MADRIGAL PHARMACEUTICALS INC (MDGL) Institutional Shareholders
MADRIGAL PHARMACEUTICALS INC (MDGL) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $12.42B in MDGL holdings during the latest filing period.
Baker Bros. Advisors Lp is currently the largest disclosed institutional shareholder of MDGL tracked by InsiderSet, reporting ownership valued at approximately $1.15B in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $1.09B, representing an estimated loss of -5.47% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 58% of the total disclosed MDGL value among the investors covered in this analysis. Major shareholders include Baker Bros. Advisors Lp, Rtw Investments, Lp, Janus Henderson Group Plc, and several other long-term asset managers with concentrated positions in MADRIGAL PHARMACEUTICALS INC (MDGL).
This page ranks the largest institutional MDGL shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
403
Total Reported Value
$12.42B
Largest Holder
Baker Bros. Advisors Lp
Largest Position
$1.15B
Insider Transactions (90d)
29
Latest Filing Quarter
Q2 2026
New Institutional Positions
56
Funds Exiting Positions
1
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Baker Bros. Advisors Lp | 5.77% | 2,143,131 | $1,150,754,190 | $1,087,767,570 | -$62,986,620 | -5.47% | |
| Rtw Investments, Lp | 9.14% | 1,993,687 | $1,070,510,235 | $1,011,915,774 | -$58,594,461 | -5.47% | |
| Janus Henderson Group Plc | 0.52% | 2,018,647 | $1,051,727,476 | $1,024,584,471 | -$27,143,005 | -2.58% | |
| Avoro Capital Advisors Llc | 8.84% | 1,833,333 | $984,408,154 | $930,526,497 | -$53,881,657 | -5.47% | |
| Paulson & Co. Inc. | 27.94% | 1,340,020 | $719,523,739 | $680,140,551 | -$39,383,188 | -5.47% | |
| Blackrock, Inc. | 0.01% | 1,200,770 | $644,753,455 | $609,462,821 | -$35,290,634 | -5.47% | |
| Vanguard Capital Management Llc | 0.01% | 835,668 | $448,711,933 | $424,151,650 | -$24,560,283 | -5.47% | |
| Wellington Management Group Llp | 0.08% | 825,714 | $443,367,132 | $419,099,398 | -$24,267,734 | -5.47% | |
| Vanguard Portfolio Management Llc | 0.02% | 781,731 | $419,750,461 | $396,775,386 | -$22,975,075 | -5.47% | |
| State Street Corp | 0.01% | 527,057 | $282,995,975 | $267,513,051 | -$15,482,924 | -5.47% | |
| Citadel Advisors Llc | 0.16% | 507,233 | $272,358,759 | $257,451,181 | -$14,907,578 | -5.47% | |
| Ubs Group Ag | 0.03% | 401,708 | $215,697,110 | $203,890,912 | -$11,806,198 | -5.47% | |
| Geode Capital Management, Llc | 0.01% | 374,880 | $201,342,418 | $190,274,093 | -$11,068,325 | -5.50% | |
| Fmr Llc | 0.01% | 356,201 | $191,262,164 | $180,793,380 | -$10,468,784 | -5.47% | |
| William Blair Investment Management, Llc | 0.52% | 324,123 | $174,037,845 | $164,511,870 | -$9,525,975 | -5.47% | |
| Invesco Ltd. | 0.01% | 301,435 | $161,855,524 | $152,996,349 | -$8,859,175 | -5.47% | |
| Armistice Capital, Llc | 4.28% | 288,000 | $154,641,600 | $146,177,280 | -$8,464,320 | -5.47% | |
| Goldman Sachs Group Inc | 0.01% | 246,280 | $132,240,046 | $125,001,877 | -$7,238,169 | -5.47% | |
| Polar Capital Holdings Plc | 0.37% | 244,274 | $131,162,924 | $123,983,711 | -$7,179,213 | -5.47% | |
| Ameriprise Financial Inc | 0.03% | 231,205 | $124,147,079 | $117,350,410 | -$6,796,669 | -5.47% | |
| Norges Bank | 0.01% | 213,886 | $114,846,088 | $108,559,978 | -$6,286,110 | -5.47% | |
| Artisan Partners Limited Partnership | 0.18% | 210,205 | $112,869,575 | $106,691,650 | -$6,177,925 | -5.47% | |
| Pictet Asset Management Holding Sa | 0.10% | 192,896 | $103,486,147 | $97,906,294 | -$5,579,853 | -5.39% | |
| Jane Street Group, Llc | 0.07% | 191,541 | $102,847,940 | $97,218,550 | -$5,629,390 | -5.47% | |
| Alliancebernstein L.P. | 0.03% | 189,458 | $99,175,579 | $96,161,302 | -$3,014,277 | -3.04% | |
| Charles Schwab Investment Management Inc | 0.01% | 184,324 | $98,972,771 | $93,555,489 | -$5,417,282 | -5.47% | |
| Sixth Street Partners Management Company, L.P. | 0.01% | 184,324 | $98,972,771 | $93,555,489 | -$5,417,282 | -5.47% | |
| Toronto Dominion Bank | 0.16% | 181,432 | $97,419,912 | $92,087,626 | -$5,332,286 | -5.47% | |
| Rock Springs Capital Management Lp | 4.59% | 174,999 | $93,965,713 | $88,822,492 | -$5,143,221 | -5.47% | |
| Hood River Capital Management Llc | 0.66% | 169,084 | $90,789,654 | $85,820,275 | -$4,969,379 | -5.47% | |
| Holocene Advisors, Lp | 0.19% | 152,924 | $82,112,542 | $77,618,105 | -$4,494,437 | -5.47% | |
| Susquehanna International Group, Llp | 0.07% | 148,610 | $79,796,140 | $75,428,492 | -$4,367,648 | -5.47% | |
| Morgan Stanley | 0.00% | 139,009 | $74,641,318 | $70,555,408 | -$4,085,910 | -5.47% | |
| Point72 Asset Management, L.P. | 0.11% | 137,029 | $73,577,722 | $69,550,439 | -$4,027,283 | -5.47% | |
| Bank Of America Corp | 0.00% | 134,036 | $71,970,631 | $68,031,312 | -$3,939,319 | -5.47% | |
| Bank Of New York Mellon Corp | 0.01% | 128,520 | $69,008,635 | $65,231,611 | -$3,777,024 | -5.47% | |
| Woodline Partners Lp | 0.21% | 125,899 | $67,601,468 | $63,901,296 | -$3,700,172 | -5.47% | |
| Assenagon Asset Management S.A. | 0.09% | 124,214 | $66,696,707 | $63,046,058 | -$3,650,649 | -5.47% | |
| Vanguard Fiduciary Trust Co | 0.01% | 121,583 | $65,283,992 | $61,710,667 | -$3,573,325 | -5.47% | |
| Clearbridge Investments, Llc | 0.05% | 109,325 | $58,701,796 | $55,488,997 | -$3,212,799 | -5.47% | |
| Erste Asset Management Gmbh | 0.45% | 110,210 | $58,111,529 | $55,938,188 | -$2,173,341 | -3.74% | |
| Marshall Wace, Llp | 0.05% | 101,859 | $54,693,192 | $51,699,554 | -$2,993,638 | -5.47% | |
| Fiera Capital Corp | 0.19% | 99,857 | $53,618,216 | $50,683,419 | -$2,934,797 | -5.47% | |
| American Century Companies Inc | 0.02% | 99,396 | $53,371,576 | $50,449,434 | -$2,922,142 | -5.48% | |
| Northern Trust Corp | 0.01% | 98,510 | $52,894,944 | $49,999,736 | -$2,895,208 | -5.47% | |
| New York State Common Retirement Fund | 0.06% | 94,743 | $50,872,254 | $48,087,757 | -$2,784,497 | -5.47% | |
| Westfield Capital Management Co Lp | 0.16% | 93,931 | $50,436,250 | $47,675,618 | -$2,760,632 | -5.47% | |
| Deutsche Bank Ag\ | 0.01% | 83,916 | $45,058,696 | $42,592,405 | -$2,466,291 | -5.47% | |
| Millennium Management Llc | 0.03% | 81,196 | $43,598,192 | $41,211,842 | -$2,386,350 | -5.47% | |
| Alkeon Capital Management Llc | 0.17% | 80,000 | $42,956,000 | $40,604,800 | -$2,351,200 | -5.47% |
Frequently asked questions about MDGL
Who owns the most MDGL stock?
The largest holders of MDGL are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for MADRIGAL PHARMACEUTICALS INC (MDGL).
Is MDGL widely held by superinvestors?
Many widely followed stocks like MDGL appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly MDGL is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.