PUMA BIOTECHNOLOGY INC (PBYI) Institutional Selling Activity
Several institutional investors tracked by InsiderSet reduced exposure to PUMA BIOTECHNOLOGY INC (PBYI) during the quarter ended March 31, 2026 based on sequential SEC Form 13F filings.
The largest disclosed institutional seller of PBYI during the latest reporting period reduced its reported position by approximately $1.16M based on quarter-end filing values.
Institutional selling activity may reflect profit-taking, sector rotation, portfolio rebalancing, or changing conviction levels among major investment firms. InsiderSet tracks quarter-over-quarter holding reductions, full exits, estimated value changes, and historical selling activity using publicly disclosed SEC filing data.
The investors covered on this page collectively reduced approximately $1.16M in reported PBYI exposure during the latest filing period, although many institutional holders continue to maintain significant long-term ownership positions in PUMA BIOTECHNOLOGY INC.
| Portfolio quarter | Name | Type | Quantity | Remaining | Reported stock balance |
|---|---|---|---|---|---|
| Q1 2026 | Renaissance Technologies LLC | Sell | -181,400 | 1,942,413 | $12,412,019 |
Frequently asked questions about PBYI activity
Which institutional owners are buying PBYI?
Institutional owners buying PBYI include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in PBYI activity?
"Buy" means an investor increased their reported position in PBYI compared to the prior reporting period. This reflects growing exposure to PUMA BIOTECHNOLOGY INC (PBYI) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in PBYI increasing?
Institutional interest in PBYI can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.