Septerna, Inc. (SEPN) Institutional Ownership and Insiders Activity

Septerna, Inc. (SEPN) is widely held by institutional investors, with 151 firms reporting positions valued at approximately $1.41B based on SEC Form 13F filings for the quarter ended June 30, 2026.

Ra Capital Management, L.P. is the largest disclosed holder, reporting approximately $234.29M in SEPN holdings in its latest filing.

Recent insider activity includes 3 tracked Form 4 transactions over the last three months, reflecting ongoing executive and director trading activity.