SLN Institutional Ownership & Shareholders
SILENCE THERAPEUTICS PLC-ADR (SLN) is currently held by 73 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $239.00M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Siren, L.L.C. is currently the largest disclosed institutional shareholder of SLN tracked by InsiderSet, reporting ownership valued at approximately $36.36M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $65.43M, representing an estimated gain of +79.96% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 69% of the total disclosed SLN value among the investors covered in this analysis. Major shareholders include Siren, L.L.C., Tcg Crossover Management, Llc, Redmile Group, Llc, and several other long-term asset managers with concentrated positions in SILENCE THERAPEUTICS PLC-ADR (SLN).
This page ranks the largest institutional SLN shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
73
Total Reported Value
$239.00M
Largest Holder
Siren, L.L.C.
Largest Position
$36.36M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
86
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Siren, L.L.C. | 0.74% | 3,311,438 | $36,359,589 | $65,434,015 | +$29,074,426 | +79.96% | |
| Tcg Crossover Management, Llc | 0.80% | 3,033,560 | $33,308,489 | $59,943,146 | +$26,634,657 | +79.96% | |
| Redmile Group, Llc | 1.60% | 2,164,777 | $23,769,251 | $42,775,994 | +$19,006,743 | +79.96% | |
| Nantahala Capital Management, Llc | 0.89% | 1,346,731 | $14,787,106 | $26,611,405 | +$11,824,299 | +79.96% | |
| Citadel Advisors Llc | 0.01% | 1,329,625 | $14,599,282 | $26,273,390 | +$11,674,108 | +79.96% | |
| Nextech Invest, Ltd. | 0.50% | 952,400 | $10,457,352 | $18,819,424 | +$8,362,072 | +79.96% | |
| Millennium Management Llc | 0.01% | 909,279 | $9,983,883 | $17,967,353 | +$7,983,470 | +79.96% | |
| Tetragon Partners Gp Ltd | 1.37% | 764,256 | $8,391,531 | $15,101,699 | +$6,710,168 | +79.96% | |
| Soleus Capital Management, L.P. | 0.24% | 630,000 | $6,917,400 | $12,448,800 | +$5,531,400 | +79.96% | |
| Balyasny Asset Management L.P. | 0.01% | 610,980 | $6,708,560 | $12,072,965 | +$5,364,405 | +79.96% | |
| 5Am Venture Management, Llc | 1.82% | 476,200 | $5,228,676 | $9,409,712 | +$4,181,036 | +79.96% | |
| Great Point Partners Llc | 1.16% | 450,000 | $4,941,000 | $8,892,000 | +$3,951,000 | +79.96% | |
| Morgan Stanley | 0.00% | 403,172 | $4,426,828 | $7,966,679 | +$3,539,851 | +79.96% | |
| Ameriprise Financial Inc | 0.00% | 370,052 | $4,063,171 | $7,312,228 | +$3,249,057 | +79.96% | |
| Jane Street Group, Llc | 0.00% | 369,151 | $4,053,278 | $7,294,424 | +$3,241,146 | +79.96% | |
| Adar1 Capital Management, Llc | 0.17% | 338,373 | $3,715,336 | $6,686,250 | +$2,970,914 | +79.96% | |
| Summittx Capital, L.P. | 0.09% | 326,648 | $3,586,595 | $6,454,564 | +$2,867,969 | +79.96% | |
| Schonfeld Strategic Advisors Llc | 0.02% | 269,348 | $2,957,439 | $5,322,316 | +$2,364,877 | +79.96% | |
| Ubs Group Ag | 0.00% | 243,152 | $2,669,809 | $4,804,684 | +$2,134,875 | +79.96% | |
| Ishara Investments Lp | 1.79% | 55,350 | $2,434,847 | $1,093,716 | -$1,341,131 | -55.08% | |
| Blackrock, Inc. | 0.00% | 219,917 | $2,414,689 | $4,345,560 | +$1,930,871 | +79.96% | |
| Bank Of Montreal | 0.00% | 201,734 | $2,215,039 | $3,986,264 | +$1,771,225 | +79.96% | |
| Boothbay Fund Management, Llc | 0.04% | 198,347 | $2,177,850 | $3,919,337 | +$1,741,487 | +79.96% | |
| Propel Bio Management, Llc | 1.10% | 191,733 | $2,105,228 | $3,788,644 | +$1,683,416 | +79.96% | |
| Susquehanna International Group, Llp | 0.00% | 184,519 | $2,026,019 | $3,646,095 | +$1,620,076 | +79.96% | |
| Fred Alger Management, Llc | 0.01% | 177,000 | $1,943,460 | $3,497,520 | +$1,554,060 | +79.96% | |
| Ikarian Capital, Llc | 0.30% | 830,784 | $1,827,725 | $16,416,292 | +$14,588,567 | +798.18% | |
| Qube Research & Technologies Ltd | 0.00% | 163,945 | $1,800,116 | $3,239,553 | +$1,439,437 | +79.96% | |
| Caption Management, Llc | 0.06% | 162,476 | $1,783,986 | $3,210,526 | +$1,426,540 | +79.96% | |
| Bnp Paribas Financial Markets | 0.00% | 158,950 | $1,745,271 | $3,140,852 | +$1,395,581 | +79.96% | |
| Goldman Sachs Group Inc | 0.00% | 155,929 | $1,712,100 | $3,081,157 | +$1,369,057 | +79.96% | |
| Two Sigma Investments, Lp | 0.00% | 121,004 | $1,328,624 | $2,391,039 | +$1,062,415 | +79.96% | |
| Hsbc Holdings Plc | 0.00% | 122,834 | $1,324,151 | $2,427,200 | +$1,103,049 | +83.30% | |
| Quadrature Capital Ltd | 0.01% | 118,129 | $1,297,056 | $2,334,229 | +$1,037,173 | +79.96% | |
| Squarepoint Ops Llc | 0.00% | 115,918 | $1,272,780 | $2,290,540 | +$1,017,760 | +79.96% | |
| Xtx Topco Ltd | 0.02% | 107,579 | $1,181,217 | $2,125,761 | +$944,544 | +79.96% | |
| M28 Capital Management Lp | 2.36% | 101,203 | $1,111,209 | $1,999,771 | +$888,562 | +79.96% | |
| Marshall Wace, Llp | 0.00% | 72,039 | $790,989 | $1,423,491 | +$632,502 | +79.96% | |
| Birchview Capital, Lp | 0.37% | 71,218 | $781,974 | $1,407,268 | +$625,294 | +79.96% | |
| Seven Fleet Capital Management Lp | 0.11% | 60,107 | $659,975 | $1,187,714 | +$527,739 | +79.96% | |
| Y-Intercept (Hong Kong) Ltd | 0.01% | 40,107 | $438,370 | $792,514 | +$354,144 | +80.79% | |
| Hrt Financial Lp | 0.00% | 30,748 | $337,000 | $607,580 | +$270,580 | +80.29% | |
| Geode Capital Management, Llc | 0.00% | 29,538 | $324,327 | $583,671 | +$259,344 | +79.96% | |
| Virtu Financial Llc | 0.01% | 25,641 | $282,000 | $506,666 | +$224,666 | +79.67% | |
| Bank Of America Corp | 0.00% | 25,280 | $277,574 | $499,533 | +$221,959 | +79.96% | |
| Trexquant Investment Lp | 0.00% | 23,842 | $261,785 | $471,118 | +$209,333 | +79.96% | |
| Verdad Advisers, Lp | 0.21% | 20,400 | $223,992 | $403,104 | +$179,112 | +79.96% | |
| Scientech Research Llc | 0.17% | 19,133 | $210,080 | $378,068 | +$167,988 | +79.96% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 16,930 | $185,891 | $334,537 | +$148,646 | +79.96% |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.05% | 16,334 | $179,347 | $322,760 | +$143,413 | +79.96% |
Frequently asked questions about SLN
Who are the largest institutional holders of SLN?
The largest institutional holders of SLN reported in the latest SEC Form 13F filings include Siren, L.L.C., Tcg Crossover Management, Llc, Redmile Group, Llc, Nantahala Capital Management, Llc, and Citadel Advisors Llc. InsiderSet ranks institutional holders by their latest reported SLN position.
What is SLN institutional ownership?
This page tracks SLN positions reported by institutional investment managers through SEC Form 13F. SILENCE THERAPEUTICS PLC-ADR (SLN) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own SLN?
InsiderSet currently tracks 73 institutional managers reporting SLN holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of SLN shareholders.
How much SLN stock do institutions own?
Institutional investment managers disclosed approximately $239.00M in SLN holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was SLN institutional ownership last updated?
The latest SLN institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional SLN holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its SLN position after the reporting date.
Are institutions buying or selling SLN?
Institutional buying and selling can be analyzed by comparing SLN positions across consecutive 13F reporting periods. InsiderSet's SLN Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View SLN ownership changes.
How has SLN institutional ownership changed over time?
InsiderSet tracks SLN institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.