SILENCE THERAPEUTICS PLC-ADR (SLN) Top Institutional Shareholders
SILENCE THERAPEUTICS PLC-ADR (SLN) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $100.45M in SLN holdings during the latest filing period.
Tcg Crossover Management, Llc is currently the largest disclosed institutional shareholder of SLN tracked by InsiderSet, reporting ownership valued at approximately $15.99M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $20.51M, representing an estimated gain of +28.27% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 82% of the total disclosed SLN value among the investors covered in this analysis. Major shareholders include Tcg Crossover Management, Llc, Siren, L.L.C., Redmile Group, Llc, and several other long-term asset managers with concentrated positions in SILENCE THERAPEUTICS PLC-ADR (SLN).
This page ranks the largest institutional SLN shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
54
Total Reported Value
$100.45M
Largest Holder
Tcg Crossover Management, Llc
Largest Position
$15.99M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
63
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Tcg Crossover Management, Llc | 0.46% | 3,033,560 | $15,986,861 | $20,506,866 | +$4,520,005 | +28.27% | |
| Siren, L.L.C. | 0.43% | 2,911,438 | $15,343,278 | $19,681,321 | +$4,338,043 | +28.27% | |
| Redmile Group, Llc | 0.76% | 2,164,777 | $11,408,375 | $14,633,893 | +$3,225,518 | +28.27% | |
| Nantahala Capital Management, Llc | 0.71% | 2,146,731 | $11,313,272 | $14,511,902 | +$3,198,630 | +28.27% | |
| Citadel Advisors Llc | 0.00% | 1,234,807 | $6,507,433 | $8,347,295 | +$1,839,862 | +28.27% | |
| Millennium Management Llc | 0.00% | 1,074,191 | $5,660,987 | $7,261,531 | +$1,600,544 | +28.27% | |
| Great Point Partners Llc | 1.32% | 1,020,489 | $5,377,977 | $6,898,506 | +$1,520,529 | +28.27% | |
| Nextech Invest, Ltd. | 0.35% | 952,400 | $5,019,148 | $6,438,224 | +$1,419,076 | +28.27% | |
| Tetragon Partners Gp Ltd | 0.65% | 630,161 | $3,320,948 | $4,259,888 | +$938,940 | +28.27% | |
| 5Am Venture Management, Llc | 0.70% | 476,200 | $2,509,574 | $3,219,112 | +$709,538 | +28.27% | |
| Ikarian Capital, Llc | 0.25% | 865,784 | $1,731,568 | $5,852,700 | +$4,121,132 | +238.00% | |
| Jones Hill Capital Lp | 0.34% | 301,604 | $1,589,453 | $2,038,843 | +$449,390 | +28.27% | |
| Ubs Group Ag | 0.00% | 246,937 | $1,301,358 | $1,669,294 | +$367,936 | +28.27% | |
| Boothbay Fund Management, Llc | 0.03% | 209,088 | $1,101,894 | $1,413,435 | +$311,541 | +28.27% | |
| Blackrock, Inc. | 0.00% | 204,777 | $1,079,175 | $1,384,293 | +$305,118 | +28.27% | |
| Bank Of Montreal | 0.00% | 202,901 | $1,069,288 | $1,371,611 | +$302,323 | +28.27% | |
| Adar1 Capital Management, Llc | 0.05% | 172,157 | $907,267 | $1,163,781 | +$256,514 | +28.27% | |
| Marshall Wace, Llp | 0.00% | 169,616 | $893,877 | $1,146,604 | +$252,727 | +28.27% | |
| Seven Fleet Capital Management Lp | 0.26% | 156,759 | $826,120 | $1,059,691 | +$233,571 | +28.27% | |
| Bnp Paribas Financial Markets | 0.00% | 147,668 | $778,210 | $998,236 | +$220,026 | +28.27% | |
| Ishara Investments Lp | 0.75% | 140,500 | $740,435 | $949,780 | +$209,345 | +28.27% | |
| Hsbc Holdings Plc | 0.00% | 122,834 | $639,965 | $830,358 | +$190,393 | +29.75% | |
| Point72 Asset Management, L.P. | 0.00% | 119,711 | $630,877 | $809,246 | +$178,369 | +28.27% | |
| Susquehanna International Group, Llp | 0.00% | 115,281 | $607,531 | $779,300 | +$171,769 | +28.27% | |
| Xtx Topco Ltd | 0.01% | 106,002 | $558,631 | $716,574 | +$157,943 | +28.27% | |
| Qube Research & Technologies Ltd | 0.00% | 104,555 | $551,005 | $706,792 | +$155,787 | +28.27% | |
| M28 Capital Management Lp | 0.99% | 101,203 | $533,340 | $684,132 | +$150,792 | +28.27% | |
| Jane Street Group, Llc | 0.00% | 100,927 | $531,885 | $682,267 | +$150,382 | +28.27% | |
| Squarepoint Ops Llc | 0.00% | 89,469 | $471,502 | $604,810 | +$133,308 | +28.27% | |
| Morgan Stanley | 0.00% | 65,486 | $345,112 | $442,685 | +$97,573 | +28.27% | |
| Goldman Sachs Group Inc | 0.00% | 52,511 | $276,733 | $354,974 | +$78,241 | +28.27% | |
| Bank Of America Corp | 0.00% | 29,773 | $156,904 | $201,265 | +$44,361 | +28.27% | |
| Geode Capital Management, Llc | 0.00% | 29,538 | $155,665 | $199,677 | +$44,012 | +28.27% | |
| Raymond James Financial Inc | 0.00% | 25,000 | $131,750 | $169,000 | +$37,250 | +28.27% | |
| Two Sigma Investments, Lp | 0.00% | 16,203 | $85,390 | $109,532 | +$24,142 | +28.27% | |
| Rhumbline Advisers | 0.00% | 13,935 | $73,431 | $94,201 | +$20,770 | +28.28% | |
| Dynamic Technology Lab Private Ltd | 0.01% | 10,490 | $55,282 | $70,912 | +$15,630 | +28.27% | |
| Gamma Investing Llc | 0.00% | 9,365 | $49,354 | $63,307 | +$13,953 | +28.27% | |
| China Universal Asset Management Co., Ltd. | 0.00% | 8,335 | $43,925 | $56,345 | +$12,420 | +28.27% | |
| Barclays Plc | 0.00% | 2,937 | $15,478 | $19,854 | +$4,376 | +28.27% | |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | 2,450 | $12,912 | $16,562 | +$3,650 | +28.27% | |
| Jones Financial Companies Lllp | 0.00% | 2,500 | $12,325 | $16,900 | +$4,575 | +37.12% | |
| Tower Research Capital Llc (Trc) | 0.00% | 2,313 | $12,190 | $15,636 | +$3,446 | +28.27% | |
| Citigroup Inc | 0.00% | 1,835 | $9,670 | $12,405 | +$2,735 | +28.28% | |
| Parallel Advisors, Llc | 0.00% | 1,300 | $6,851 | $8,788 | +$1,937 | +28.27% | |
| Gf Fund Management Co. Ltd. | 0.00% | 1,047 | $5,518 | $7,078 | +$1,560 | +28.27% | |
| Simplex Trading, Llc | 0.00% | 612 | $3,225 | $4,137 | +$912 | +28.28% | |
| Sg Americas Securities, Llc | 0.00% | 286,698 | $1,511 | $1,938,078 | +$1,936,567 | +128164.62% | |
| Steward Partners Investment Advisory, Llc | 0.00% | 100 | $527 | $676 | +$149 | +28.27% | |
| Rockefeller Capital Management L.P. | 0.00% | 45 | $237 | $304 | +$67 | +28.35% |
Frequently asked questions about SLN
Who owns the most SLN stock?
The largest holders of SLN are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for SILENCE THERAPEUTICS PLC-ADR (SLN).
Is SLN widely held by superinvestors?
Many widely followed stocks like SLN appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly SLN is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.