SILENCE THERAPEUTICS PLC-ADR (SLN) Institutional Shareholders
SILENCE THERAPEUTICS PLC-ADR (SLN) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $238.66M in SLN holdings during the latest filing period.
Siren, L.L.C. is currently the largest disclosed institutional shareholder of SLN tracked by InsiderSet, reporting ownership valued at approximately $36.36M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $41.39M, representing an estimated gain of +13.84% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 69% of the total disclosed SLN value among the investors covered in this analysis. Major shareholders include Siren, L.L.C., Tcg Crossover Management, Llc, Redmile Group, Llc, and several other long-term asset managers with concentrated positions in SILENCE THERAPEUTICS PLC-ADR (SLN).
This page ranks the largest institutional SLN shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
71
Total Reported Value
$238.66M
Largest Holder
Siren, L.L.C.
Largest Position
$36.36M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
82
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Siren, L.L.C. | 0.74% | 3,311,438 | $36,359,589 | $41,392,975 | +$5,033,386 | +13.84% | |
| Tcg Crossover Management, Llc | 0.80% | 3,033,560 | $33,308,489 | $37,919,500 | +$4,611,011 | +13.84% | |
| Redmile Group, Llc | 1.60% | 2,164,777 | $23,769,251 | $27,059,713 | +$3,290,462 | +13.84% | |
| Nantahala Capital Management, Llc | 0.89% | 1,346,731 | $14,787,106 | $16,834,138 | +$2,047,032 | +13.84% | |
| Citadel Advisors Llc | 0.01% | 1,329,625 | $14,599,282 | $16,620,313 | +$2,021,031 | +13.84% | |
| Nextech Invest, Ltd. | 0.50% | 952,400 | $10,457,352 | $11,905,000 | +$1,447,648 | +13.84% | |
| Millennium Management Llc | 0.01% | 909,279 | $9,983,883 | $11,365,988 | +$1,382,105 | +13.84% | |
| Tetragon Partners Gp Ltd | 1.37% | 764,256 | $8,391,531 | $9,553,200 | +$1,161,669 | +13.84% | |
| Soleus Capital Management, L.P. | 0.24% | 630,000 | $6,917,400 | $7,875,000 | +$957,600 | +13.84% | |
| Balyasny Asset Management L.P. | 0.01% | 610,980 | $6,708,560 | $7,637,250 | +$928,690 | +13.84% | |
| 5Am Venture Management, Llc | 1.82% | 476,200 | $5,228,676 | $5,952,500 | +$723,824 | +13.84% | |
| Great Point Partners Llc | 1.16% | 450,000 | $4,941,000 | $5,625,000 | +$684,000 | +13.84% | |
| Morgan Stanley | 0.00% | 403,172 | $4,426,828 | $5,039,650 | +$612,822 | +13.84% | |
| Ameriprise Financial Inc | 0.00% | 370,052 | $4,063,171 | $4,625,650 | +$562,479 | +13.84% | |
| Jane Street Group, Llc | 0.00% | 369,151 | $4,053,278 | $4,614,388 | +$561,110 | +13.84% | |
| Adar1 Capital Management, Llc | 0.17% | 338,373 | $3,715,336 | $4,229,663 | +$514,327 | +13.84% | |
| Summittx Capital, L.P. | 0.09% | 326,648 | $3,586,595 | $4,083,100 | +$496,505 | +13.84% | |
| Schonfeld Strategic Advisors Llc | 0.02% | 269,348 | $2,957,439 | $3,366,850 | +$409,411 | +13.84% | |
| Ubs Group Ag | 0.00% | 243,152 | $2,669,809 | $3,039,400 | +$369,591 | +13.84% | |
| Ishara Investments Lp | 1.79% | 55,350 | $2,434,847 | $691,875 | -$1,742,972 | -71.58% | |
| Blackrock, Inc. | 0.00% | 219,917 | $2,414,689 | $2,748,963 | +$334,274 | +13.84% | |
| Bank Of Montreal | 0.00% | 201,734 | $2,215,039 | $2,521,675 | +$306,636 | +13.84% | |
| Boothbay Fund Management, Llc | 0.04% | 198,347 | $2,177,850 | $2,479,338 | +$301,488 | +13.84% | |
| Propel Bio Management, Llc | 1.10% | 191,733 | $2,105,228 | $2,396,663 | +$291,435 | +13.84% | |
| Susquehanna International Group, Llp | 0.00% | 184,519 | $2,026,019 | $2,306,488 | +$280,469 | +13.84% | |
| Fred Alger Management, Llc | 0.01% | 177,000 | $1,943,460 | $2,212,500 | +$269,040 | +13.84% | |
| Ikarian Capital, Llc | 0.30% | 830,784 | $1,827,725 | $10,384,800 | +$8,557,075 | +468.18% | |
| Qube Research & Technologies Ltd | 0.00% | 163,945 | $1,800,116 | $2,049,313 | +$249,197 | +13.84% | |
| Caption Management, Llc | 0.06% | 162,476 | $1,783,986 | $2,030,950 | +$246,964 | +13.84% | |
| Bnp Paribas Financial Markets | 0.00% | 158,950 | $1,745,271 | $1,986,875 | +$241,604 | +13.84% | |
| Goldman Sachs Group Inc | 0.00% | 155,929 | $1,712,100 | $1,949,113 | +$237,013 | +13.84% | |
| Two Sigma Investments, Lp | 0.00% | 121,004 | $1,328,624 | $1,512,550 | +$183,926 | +13.84% | |
| Hsbc Holdings Plc | 0.00% | 122,834 | $1,324,151 | $1,535,425 | +$211,274 | +15.96% | |
| Quadrature Capital Ltd | 0.01% | 118,129 | $1,297,056 | $1,476,613 | +$179,557 | +13.84% | |
| Squarepoint Ops Llc | 0.00% | 115,918 | $1,272,780 | $1,448,975 | +$176,195 | +13.84% | |
| Xtx Topco Ltd | 0.02% | 107,579 | $1,181,217 | $1,344,738 | +$163,521 | +13.84% | |
| M28 Capital Management Lp | 2.36% | 101,203 | $1,111,209 | $1,265,038 | +$153,829 | +13.84% | |
| Marshall Wace, Llp | 0.00% | 72,039 | $790,989 | $900,488 | +$109,499 | +13.84% | |
| Birchview Capital, Lp | 0.37% | 71,218 | $781,974 | $890,225 | +$108,251 | +13.84% | |
| Seven Fleet Capital Management Lp | 0.11% | 60,107 | $659,975 | $751,338 | +$91,363 | +13.84% | |
| Hrt Financial Lp | 0.00% | 30,748 | $337,000 | $384,350 | +$47,350 | +14.05% | |
| Geode Capital Management, Llc | 0.00% | 29,538 | $324,327 | $369,225 | +$44,898 | +13.84% | |
| Virtu Financial Llc | 0.01% | 25,641 | $282,000 | $320,513 | +$38,513 | +13.66% | |
| Bank Of America Corp | 0.00% | 25,280 | $277,574 | $316,000 | +$38,426 | +13.84% | |
| Trexquant Investment Lp | 0.00% | 23,842 | $261,785 | $298,025 | +$36,240 | +13.84% | |
| Verdad Advisers, Lp | 0.21% | 20,400 | $223,992 | $255,000 | +$31,008 | +13.84% | |
| Scientech Research Llc | 0.17% | 19,133 | $210,080 | $239,163 | +$29,083 | +13.84% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 16,930 | $185,891 | $211,625 | +$25,734 | +13.84% |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.05% | 16,334 | $179,347 | $204,175 | +$24,828 | +13.84% | |
| Persistent Asset Partners Ltd | 0.05% | 15,170 | $166,567 | $189,625 | +$23,058 | +13.84% |
Frequently asked questions about SLN
Who owns the most SLN stock?
The largest holders of SLN are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for SILENCE THERAPEUTICS PLC-ADR (SLN).
Is SLN widely held by superinvestors?
Many widely followed stocks like SLN appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly SLN is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.