Definium Therapeutics, Inc. (DFTX) Institutional Ownership Changes & 13F Activity
Definium Therapeutics, Inc. (DFTX). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Price T Rowe Associates Inc, Avoro Capital Advisors Llc, Alliancebernstein L.P., Wellington Management Group Llp, and Ra Capital Management, L.P..
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Manufacturers Life Insurance Company, The | Buy | +119,964 | +454.3% | 146,368 | $6.89M | Q2 2026 | Sep 09, 2026 |
| Citadel Advisors Llc | Buy | +355,145 | +26.6% | 1,688,587 | $79.43M | Q2 2026 | Sep 02, 2026 |
| Allianz Asset Management Gmbh | Buy | +13,800 | — | 13,800 | $649.15K | Q2 2026 | Sep 02, 2026 |
| Corient Private Wealth Llc | Buy | +24,391 | — | 24,391 | $1.15M | Q2 2026 | Aug 27, 2026 |
| California State Teachers Retirement System | Buy | +128,346 | — | 128,346 | $6.04M | Q2 2026 | Aug 24, 2026 |
| Mercer Global Advisors Inc | Buy | +10,278 | — | 10,278 | $483.48K | Q2 2026 | Aug 19, 2026 |
| 49 Wealth Management, Llc | Buy | +5,772 | — | 5,772 | $271.51K | Q2 2026 | Aug 18, 2026 |
| Seven Fleet Capital Management Lp | Buy | +48,760 | +48.8% | 148,647 | $6.99M | Q2 2026 | Aug 17, 2026 |
| Price T Rowe Associates Inc | Buy | +4,582,031 | +6545.7% | 4,652,032 | $218.83M | Q2 2026 | Aug 14, 2026 |
| Avoro Capital Advisors Llc | Buy | +2,188,888 | +43.8% | 7,188,888 | $338.17M | Q2 2026 | Aug 14, 2026 |
| Alliancebernstein L.P. | Buy | +1,711,584 | +1866.4% | 1,803,287 | $34.08M | Q2 2026 | Aug 14, 2026 |
| Wellington Management Group Llp | Buy | +1,644,985 | +126.1% | 2,949,734 | $138.76M | Q2 2026 | Aug 14, 2026 |
| Ra Capital Management, L.P. | Buy | +1,500,000 | — | 1,500,000 | $70.56M | Q2 2026 | Aug 14, 2026 |
| Ameriprise Financial Inc | Buy | +1,148,363 | — | 1,148,363 | $54.02M | Q2 2026 | Aug 14, 2026 |
| Driehaus Capital Management Llc | Buy | +933,387 | +15.8% | 6,845,276 | $322.00M | Q2 2026 | Aug 14, 2026 |
| Polar Capital Holdings Plc | Buy | +777,253 | — | 777,253 | $36.56M | Q2 2026 | Aug 14, 2026 |
| Millennium Management Llc | Sell | -580,820 | -68.6% | 266,076 | $12.52M | Q2 2026 | Aug 14, 2026 |
| Blackstone Inc. | Buy | +561,612 | — | 561,612 | $26.42M | Q2 2026 | Aug 14, 2026 |
| Bamco Inc | Buy | +520,108 | — | 520,108 | $24.47M | Q2 2026 | Aug 14, 2026 |
| Octagon Capital Advisors Lp | Buy | +510,000 | +20.9% | 2,950,000 | $138.77M | Q2 2026 | Aug 14, 2026 |
| Catalio Capital Management, Lp | Sell | -475,312 | -45.8% | 562,672 | $26.47M | Q2 2026 | Aug 14, 2026 |
| Orbimed Advisors Llc | Sell | -438,600 | -54.6% | 365,400 | $17.19M | Q2 2026 | Aug 14, 2026 |
| Great Point Partners Llc | Buy | +425,000 | — | 425,000 | $19.99M | Q2 2026 | Aug 14, 2026 |
| Boxer Capital Management, Llc | Buy | +400,000 | +66.8% | 998,500 | $46.97M | Q2 2026 | Aug 14, 2026 |
| Cormorant Asset Management, Lp | Buy | +400,000 | — | 400,000 | $18.82M | Q2 2026 | Aug 14, 2026 |
| Balyasny Asset Management L.P. | Sell | -376,563 | -29.6% | 897,658 | $42.23M | Q2 2026 | Aug 14, 2026 |
| Duquesne Family Office Llc | Buy | +356,600 | — | 356,600 | $16.77M | Q2 2026 | Aug 14, 2026 |
| Point72 Asset Management, L.P. | Buy | +308,490 | +175.8% | 483,980 | $22.77M | Q2 2026 | Aug 14, 2026 |
| Holocene Advisors, Lp | Sell | -295,393 | -27.1% | 796,574 | $37.47M | Q2 2026 | Aug 14, 2026 |
| Awm Investment Company, Inc. | Sell | -292,093 | -27.1% | 784,800 | $36.92M | Q2 2026 | Aug 14, 2026 |
Frequently asked questions about DFTX activity
Which institutional owners are buying DFTX?
Institutional owners buying DFTX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in DFTX activity?
"Buy" means an investor increased their reported position in DFTX compared to the prior reporting period. This reflects growing exposure to Definium Therapeutics, Inc. (DFTX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in DFTX increasing?
Institutional interest in DFTX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.