PUMA BIOTECHNOLOGY INC (PBYI) Stock Institutional Trading Activity


PUMA BIOTECHNOLOGY INC (PBYI) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC, Causeway Capital Management, and Engaged Capital. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

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Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q4 2025Causeway Capital ManagementSell-78513,310$79,195
Q4 2025Renaissance Technologies LLCSell-27,4002,123,813$12,636,687
Q3 2025Renaissance Technologies LLCBuy276,5002,151,213$11,422,941
Q2 2025Renaissance Technologies LLCBuy45,5001,874,713$6,430,266
Q1 2025Causeway Capital ManagementBuy14,09514,095$41,721
Q1 2025Renaissance Technologies LLCBuy73,7001,829,213$5,414,470
Q4 2024Renaissance Technologies LLCSell-16,9001,755,513$5,354,315
Q3 2024Renaissance Technologies LLCBuy19,4001,772,413$4,519,653
Q2 2024Renaissance Technologies LLCBuy23,6001,753,013$5,714,822
Q1 2024Renaissance Technologies LLCBuy56,2001,729,413$9,166
Q4 2023Renaissance Technologies LLCSell-53,3891,673,213$7,245
Q3 2023Renaissance Technologies LLCSell-31,4111,726,602$4,541
Q2 2023Renaissance Technologies LLCSell-76,9001,758,013$6,206
Q1 2023Renaissance Technologies LLCBuy136,0701,834,913$5,670
Q4 2022Renaissance Technologies LLCSell-100,8191,698,843$7,186
Q3 2022Renaissance Technologies LLCSell-177,2731,799,662$4,265
Q2 2022Renaissance Technologies LLCBuy205,7001,976,935$5,634
Q1 2022Renaissance Technologies LLCSell-49,6231,771,235$5,101
Q4 2021Renaissance Technologies LLCBuy188,9231,820,858$5,535
Q3 2021Renaissance Technologies LLCBuy33,6001,631,935$11,440
Q2 2021Renaissance Technologies LLCBuy6,1001,598,335$14,673
Q1 2021Renaissance Technologies LLCSell-69,2001,592,235$15,477
Q4 2020Renaissance Technologies LLCBuy109,7381,661,435$17,046
Q3 2020Renaissance Technologies LLCBuy86,0001,551,697$15,657
Q2 2020Renaissance Technologies LLCBuy377,1001,465,697$15,287
Q1 2020Renaissance Technologies LLCBuy991,0971,088,597$9,188
Q4 2019Renaissance Technologies LLCSell-154,70097,500$853
Q2 2019Renaissance Technologies LLCBuy160,300252,200$3,205
Q1 2019Renaissance Technologies LLCSell-185,70091,900$3,565
Q4 2018Renaissance Technologies LLCBuy143,000277,600$5,649

Frequently asked questions about PBYI activity

  • Which institutional owners are buying PBYI?

    Institutional owners buying PBYI include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in PBYI activity?

    "Buy" means an investor increased their reported position in PBYI compared to the prior reporting period. This reflects growing exposure to PUMA BIOTECHNOLOGY INC (PBYI) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in PBYI increasing?

    Institutional interest in PBYI can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.