | 1,379,769 | $43,131,579 | $31,348,352 | -$11,783,227 | -27.32% | |
| Cormorant Asset Management, Lp | 2.08% | 1,300,000 | $40,638,000 | $29,536,000 | -$11,102,000 | -27.32% | |
| Northern Trust Corp | 0.00% | 1,231,933 | $38,510,226 | $27,989,518 | -$10,520,708 | -27.32% | |
| Stempoint Capital Lp | 6.62% | 1,223,019 | $38,231,574 | $27,786,992 | -$10,444,582 | -27.32% | |
| Federated Hermes, Inc. | 0.05% | 1,214,613 | $37,968,802 | $27,596,007 | -$10,372,795 | -27.32% | |
| Voya Investment Management Llc | 0.03% | 1,103,030 | $34,480,718 | $25,060,842 | -$9,419,876 | -27.32% | |
| Charles Schwab Investment Management Inc | 0.00% | 1,072,059 | $33,512,564 | $24,357,180 | -$9,155,384 | -27.32% | |
| American Century Companies Inc | 0.01% | 1,013,794 | $31,691,245 | $23,033,400 | -$8,657,845 | -27.32% | |
| Integral Health Asset Management, Llc | 1.28% | 1,000,000 | $31,260,000 | $22,720,000 | -$8,540,000 | -27.32% | |
| Vanguard Fiduciary Trust Co | 0.01% | 915,565 | $28,620,562 | $20,801,637 | -$7,818,925 | -27.32% | |
| Nuveen, Llc | 0.01% | 890,170 | $27,826,714 | $20,224,662 | -$7,602,052 | -27.32% | |
| Samlyn Capital, Llc | 0.40% | 766,473 | $23,959,946 | $17,414,267 | -$6,545,679 | -27.32% | |
| Renaissance Technologies LLC | Jim Simons | 0.03% | 748,300 | $23,391,858 | $17,001,376 | -$6,390,482 | -27.32% |
| Soleus Capital Management, L.P. | 0.76% | 709,000 | $22,163,340 | $16,108,480 | -$6,054,860 | -27.32% | |
| Arrowmark Colorado Holdings Llc | 0.92% | 708,385 | $22,144,115 | $16,094,507 | -$6,049,608 | -27.32% | |
| Bellevue Group Ag | 0.46% | 694,182 | $21,700,129 | $15,771,815 | -$5,928,314 | -27.32% | |
| Alyeska Investment Group, L.P. | 0.06% | 691,109 | $21,604,067 | $15,701,996 | -$5,902,071 | -27.32% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.04% | 636,070 | $19,883,549 | $14,451,510 | -$5,432,039 | -27.32% | |
| Bank Of America Corp | 0.00% | 600,834 | $18,782,070 | $13,650,948 | -$5,131,122 | -27.32% | |
| Pictet Asset Management Holding Sa | 0.02% | 582,262 | $18,343,379 | $13,228,993 | -$5,114,386 | -27.88% |
Frequently asked questions about TNGX
Who are the largest institutional holders of TNGX?
The largest institutional holders of TNGX reported in the latest SEC Form 13F filings include Rtw Investments, Lp, Blackrock, Inc., Fmr Llc, Boxer Capital Management, Llc, and Goldman Sachs Group Inc. InsiderSet ranks institutional holders by their latest reported TNGX position.
What is TNGX institutional ownership?
This page tracks TNGX positions reported by institutional investment managers through SEC Form 13F. TANGO THERAPEUTICS INC (TNGX) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own TNGX?
InsiderSet currently tracks 241 institutional managers reporting TNGX holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of TNGX shareholders.
How much TNGX stock do institutions own?
Institutional investment managers disclosed approximately $6.00B in TNGX holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was TNGX institutional ownership last updated?
The latest TNGX institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional TNGX holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its TNGX position after the reporting date.
Are institutions buying or selling TNGX?
Institutional buying and selling can be analyzed by comparing TNGX positions across consecutive 13F reporting periods. InsiderSet's TNGX Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View TNGX ownership changes.
How has TNGX institutional ownership changed over time?
InsiderSet tracks TNGX institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.