AMYLYX PHARMACEUTICALS INC (AMLX) Institutional Ownership Changes & 13F Activity

AMYLYX PHARMACEUTICALS INC (AMLX). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Adage Capital Partners Gp, L.L.C., Almitas Capital Llc, Alyeska Investment Group, L.P., Great Point Partners Llc, and Barclays Plc.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Manufacturers Life Insurance Company, TheSell-953-2.5%37,828$679.39KQ2 2026Sep 09, 2026
Citadel Advisors LlcSell-232,846-56.6%178,686$3.21MQ2 2026Sep 02, 2026
Corient Private Wealth LlcBuy+59,32259,322$1.07MQ2 2026Aug 27, 2026
Optimize Financial IncSell-111-0.3%31,890$572.74KQ2 2026Aug 27, 2026
California State Teachers Retirement SystemBuy+14,870+22.9%79,872$1.43MQ2 2026Aug 24, 2026
Nantahala Capital Management, LlcSell-49,000-9.1%486,684$8.74MQ2 2026Aug 19, 2026
Fulcrum Asset Management LlpBuy+4,4004,400$82.28KQ2 2026Aug 18, 2026
Almitas Capital LlcSell-1,147,716-54.1%974,881$17.51MQ2 2026Aug 17, 2026
Seven Fleet Capital Management LpSell-2,131-12.8%14,540$261.14KQ2 2026Aug 17, 2026
Strive Financial Group ,LlcBuy+650650$11.67KQ2 2026Aug 17, 2026
Adage Capital Partners Gp, L.L.C.Sell-1,660,764-46.6%1,900,000$34.12MQ2 2026Aug 14, 2026
Alyeska Investment Group, L.P.Buy+1,053,0151,053,015$18.91MQ2 2026Aug 14, 2026
Great Point Partners LlcSell-1,050,000-60.0%700,000$12.57MQ2 2026Aug 14, 2026
Barclays PlcSell-915,596-94.2%56,258$1.01MQ2 2026Aug 14, 2026
Bank Of America CorpSell-508,848-38.2%821,841$14.76MQ2 2026Aug 14, 2026
Adar1 Capital Management, LlcSell-506,226-50.6%494,378$8.88MQ2 2026Aug 14, 2026
Two Sigma Investments, LpBuy+431,490+266.4%593,435$10.66MQ2 2026Aug 14, 2026
Nearwater Capital Markets, LtdBuy+425,000425,000$7.63MQ2 2026Aug 14, 2026
Balyasny Asset Management L.P.Sell-422,297-38.1%684,974$12.30MQ2 2026Aug 14, 2026
Logos Global Management LpSell-350,000-50.0%350,000$6.29MQ2 2026Aug 14, 2026
Trexquant Investment LpBuy+349,439349,439$6.28MQ2 2026Aug 14, 2026
Ensign Peak Advisors, IncBuy+305,441305,441$5.49MQ2 2026Aug 14, 2026
Jane Street Group, LlcBuy+299,565299,565$5.38MQ2 2026Aug 14, 2026
Stempoint Capital LpSell-285,381-42.6%384,304$6.90MQ2 2026Aug 14, 2026
Saturn V Capital Management LpBuy+274,216+6.3%4,624,101$83.05MQ2 2026Aug 14, 2026
683 Capital Management, LlcSell-250,488-16.4%1,279,512$22.98MQ2 2026Aug 14, 2026
Goldman Sachs Group IncBuy+232,248+8.8%2,858,239$51.33MQ2 2026Aug 14, 2026
Parkman Healthcare Partners LlcSell-222,676-35.8%398,782$7.16MQ2 2026Aug 14, 2026
Eventide Asset Management, LlcSell-186,422-12.3%1,327,536$23.84MQ2 2026Aug 14, 2026
Orbimed Advisors LlcBuy+183,400183,400$3.29MQ2 2026Aug 14, 2026
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Frequently asked questions about AMLX activity

  • Which institutional owners are buying AMLX?

    Institutional owners buying AMLX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in AMLX activity?

    "Buy" means an investor increased their reported position in AMLX compared to the prior reporting period. This reflects growing exposure to AMYLYX PHARMACEUTICALS INC (AMLX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in AMLX increasing?

    Institutional interest in AMLX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.