FRACTYL HEALTH INC (GUTS) Institutional Ownership Changes & 13F Activity
FRACTYL HEALTH INC (GUTS). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include 683 Capital Management, Llc, Woodline Partners Lp, Catalio Capital Management, Lp, General Catalyst Group Management, Llc, and Deer Management Co. Llc.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Catalio Capital Management, Lp | Buy | +5,491,866 | — | 5,491,866 | $12.08M | Q4 2025 | Sep 02, 2026 |
| Virtu Financial Llc | Buy | +69,427 | — | 69,427 | $153.00K | Q4 2025 | Feb 23, 2026 |
| Ikarian Capital, Llc | Buy | +1,100,000 | — | 1,100,000 | $2.42M | Q4 2025 | Feb 18, 2026 |
| Raymond James Financial Inc | Buy | +15,074 | — | 15,074 | $33.16K | Q4 2025 | Feb 18, 2026 |
| 683 Capital Management, Llc | Buy | +6,047,620 | — | 6,047,620 | $13.30M | Q4 2025 | Feb 17, 2026 |
| Woodline Partners Lp | Buy | +5,506,771 | — | 5,506,771 | $12.11M | Q4 2025 | Feb 17, 2026 |
| General Catalyst Group Management, Llc | Buy | +4,884,193 | — | 4,884,193 | $10.75M | Q4 2025 | Feb 17, 2026 |
| Deer Management Co. Llc | Buy | +4,770,901 | — | 4,770,901 | $10.50M | Q4 2025 | Feb 17, 2026 |
| Atom Investors Lp | Buy | +1,883,018 | — | 1,883,018 | $4.14M | Q4 2025 | Feb 17, 2026 |
| Millennium Management Llc | Buy | +1,861,418 | — | 1,861,418 | $4.10M | Q4 2025 | Feb 17, 2026 |
| Two Sigma Investments, Lp | Buy | +1,840,136 | — | 1,840,136 | $4.05M | Q4 2025 | Feb 17, 2026 |
| D. E. Shaw & Co., Inc. | Buy | +1,442,745 | — | 1,442,745 | $3.17M | Q4 2025 | Feb 17, 2026 |
| Two Sigma Advisers, Lp | Buy | +1,298,700 | — | 1,298,700 | $2.86M | Q4 2025 | Feb 17, 2026 |
| Bank Of America Corp | Buy | +1,192,236 | — | 1,192,236 | $2.62M | Q4 2025 | Feb 17, 2026 |
| Newtyn Management, Llc | Buy | +1,134,021 | — | 1,134,021 | $2.49M | Q4 2025 | Feb 17, 2026 |
| Logos Global Management Lp | Buy | +1,100,000 | — | 1,100,000 | $2.42M | Q4 2025 | Feb 17, 2026 |
| Susquehanna International Group, Llp | Buy | +799,457 | — | 799,457 | $1.76M | Q4 2025 | Feb 17, 2026 |
| Burkehill Global Management, Lp | Buy | +500,000 | — | 500,000 | $1.10M | Q4 2025 | Feb 17, 2026 |
| Brevan Howard Capital Management Lp | Buy | +464,738 | — | 464,738 | $1.05M | Q4 2025 | Feb 17, 2026 |
| Point72 Asset Management, L.P. | Buy | +365,173 | — | 365,173 | $803.38K | Q4 2025 | Feb 17, 2026 |
| Quadrature Capital Ltd | Buy | +290,714 | — | 290,714 | $639.57K | Q4 2025 | Feb 17, 2026 |
| Boothbay Fund Management, Llc | Buy | +275,219 | — | 275,219 | $605.48K | Q4 2025 | Feb 17, 2026 |
| Citadel Advisors Llc | Buy | +228,985 | — | 228,985 | $503.77K | Q4 2025 | Feb 17, 2026 |
| Northern Trust Corp | Buy | +215,877 | — | 215,877 | $474.93K | Q4 2025 | Feb 17, 2026 |
| Exoduspoint Capital Management, Lp | Buy | +178,024 | — | 178,024 | $391.65K | Q4 2025 | Feb 17, 2026 |
| Shay Capital Llc | Buy | +136,568 | — | 136,568 | $300.45K | Q4 2025 | Feb 17, 2026 |
| Qube Research & Technologies Ltd | Buy | +117,631 | — | 117,631 | $258.79K | Q4 2025 | Feb 17, 2026 |
| Prelude Capital Management, Llc | Buy | +80,597 | — | 80,597 | $177.31K | Q4 2025 | Feb 17, 2026 |
| Osaic Holdings, Inc. | Buy | +75,476 | — | 75,476 | $166.05K | Q4 2025 | Feb 17, 2026 |
| Balyasny Asset Management L.P. | Buy | +60,219 | — | 60,219 | $132.48K | Q4 2025 | Feb 17, 2026 |
Frequently asked questions about GUTS activity
Which institutional owners are buying GUTS?
Institutional owners buying GUTS include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in GUTS activity?
"Buy" means an investor increased their reported position in GUTS compared to the prior reporting period. This reflects growing exposure to FRACTYL HEALTH INC (GUTS) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in GUTS increasing?
Institutional interest in GUTS can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related GUTS Institutional Insights
- GUTS Overview
- GUTS 13F Institutional Holders
- GUTS Superinvestors
- Healthcare Sector Institutional Ownership
- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
- Most Bought Healthcare Stocks By Institutional Investors
- Most Sold Healthcare Stocks By Institutional Investors
- GUTS Insider Trading & SEC Form 4 Activity
- GUTS Articles
- Top Institutional Investor Stock Rankings