ANNEXON INC (ANNX) Top Institutional Shareholders
ANNEXON INC (ANNX) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $854.14M in ANNX holdings during the latest filing period.
Redmile Group, Llc is currently the largest disclosed institutional shareholder of ANNX tracked by InsiderSet, reporting ownership valued at approximately $80.61M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $71.88M, representing an estimated loss of -10.83% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 50% of the total disclosed ANNX value among the investors covered in this analysis. Major shareholders include Redmile Group, Llc, Blackrock, Inc., Fmr Llc, and several other long-term asset managers with concentrated positions in ANNEXON INC (ANNX).
This page ranks the largest institutional ANNX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
215
Total Reported Value
$854.14M
Largest Holder
Redmile Group, Llc
Largest Position
$80.61M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
166
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Redmile Group, Llc | 5.34% | 14,549,768 | $80,605,715 | $71,875,854 | -$8,729,861 | -10.83% | |
| Blackrock, Inc. | 0.00% | 10,938,509 | $60,599,340 | $54,036,234 | -$6,563,106 | -10.83% | |
| Fmr Llc | 0.00% | 10,635,648 | $58,921,492 | $52,540,101 | -$6,381,391 | -10.83% | |
| Bvf Inc/Il | 1.54% | 8,698,173 | $48,187,878 | $42,968,975 | -$5,218,903 | -10.83% | |
| State Street Corp | 0.00% | 6,919,255 | $38,332,673 | $34,181,120 | -$4,151,553 | -10.83% | |
| Vanguard Capital Management Llc | 0.00% | 5,956,589 | $32,999,503 | $29,425,550 | -$3,573,953 | -10.83% | |
| Bain Capital Life Sciences Investors, Llc | 2.60% | 5,212,674 | $28,878,214 | $25,750,610 | -$3,127,604 | -10.83% | |
| Bellevue Group Ag | 0.68% | 5,157,290 | $28,571,387 | $25,477,013 | -$3,094,374 | -10.83% | |
| Mak Capital One Llc | 4.33% | 4,724,043 | $26,171,198 | $23,336,772 | -$2,834,426 | -10.83% | |
| Adage Capital Partners Gp, L.L.C. | 0.04% | 4,300,000 | $23,822,000 | $21,242,000 | -$2,580,000 | -10.83% | |
| Bank Of America Corp | 0.00% | 4,259,995 | $23,600,372 | $21,044,375 | -$2,555,997 | -10.83% | |
| Nuveen, Llc | 0.01% | 4,246,330 | $23,524,668 | $20,976,870 | -$2,547,798 | -10.83% | |
| Siren, L.L.C. | 0.61% | 3,958,646 | $21,930,899 | $19,555,711 | -$2,375,188 | -10.83% | |
| Balyasny Asset Management L.P. | 0.04% | 3,886,909 | $21,533,476 | $19,201,330 | -$2,332,146 | -10.83% | |
| Ameriprise Financial Inc | 0.00% | 3,449,121 | $19,108,132 | $17,038,658 | -$2,069,474 | -10.83% | |
| Geode Capital Management, Llc | 0.00% | 3,377,823 | $18,717,903 | $16,686,446 | -$2,031,457 | -10.85% | |
| Qube Research & Technologies Ltd | 0.02% | 3,114,314 | $17,253,300 | $15,384,711 | -$1,868,589 | -10.83% | |
| Palo Alto Investors Lp | 2.50% | 2,948,090 | $16,332,419 | $14,563,565 | -$1,768,854 | -10.83% | |
| Morgan Stanley | 0.00% | 2,735,970 | $15,157,274 | $13,515,692 | -$1,641,582 | -10.83% | |
| Great Point Partners Llc | 3.39% | 2,500,000 | $13,850,000 | $12,350,000 | -$1,500,000 | -10.83% | |
| Woodline Partners Lp | 0.05% | 2,337,137 | $12,947,739 | $11,545,457 | -$1,402,282 | -10.83% | |
| Opaleye Management Inc. | 1.70% | 2,331,761 | $12,917,956 | $11,518,899 | -$1,399,057 | -10.83% | |
| Goldman Sachs Group Inc | 0.00% | 2,152,880 | $11,926,955 | $10,635,227 | -$1,291,728 | -10.83% | |
| Point72 Asset Management, L.P. | 0.02% | 1,871,795 | $10,369,744 | $9,246,667 | -$1,123,077 | -10.83% | |
| Vanguard Portfolio Management Llc | 0.00% | 1,483,090 | $8,216,319 | $7,326,465 | -$889,854 | -10.83% | |
| Y-Intercept (Hong Kong) Ltd | 0.14% | 1,319,913 | $7,312,318 | $6,520,370 | -$791,948 | -10.83% | |
| Tetragon Partners Gp Ltd | 1.41% | 1,292,455 | $7,160,201 | $6,384,728 | -$775,473 | -10.83% | |
| Ubs Group Ag | 0.00% | 1,245,941 | $6,902,513 | $6,154,949 | -$747,564 | -10.83% | |
| Millennium Management Llc | 0.01% | 1,238,678 | $6,862,276 | $6,119,069 | -$743,207 | -10.83% | |
| Charles Schwab Investment Management Inc | 0.00% | 1,102,445 | $6,107,545 | $5,446,078 | -$661,467 | -10.83% | |
| Northern Trust Corp | 0.00% | 1,086,902 | $6,021,437 | $5,369,296 | -$652,141 | -10.83% | |
| Dimensional Fund Advisors Lp | 0.00% | 924,078 | $5,115,464 | $4,564,945 | -$550,519 | -10.76% | |
| Kennedy Capital Management Llc | 0.11% | 912,323 | $5,054,269 | $4,506,876 | -$547,393 | -10.83% | |
| Massachusetts Financial Services Co | 0.00% | 903,368 | $5,004,659 | $4,462,638 | -$542,021 | -10.83% | |
| Vanguard Fiduciary Trust Co | 0.00% | 888,552 | $4,922,578 | $4,389,447 | -$533,131 | -10.83% | |
| Marshall Wace, Llp | 0.01% | 861,475 | $4,772,573 | $4,255,687 | -$516,887 | -10.83% | |
| Aqr Capital Management Llc | 0.00% | 777,253 | $4,305,982 | $3,839,630 | -$466,352 | -10.83% | |
| Invesco Ltd. | 0.00% | 763,005 | $4,227,048 | $3,769,245 | -$457,803 | -10.83% | |
| Russell Investments Group, Ltd. | 0.00% | 711,380 | $3,941,045 | $3,514,217 | -$426,828 | -10.83% | |
| D. E. Shaw & Co., Inc. | 0.00% | 702,799 | $3,893,507 | $3,471,827 | -$421,680 | -10.83% | |
| Wells Fargo & Company/Mn | 0.00% | 698,739 | $3,871,014 | $3,451,771 | -$419,243 | -10.83% | |
| Parkman Healthcare Partners Llc | 0.39% | 674,013 | $3,734,032 | $3,329,624 | -$404,408 | -10.83% | |
| Ensign Peak Advisors, Inc | 0.01% | 625,097 | $3,463,037 | $3,087,979 | -$375,058 | -10.83% | |
| Longaeva Partners L.P. | 0.17% | 620,401 | $3,437,022 | $3,064,781 | -$372,241 | -10.83% | |
| Citadel Advisors Llc | 0.00% | 600,135 | $3,324,747 | $2,964,667 | -$360,080 | -10.83% | |
| Deerfield Management Company, L.P. | 0.04% | 583,913 | $3,234,878 | $2,884,530 | -$350,348 | -10.83% | |
| Ikarian Capital, Llc | 0.46% | 580,244 | $3,214,551 | $2,866,405 | -$348,146 | -10.83% | |
| Sirios Capital Management L P | 0.39% | 575,063 | $3,185,849 | $2,840,811 | -$345,038 | -10.83% | |
| Deutsche Bank Ag\ | 0.00% | 562,181 | $3,114,483 | $2,777,174 | -$337,309 | -10.83% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 544,300 | $3,015,422 | $2,688,842 | -$326,580 | -10.83% |
Frequently asked questions about ANNX
Who owns the most ANNX stock?
The largest holders of ANNX are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ANNEXON INC (ANNX).
Is ANNX widely held by superinvestors?
Many widely followed stocks like ANNX appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ANNX is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.