ZYMEWORKS INC (ZYME) Institutional Shareholders
ZYMEWORKS INC (ZYME) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $1.79B in ZYME holdings during the latest filing period.
Ecor1 Capital, Llc is currently the largest disclosed institutional shareholder of ZYME tracked by InsiderSet, reporting ownership valued at approximately $600.45M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $577.02M, representing an estimated loss of -3.90% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 73% of the total disclosed ZYME value among the investors covered in this analysis. Major shareholders include Ecor1 Capital, Llc, Rubric Capital Management Lp, Blackrock, Inc., and several other long-term asset managers with concentrated positions in ZYMEWORKS INC (ZYME).
This page ranks the largest institutional ZYME shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
202
Total Reported Value
$1.79B
Largest Holder
Ecor1 Capital, Llc
Largest Position
$600.45M
Insider Transactions (90d)
1
Latest Filing Quarter
Q2 2026
New Institutional Positions
52
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Ecor1 Capital, Llc | 29.77% | 22,970,388 | $600,445,942 | $577,016,147 | -$23,429,795 | -3.90% | |
| Rubric Capital Management Lp | 1.68% | 7,000,000 | $182,980,000 | $175,840,000 | -$7,140,000 | -3.90% | |
| Blackrock, Inc. | 0.00% | 4,251,030 | $111,121,925 | $106,785,874 | -$4,336,051 | -3.90% | |
| Perceptive Advisors Llc | 1.70% | 4,182,953 | $109,342,391 | $105,075,779 | -$4,266,612 | -3.90% | |
| Bvf Inc/Il | 2.44% | 3,649,142 | $95,388,572 | $91,666,447 | -$3,722,125 | -3.90% | |
| Morgan Stanley | 0.00% | 2,231,260 | $58,325,141 | $56,049,251 | -$2,275,890 | -3.90% | |
| Bnp Paribas Asset Management Holding S.A. | 0.05% | 1,781,116 | $46,558,373 | $44,741,634 | -$1,816,739 | -3.90% | |
| Vanguard Capital Management Llc | 0.00% | 1,558,998 | $40,752,208 | $39,162,030 | -$1,590,178 | -3.90% | |
| Assenagon Asset Management S.A. | 0.04% | 1,252,027 | $32,727,986 | $31,450,918 | -$1,277,068 | -3.90% | |
| Nextech Invest, Ltd. | 1.38% | 1,113,946 | $29,118,548 | $27,982,324 | -$1,136,224 | -3.90% | |
| State Street Corp | 0.00% | 1,088,216 | $28,445,966 | $27,335,986 | -$1,109,980 | -3.90% | |
| Dimensional Fund Advisors Lp | 0.00% | 994,955 | $25,995,770 | $24,993,270 | -$1,002,500 | -3.86% | |
| Citadel Advisors Llc | 0.01% | 914,136 | $23,895,516 | $22,963,096 | -$932,420 | -3.90% | |
| Nomura Asset Management International Inc. | 0.03% | 889,802 | $23,259,000 | $22,351,826 | -$907,174 | -3.90% | |
| Fmr Llc | 0.00% | 702,568 | $18,365,133 | $17,648,508 | -$716,625 | -3.90% | |
| Geode Capital Management, Llc | 0.00% | 692,410 | $18,099,012 | $17,393,339 | -$705,673 | -3.90% | |
| Prosight Management, Lp | 3.04% | 674,434 | $17,629,705 | $16,941,782 | -$687,923 | -3.90% | |
| Qube Research & Technologies Ltd | 0.02% | 593,590 | $15,516,443 | $14,910,981 | -$605,462 | -3.90% | |
| Vanguard Portfolio Management Llc | 0.00% | 510,032 | $13,332,236 | $12,812,004 | -$520,232 | -3.90% | |
| Redmile Group, Llc | 0.86% | 491,654 | $12,851,836 | $12,350,348 | -$501,488 | -3.90% | |
| Capricorn Fund Managers Ltd | 1.02% | 486,529 | $12,717,868 | $12,221,608 | -$496,260 | -3.90% | |
| Goldman Sachs Group Inc | 0.00% | 470,822 | $12,307,288 | $11,827,049 | -$480,239 | -3.90% | |
| Arrowstreet Capital, Limited Partnership | 0.00% | 418,497 | $10,939,512 | $10,512,645 | -$426,867 | -3.90% | |
| Deutsche Bank Ag\ | 0.00% | 397,190 | $10,382,547 | $9,977,413 | -$405,134 | -3.90% | |
| Hillsdale Investment Management Inc. | 0.23% | 382,922 | $10,009,581 | $9,619,001 | -$390,580 | -3.90% | |
| First Trust Advisors Lp | 0.01% | 340,363 | $8,897,088 | $8,549,919 | -$347,169 | -3.90% | |
| Granahan Investment Management, Llc | 0.31% | 336,157 | $8,787,144 | $8,444,264 | -$342,880 | -3.90% | |
| Northern Trust Corp | 0.00% | 321,073 | $8,392,849 | $8,065,354 | -$327,495 | -3.90% | |
| Ubs Am, A Distinct Business Unit Of Ubs Asset Management Americas Llc | 0.00% | 319,385 | $7,997,401 | $8,022,951 | +$25,550 | +0.32% | |
| Pictet Asset Management Holding Sa | 0.01% | 308,187 | $7,446,189 | $7,741,657 | +$295,468 | +3.97% | |
| Picton Mahoney Asset Management | 0.07% | 271,343 | $7,092,908 | $6,816,136 | -$276,772 | -3.90% | |
| Silvercrest Asset Management Group Llc | 0.04% | 223,766 | $5,849,243 | $5,621,002 | -$228,241 | -3.90% | |
| Bank Of America Corp | 0.00% | 219,071 | $5,726,515 | $5,503,064 | -$223,451 | -3.90% | |
| Wells Fargo & Company/Mn | 0.00% | 217,199 | $5,677,573 | $5,456,039 | -$221,534 | -3.90% | |
| Summittx Capital, L.P. | 0.15% | 210,802 | $5,510,364 | $5,295,346 | -$215,018 | -3.90% | |
| Man Group Plc | 0.01% | 210,779 | $5,509,763 | $5,294,768 | -$214,995 | -3.90% | |
| Federated Hermes, Inc. | 0.01% | 187,995 | $4,914,190 | $4,722,434 | -$191,756 | -3.90% | |
| Raymond James Financial Inc | 0.00% | 166,416 | $4,350,114 | $4,180,370 | -$169,744 | -3.90% | |
| State Of Wisconsin Investment Board | 0.01% | 155,579 | $4,066,835 | $3,908,144 | -$158,691 | -3.90% | |
| Charles Schwab Investment Management Inc | 0.00% | 152,416 | $3,984,154 | $3,828,690 | -$155,464 | -3.90% | |
| Sixth Street Partners Management Company, L.P. | 0.00% | 152,416 | $3,984,154 | $3,828,690 | -$155,464 | -3.90% | |
| Kennedy Capital Management Llc | 0.07% | 145,386 | $3,800,390 | $3,652,096 | -$148,294 | -3.90% | |
| D. E. Shaw & Co., Inc. | 0.00% | 144,807 | $3,785,255 | $3,637,552 | -$147,703 | -3.90% | |
| Diadema Partners Lp | 1.31% | 142,132 | $3,715,330 | $3,570,356 | -$144,974 | -3.90% | |
| Citigroup Inc | 0.00% | 131,441 | $3,435,868 | $3,301,798 | -$134,070 | -3.90% | |
| Bank Of New York Mellon Corp | 0.00% | 131,106 | $3,427,107 | $3,293,383 | -$133,724 | -3.90% | |
| Xtx Topco Ltd | 0.04% | 125,877 | $3,290,425 | $3,162,030 | -$128,395 | -3.90% | |
| Nuveen, Llc | 0.00% | 119,389 | $3,120,829 | $2,999,052 | -$121,777 | -3.90% | |
| Panagora Asset Management Inc | 0.01% | 118,603 | $3,100,282 | $2,979,307 | -$120,975 | -3.90% | |
| Ubs Group Ag | 0.00% | 115,095 | $3,008,583 | $2,891,186 | -$117,397 | -3.90% |
Frequently asked questions about ZYME
Who owns the most ZYME stock?
The largest holders of ZYME are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ZYMEWORKS INC (ZYME).
Is ZYME widely held by superinvestors?
Many widely followed stocks like ZYME appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ZYME is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.