AXSM Institutional Ownership & Shareholders
AXSOME THERAPEUTICS INC (AXSM) is currently held by 490 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $9.27B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Blackrock, Inc. is currently the largest disclosed institutional shareholder of AXSM tracked by InsiderSet, reporting ownership valued at approximately $759.69M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $422.14M, representing an estimated loss of -44.43% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 39% of the total disclosed AXSM value among the investors covered in this analysis. Major shareholders include Blackrock, Inc., Vanguard Portfolio Management Llc, Vanguard Capital Management Llc, and several other long-term asset managers with concentrated positions in AXSOME THERAPEUTICS INC (AXSM).
This page ranks the largest institutional AXSM shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
490
Total Reported Value
$9.27B
Largest Holder
Blackrock, Inc.
Largest Position
$759.69M
Insider Transactions (90d)
3
Latest Filing Quarter
Q2 2026
New Institutional Positions
75
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Blackrock, Inc. | 0.01% | 3,103,708 | $759,694,607 | $422,135,325 | -$337,559,282 | -44.43% | |
| Vanguard Portfolio Management Llc | 0.02% | 1,983,514 | $485,504,722 | $269,777,739 | -$215,726,983 | -44.43% | |
| Vanguard Capital Management Llc | 0.01% | 1,965,086 | $480,994,100 | $267,271,347 | -$213,722,753 | -44.43% | |
| Invesco Ltd. | 0.03% | 1,671,684 | $409,178,095 | $227,365,741 | -$181,812,354 | -44.43% | |
| Fmr Llc | 0.02% | 1,539,163 | $376,740,965 | $209,341,560 | -$167,399,405 | -44.43% | |
| Banque Cantonale Vaudoise | 0.04% | 1,269 | $311,000,000 | $172,597 | -$310,827,403 | -99.94% | |
| Geode Capital Management, Llc | 0.01% | 967,172 | $236,786,194 | $131,545,064 | -$105,241,130 | -44.45% | |
| Morgan Stanley | 0.01% | 804,082 | $196,815,434 | $109,363,193 | -$87,452,241 | -44.43% | |
| State Street Corp | 0.01% | 785,661 | $192,289,814 | $106,857,753 | -$85,432,061 | -44.43% | |
| Deep Track Capital, Lp | 2.52% | 700,000 | $171,339,000 | $95,207,000 | -$76,132,000 | -44.43% | |
| Two Sigma Investments, Lp | 0.12% | 669,478 | $163,868,130 | $91,055,703 | -$72,812,427 | -44.43% | |
| Wellington Management Group Llp | 0.03% | 653,920 | $160,059,998 | $88,939,659 | -$71,120,339 | -44.43% | |
| Alethea Capital Management, Llc | 65.78% | 648,756 | $158,796,006 | $88,237,304 | -$70,558,702 | -44.43% | |
| Price T Rowe Associates Inc | 0.02% | 642,893 | $157,362,000 | $87,439,877 | -$69,922,123 | -44.43% | |
| D. E. Shaw & Co., Inc. | 0.09% | 604,753 | $148,025,392 | $82,252,456 | -$65,772,936 | -44.43% | |
| Millennium Management Llc | 0.09% | 556,088 | $136,113,660 | $75,633,529 | -$60,480,131 | -44.43% | |
| Nomura Asset Management International Inc. | 0.20% | 539,407 | $132,031,000 | $73,364,746 | -$58,666,254 | -44.43% | |
| Norges Bank | 0.01% | 514,266 | $125,876,889 | $69,945,319 | -$55,931,570 | -44.43% | |
| First Trust Advisors Lp | 0.07% | 482,061 | $117,994,070 | $65,565,117 | -$52,428,953 | -44.43% | |
| Bank Of America Corp | 0.01% | 452,491 | $110,756,330 | $61,543,301 | -$49,213,029 | -44.43% | |
| Ameriprise Financial Inc | 0.02% | 428,079 | $104,781,493 | $58,223,025 | -$46,558,468 | -44.43% | |
| Qube Research & Technologies Ltd | 0.12% | 426,336 | $104,354,263 | $57,985,959 | -$46,368,304 | -44.43% | |
| Point72 Asset Management, L.P. | 0.16% | 416,516 | $101,950,621 | $56,650,341 | -$45,300,280 | -44.43% | |
| Jane Street Group, Llc | 0.06% | 403,995 | $98,885,856 | $54,947,360 | -$43,938,496 | -44.43% | |
| Hood River Capital Management Llc | 0.71% | 402,678 | $98,563,494 | $54,768,235 | -$43,795,259 | -44.43% | |
| Healthcare Of Ontario Pension Plan Trust Fund | 0.13% | 373,067 | $91,315,610 | $50,740,843 | -$40,574,767 | -44.43% | |
| Driehaus Capital Management Llc | 0.53% | 372,474 | $91,170,461 | $50,660,189 | -$40,510,272 | -44.43% | |
| Pictet Asset Management Holding Sa | 0.08% | 481,524 | $88,788,730 | $65,492,079 | -$23,296,651 | -26.24% | |
| Eventide Asset Management, Llc | 1.04% | 316,820 | $77,534,680 | $43,090,688 | -$34,443,992 | -44.42% | |
| Charles Schwab Investment Management Inc | 0.01% | 316,104 | $77,372,776 | $42,993,305 | -$34,379,471 | -44.43% | |
| Integral Health Asset Management, Llc | 3.01% | 300,000 | $73,431,000 | $40,803,000 | -$32,628,000 | -44.43% | |
| Vanguard Fiduciary Trust Co | 0.02% | 279,738 | $68,471,470 | $38,047,165 | -$30,424,305 | -44.43% | |
| Northern Trust Corp | 0.01% | 270,189 | $66,134,161 | $36,748,406 | -$29,385,755 | -44.43% | |
| Renaissance Technologies LLC | Jim Simons | 0.09% | 262,000 | $64,129,740 | $35,634,620 | -$28,495,120 | -44.43% |
| Adage Capital Partners Gp, L.L.C. | 0.09% | 259,034 | $63,403,752 | $35,231,214 | -$28,172,538 | -44.43% | |
| Citadel Advisors Llc | 0.04% | 255,878 | $62,631,258 | $34,801,967 | -$27,829,291 | -44.43% | |
| Frontier Capital Management Co Llc | 0.58% | 254,280 | $62,240,116 | $34,584,623 | -$27,655,493 | -44.43% | |
| Samlyn Capital, Llc | 1.00% | 246,015 | $60,217,091 | $33,460,500 | -$26,756,591 | -44.43% | |
| Clearbridge Investments, Llc | 0.05% | 245,574 | $60,109,141 | $33,400,520 | -$26,708,621 | -44.43% | |
| Loomis Sayles & Co L P | 0.07% | 239,490 | $58,619,967 | $32,573,035 | -$26,046,932 | -44.43% | |
| Principal Financial Group Inc | 0.03% | 310,080 | $57,175,650 | $42,173,981 | -$15,001,669 | -26.24% | |
| Bnp Paribas Financial Markets | 0.03% | 230,954 | $56,530,611 | $31,412,054 | -$25,118,557 | -44.43% | |
| Goldman Sachs Group Inc | 0.01% | 229,668 | $56,215,836 | $31,237,145 | -$24,978,691 | -44.43% | |
| Canada Pension Plan Investment Board | 0.03% | 225,400 | $55,171,158 | $30,656,654 | -$24,514,504 | -44.43% | |
| Marshall Wace, Llp | 0.05% | 223,386 | $54,678,192 | $30,382,730 | -$24,295,462 | -44.43% | |
| Pfm Health Sciences, Lp | 4.67% | 219,596 | $53,750,513 | $29,867,252 | -$23,883,261 | -44.43% | |
| Tri Locum Partners Lp | 6.60% | 219,308 | $53,680,019 | $29,828,081 | -$23,851,938 | -44.43% | |
| First Turn Management, Llc | 5.72% | 218,415 | $53,461,440 | $29,706,624 | -$23,754,816 | -44.43% | |
| Bank Of New York Mellon Corp | 0.01% | 197,226 | $48,274,913 | $26,824,708 | -$21,450,205 | -44.43% | |
| Nuveen, Llc | 0.01% | 190,080 | $46,525,881 | $25,852,781 | -$20,673,100 | -44.43% |
Frequently asked questions about AXSM
Who are the largest institutional holders of AXSM?
The largest institutional holders of AXSM reported in the latest SEC Form 13F filings include Blackrock, Inc., Vanguard Portfolio Management Llc, Vanguard Capital Management Llc, Invesco Ltd., and Fmr Llc. InsiderSet ranks institutional holders by their latest reported AXSM position.
What is AXSM institutional ownership?
This page tracks AXSM positions reported by institutional investment managers through SEC Form 13F. AXSOME THERAPEUTICS INC (AXSM) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own AXSM?
InsiderSet currently tracks 490 institutional managers reporting AXSM holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of AXSM shareholders.
How much AXSM stock do institutions own?
Institutional investment managers disclosed approximately $9.27B in AXSM holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was AXSM institutional ownership last updated?
The latest AXSM institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional AXSM holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its AXSM position after the reporting date.
Are institutions buying or selling AXSM?
Institutional buying and selling can be analyzed by comparing AXSM positions across consecutive 13F reporting periods. InsiderSet's AXSM Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View AXSM ownership changes.
How has AXSM institutional ownership changed over time?
InsiderSet tracks AXSM institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.