OPTIMIZERX CORP (OPRX) Institutional Ownership Changes & 13F Activity

OPTIMIZERX CORP (OPRX). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Rice Hall James & Associates, Llc, Blair William & Co/Il, Parkman Healthcare Partners Llc, Manatuck Hill Partners, Llc, and G2 Investment Partners Management Llc.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Independent Financial Group, LlcBuy+16,500—16,500$202.29KQ4 2025May 15, 2026
Sunbelt Securities, Inc.Buy+11—11$135.00Q4 2025Feb 20, 2026
Raymond James Financial IncBuy+82,414—82,414$1.01MQ4 2025Feb 18, 2026
Rice Hall James & Associates, LlcBuy+590,674—590,674$7.24MQ4 2025Feb 17, 2026
Blair William & Co/IlBuy+582,585—582,585$7.14MQ4 2025Feb 17, 2026
Parkman Healthcare Partners LlcBuy+538,649—538,649$6.60MQ4 2025Feb 17, 2026
Manatuck Hill Partners, LlcBuy+422,107—422,107$5.18MQ4 2025Feb 17, 2026
G2 Investment Partners Management LlcBuy+310,000—310,000$3.80MQ4 2025Feb 17, 2026
Russell Investments Group, Ltd.Buy+289,060—289,060$3.54MQ4 2025Feb 17, 2026
Northern Trust CorpBuy+156,927—156,927$1.92MQ4 2025Feb 17, 2026
Granahan Investment Management, LlcBuy+117,122—117,122$1.44MQ4 2025Feb 17, 2026
D. E. Shaw & Co., Inc.Buy+112,867—112,867$1.38MQ4 2025Feb 17, 2026
Schonfeld Strategic Advisors LlcBuy+98,170—98,170$1.20MQ4 2025Feb 17, 2026
Inspire Investing, LlcBuy+95,880—95,880$1.18MQ4 2025Feb 17, 2026
Credit Agricole S ABuy+89,200—89,200$1.09MQ4 2025Feb 17, 2026
Boothbay Fund Management, LlcBuy+73,488—73,488$900.96KQ4 2025Feb 17, 2026
Bridgeway Capital Management, LlcBuy+69,029—69,029$846.30KQ4 2025Feb 17, 2026
Qube Research & Technologies LtdBuy+59,161—59,161$725.31KQ4 2025Feb 17, 2026
State Of Wisconsin Investment BoardBuy+53,094—53,094$650.93KQ4 2025Feb 17, 2026
Two Sigma Investments, LpBuy+46,181—46,181$566.18KQ4 2025Feb 17, 2026
Millennium Management LlcBuy+43,669—43,669$535.38KQ4 2025Feb 17, 2026
Bank Of America CorpBuy+42,576—42,576$521.98KQ4 2025Feb 17, 2026
Alliancebernstein L.P.Buy+39,850—39,850$488.56KQ4 2025Feb 17, 2026
Susquehanna International Group, LlpBuy+29,741—29,741$364.63KQ4 2025Feb 17, 2026
Ameriprise Financial IncBuy+25,351—25,351$310.80KQ4 2025Feb 17, 2026
Engineers Gate Manager LpBuy+18,634—18,634$228.45KQ4 2025Feb 17, 2026
Quantinno Capital Management LpBuy+17,504—17,504$214.60KQ4 2025Feb 17, 2026
Aqr Capital Management LlcBuy+14,514—14,514$177.94KQ4 2025Feb 17, 2026
Canada Pension Plan Investment BoardBuy+13,900—13,900$170.41KQ4 2025Feb 17, 2026
Exoduspoint Capital Management, LpBuy+12,252—12,252$150.21KQ4 2025Feb 17, 2026
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Frequently asked questions about OPRX activity

  • Which institutional owners are buying OPRX?

    Institutional owners buying OPRX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in OPRX activity?

    "Buy" means an investor increased their reported position in OPRX compared to the prior reporting period. This reflects growing exposure to OPTIMIZERX CORP (OPRX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in OPRX increasing?

    Institutional interest in OPRX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.