OMEROS CORP (OMER) Institutional Ownership Changes & 13F Activity

OMEROS CORP (OMER). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include D. E. Shaw & Co., Inc., Susquehanna International Group, Llp, Corient Private Wealth Llc, Nomura Holdings Inc, and Northern Trust Corp.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Strategic Investment Solutions, Inc.Buy+1,827—1,827$31.38KQ4 2025Feb 27, 2026
Corient Private Wealth LlcBuy+687,325—687,325$11.80MQ4 2025Feb 19, 2026
Raymond James Financial IncBuy+12,242—12,242$210.26KQ4 2025Feb 18, 2026
Newedge Advisors, LlcBuy+1,000—1,000$17.18KQ4 2025Feb 18, 2026
D. E. Shaw & Co., Inc.Buy+754,999—754,999$12.97MQ4 2025Feb 17, 2026
Susquehanna International Group, LlpBuy+741,895—741,895$12.74MQ4 2025Feb 17, 2026
Nomura Holdings IncBuy+655,021—655,021$11.25MQ4 2025Feb 17, 2026
Northern Trust CorpBuy+526,732—526,732$9.05MQ4 2025Feb 17, 2026
Two Sigma Investments, LpBuy+524,757—524,757$9.01MQ4 2025Feb 17, 2026
Royal Bank Of CanadaBuy+498,399—498,399$8.56MQ4 2025Feb 17, 2026
Millennium Management LlcBuy+441,811—441,811$7.59MQ4 2025Feb 17, 2026
Citadel Advisors LlcBuy+240,352—240,352$4.13MQ4 2025Feb 17, 2026
Jump Financial, LlcBuy+228,000—228,000$3.92MQ4 2025Feb 17, 2026
Wellington Management Group LlpBuy+202,617—202,617$3.48MQ4 2025Feb 17, 2026
Ameriprise Financial IncBuy+117,004—117,004$2.01MQ4 2025Feb 17, 2026
Bank Of America CorpBuy+114,808—114,808$1.97MQ4 2025Feb 17, 2026
Price T Rowe Associates IncBuy+95,745—95,745$1.64MQ4 2025Feb 17, 2026
Susquehanna Portfolio Strategies, LlcBuy+92,759—92,759$1.59MQ4 2025Feb 17, 2026
Two Sigma Advisers, LpBuy+76,100—76,100$1.31MQ4 2025Feb 17, 2026
Alliancebernstein L.P.Buy+73,490—73,490$1.26MQ4 2025Feb 17, 2026
Polar Asset Management Partners Inc.Buy+68,800—68,800$1.18MQ4 2025Feb 17, 2026
Brevan Howard Capital Management LpBuy+64,957—64,957$1.12MQ4 2025Feb 17, 2026
Ancora Advisors LlcBuy+59,250—59,250$1.02MQ4 2025Feb 17, 2026
Bridgeway Capital Management, LlcBuy+56,715—56,715$974.08KQ4 2025Feb 17, 2026
Mirae Asset Global Etfs Holdings Ltd.Buy+30,585—30,585$525.30KQ4 2025Feb 17, 2026
Man Group PlcBuy+27,099—27,099$465.43KQ4 2025Feb 17, 2026
Virtus Investment Advisers, LlcBuy+26,212—26,212$450.19KQ4 2025Feb 17, 2026
Quantinno Capital Management LpBuy+25,074—25,074$430.65KQ4 2025Feb 17, 2026
Adar1 Capital Management, LlcBuy+25,000—25,000$429.38KQ4 2025Feb 17, 2026
Aqr Capital Management LlcBuy+22,838—22,838$392.24KQ4 2025Feb 17, 2026
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Frequently asked questions about OMER activity

  • Which institutional owners are buying OMER?

    Institutional owners buying OMER include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in OMER activity?

    "Buy" means an investor increased their reported position in OMER compared to the prior reporting period. This reflects growing exposure to OMEROS CORP (OMER) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in OMER increasing?

    Institutional interest in OMER can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.