ANNEXON INC (ANNX) Institutional Shareholders
ANNEXON INC (ANNX) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $1.02B in ANNX holdings during the latest filing period.
Fmr Llc is currently the largest disclosed institutional shareholder of ANNX tracked by InsiderSet, reporting ownership valued at approximately $111.45M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $82.56M, representing an estimated loss of -25.92% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 52% of the total disclosed ANNX value among the investors covered in this analysis. Major shareholders include Fmr Llc, Blackrock, Inc., Redmile Group, Llc, and several other long-term asset managers with concentrated positions in ANNEXON INC (ANNX).
This page ranks the largest institutional ANNX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
213
Total Reported Value
$1.02B
Largest Holder
Fmr Llc
Largest Position
$111.45M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
74
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Fmr Llc | 0.00% | 19,518,496 | $111,450,614 | $82,563,238 | -$28,887,376 | -25.92% | |
| Blackrock, Inc. | 0.00% | 13,539,744 | $77,311,938 | $57,273,117 | -$20,038,821 | -25.92% | |
| Redmile Group, Llc | 4.55% | 11,869,877 | $67,776,998 | $50,209,580 | -$17,567,418 | -25.92% | |
| State Street Corp | 0.00% | 9,824,321 | $56,096,873 | $41,556,878 | -$14,539,995 | -25.92% | |
| Bvf Inc/Il | 1.27% | 8,698,173 | $49,666,568 | $36,793,272 | -$12,873,296 | -25.92% | |
| Woodline Partners Lp | 0.12% | 6,925,067 | $39,542,133 | $29,293,033 | -$10,249,100 | -25.92% | |
| Vanguard Capital Management Llc | 0.00% | 6,871,015 | $39,233,496 | $29,064,393 | -$10,169,103 | -25.92% | |
| Mak Capital One Llc | 4.69% | 5,862,180 | $33,473,048 | $24,797,021 | -$8,676,027 | -25.92% | |
| Goldman Sachs Group Inc | 0.00% | 5,825,579 | $33,264,057 | $24,642,199 | -$8,621,858 | -25.92% | |
| Siren, L.L.C. | 0.52% | 4,458,646 | $25,458,869 | $18,860,073 | -$6,598,796 | -25.92% | |
| Bain Capital Life Sciences Investors, Llc | 1.51% | 4,437,731 | $25,339,444 | $18,771,602 | -$6,567,842 | -25.92% | |
| Bellevue Group Ag | 0.49% | 4,100,016 | $23,411,091 | $17,343,068 | -$6,068,023 | -25.92% | |
| Geode Capital Management, Llc | 0.00% | 4,037,193 | $23,056,071 | $17,077,326 | -$5,978,745 | -25.93% | |
| Mpm Bioimpact Llc | 1.23% | 3,544,354 | $20,238,261 | $14,992,617 | -$5,245,644 | -25.92% | |
| Ameriprise Financial Inc | 0.00% | 3,509,623 | $20,039,948 | $14,845,705 | -$5,194,243 | -25.92% | |
| Adage Capital Partners Gp, L.L.C. | 0.03% | 3,500,000 | $19,985,000 | $14,805,000 | -$5,180,000 | -25.92% | |
| Great Point Partners Llc | 4.71% | 3,500,000 | $19,985,000 | $14,805,000 | -$5,180,000 | -25.92% | |
| Morgan Stanley | 0.00% | 3,144,453 | $17,954,827 | $13,301,036 | -$4,653,791 | -25.92% | |
| Palo Alto Investors Lp | 2.33% | 2,948,090 | $16,833,594 | $12,470,421 | -$4,363,173 | -25.92% | |
| Balyasny Asset Management L.P. | 0.03% | 2,830,976 | $16,164,873 | $11,975,028 | -$4,189,845 | -25.92% | |
| Nuveen, Llc | 0.00% | 2,765,080 | $15,788,607 | $11,696,288 | -$4,092,319 | -25.92% | |
| Qube Research & Technologies Ltd | 0.02% | 2,749,961 | $15,702,277 | $11,632,335 | -$4,069,942 | -25.92% | |
| Vanguard Portfolio Management Llc | 0.00% | 2,246,800 | $12,829,228 | $9,503,964 | -$3,325,264 | -25.92% | |
| Opaleye Management Inc. | 0.89% | 1,714,451 | $9,789,515 | $7,252,128 | -$2,537,387 | -25.92% | |
| Logos Global Management Lp | 0.37% | 1,500,000 | $8,565,000 | $6,345,000 | -$2,220,000 | -25.92% | |
| Dimensional Fund Advisors Lp | 0.00% | 1,497,756 | $8,550,585 | $6,335,508 | -$2,215,077 | -25.91% | |
| Point72 Asset Management, L.P. | 0.01% | 1,382,699 | $7,895,211 | $5,848,817 | -$2,046,394 | -25.92% | |
| Northern Trust Corp | 0.00% | 1,352,046 | $7,720,182 | $5,719,155 | -$2,001,027 | -25.92% | |
| Charles Schwab Investment Management Inc | 0.00% | 1,257,799 | $7,182,032 | $5,320,490 | -$1,861,542 | -25.92% | |
| Tetragon Partners Gp Ltd | 1.15% | 1,242,455 | $7,094,418 | $5,255,585 | -$1,838,833 | -25.92% | |
| Candriam S.C.A. | 0.03% | 1,195,142 | $6,817,695 | $5,055,451 | -$1,762,244 | -25.85% | |
| Millennium Management Llc | 0.00% | 1,184,931 | $6,765,956 | $5,012,258 | -$1,753,698 | -25.92% | |
| Vanguard Fiduciary Trust Co | 0.00% | 1,105,450 | $6,312,120 | $4,676,054 | -$1,636,066 | -25.92% | |
| Massachusetts Financial Services Co | 0.00% | 1,037,366 | $5,923,360 | $4,388,058 | -$1,535,302 | -25.92% | |
| Jpmorgan Chase & Co | 0.00% | 1,004,308 | $5,593,995 | $4,248,223 | -$1,345,772 | -24.06% | |
| Wells Fargo & Company/Mn | 0.00% | 978,055 | $5,584,694 | $4,137,173 | -$1,447,521 | -25.92% | |
| Panagora Asset Management Inc | 0.02% | 967,926 | $5,526,857 | $4,094,327 | -$1,432,530 | -25.92% | |
| Kennedy Capital Management Llc | 0.09% | 898,394 | $5,129,830 | $3,800,207 | -$1,329,623 | -25.92% | |
| Ishara Investments Lp | 3.44% | 820,000 | $4,682,200 | $3,468,600 | -$1,213,600 | -25.92% | |
| Arrowstreet Capital, Limited Partnership | 0.00% | 737,935 | $4,213,609 | $3,121,465 | -$1,092,144 | -25.92% | |
| Y-Intercept (Hong Kong) Ltd | 0.08% | 734,585 | $4,194,480 | $3,107,295 | -$1,087,185 | -25.92% | |
| Russell Investments Group, Ltd. | 0.00% | 705,291 | $4,027,213 | $2,983,381 | -$1,043,832 | -25.92% | |
| Aqr Capital Management Llc | 0.00% | 691,812 | $3,950,245 | $2,926,365 | -$1,023,880 | -25.92% | |
| Parkman Healthcare Partners Llc | 0.38% | 641,029 | $3,660,276 | $2,711,553 | -$948,723 | -25.92% | |
| Acadian Asset Management Llc | 0.00% | 629,127 | $3,588,000 | $2,661,207 | -$926,793 | -25.83% | |
| Ubs Group Ag | 0.00% | 623,094 | $3,557,866 | $2,635,688 | -$922,178 | -25.92% | |
| Deutsche Bank Ag\ | 0.00% | 616,489 | $3,520,153 | $2,607,748 | -$912,405 | -25.92% | |
| Bank Of America Corp | 0.00% | 614,186 | $3,507,002 | $2,598,007 | -$908,995 | -25.92% | |
| Ensign Peak Advisors, Inc | 0.01% | 625,097 | $3,463,037 | $2,644,160 | -$818,877 | -23.65% | |
| Citadel Advisors Llc | 0.00% | 596,582 | $3,406,483 | $2,523,542 | -$882,941 | -25.92% |
Frequently asked questions about ANNX
Who owns the most ANNX stock?
The largest holders of ANNX are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ANNEXON INC (ANNX).
Is ANNX widely held by superinvestors?
Many widely followed stocks like ANNX appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ANNX is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.