Seaport Therapeutics, Inc. (SPTX) Institutional Ownership Changes & 13F Activity
Seaport Therapeutics, Inc. (SPTX). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Arch Venture Management, Llc, General Atlantic, L.P., Sofinnova Investments, Inc., Goldman Sachs Group Inc, and Canada Pension Plan Investment Board.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Manufacturers Life Insurance Company, The | Buy | +82,565 | — | 82,565 | $1.79M | Q2 2026 | Sep 09, 2026 |
| Citadel Advisors Llc | Buy | +191,144 | — | 191,144 | $4.15M | Q2 2026 | Sep 02, 2026 |
| Arch Venture Management, Llc | Buy | +6,294,951 | — | 6,294,951 | $136.60M | Q2 2026 | Aug 14, 2026 |
| General Atlantic, L.P. | Buy | +6,101,582 | — | 6,101,582 | $132.53M | Q2 2026 | Aug 14, 2026 |
| Sofinnova Investments, Inc. | Buy | +3,564,871 | — | 3,564,871 | $77.43M | Q2 2026 | Aug 14, 2026 |
| Goldman Sachs Group Inc | Buy | +2,178,642 | — | 2,178,642 | $47.32M | Q2 2026 | Aug 14, 2026 |
| Canada Pension Plan Investment Board | Buy | +1,975,791 | — | 1,975,791 | $42.91M | Q2 2026 | Aug 14, 2026 |
| Foresite Capital Management Vi Llc | Buy | +1,779,521 | — | 1,779,521 | $38.65M | Q2 2026 | Aug 14, 2026 |
| Price T Rowe Associates Inc | Buy | +1,308,604 | — | 1,308,604 | $28.42M | Q2 2026 | Aug 14, 2026 |
| Bellevue Group Ag | Buy | +1,100,000 | — | 1,100,000 | $23.89M | Q2 2026 | Aug 14, 2026 |
| Ra Capital Management, L.P. | Buy | +700,000 | — | 700,000 | $15.20M | Q2 2026 | Aug 14, 2026 |
| Woodline Partners Lp | Buy | +586,345 | — | 586,345 | $12.74M | Q2 2026 | Aug 14, 2026 |
| Braidwell Lp | Buy | +500,000 | — | 500,000 | $10.86M | Q2 2026 | Aug 14, 2026 |
| Perceptive Advisors Llc | Buy | +500,000 | — | 500,000 | $10.86M | Q2 2026 | Aug 14, 2026 |
| Seven Grand Managers, Llc | Buy | +225,000 | — | 225,000 | $4.89M | Q2 2026 | Aug 14, 2026 |
| Ameriprise Financial Inc | Buy | +131,788 | — | 131,788 | $2.86M | Q2 2026 | Aug 14, 2026 |
| Charles Schwab Investment Management Inc | Buy | +97,693 | — | 97,693 | $2.12M | Q2 2026 | Aug 14, 2026 |
| Pentwater Capital Management Lp | Buy | +83,000 | — | 83,000 | $1.80M | Q2 2026 | Aug 14, 2026 |
| Alyeska Investment Group, L.P. | Buy | +75,000 | — | 75,000 | $1.63M | Q2 2026 | Aug 14, 2026 |
| Millennium Management Llc | Buy | +45,337 | — | 45,337 | $984.72K | Q2 2026 | Aug 14, 2026 |
| Dafna Capital Management Llc | Buy | +32,400 | — | 32,400 | $703.73K | Q2 2026 | Aug 14, 2026 |
| Adar1 Capital Management, Llc | Buy | +26,000 | — | 26,000 | $564.72K | Q2 2026 | Aug 14, 2026 |
| Burkehill Global Management, Lp | Buy | +25,000 | — | 25,000 | $543.00K | Q2 2026 | Aug 14, 2026 |
| Ghisallo Capital Management Llc | Buy | +25,000 | — | 25,000 | $543.00K | Q2 2026 | Aug 14, 2026 |
| Squarepoint Ops Llc | Buy | +24,753 | — | 24,753 | $537.63K | Q2 2026 | Aug 14, 2026 |
| Xtx Topco Ltd | Buy | +10,983 | — | 10,983 | $238.55K | Q2 2026 | Aug 14, 2026 |
| Weiss Asset Management Lp | Buy | +10,000 | — | 10,000 | $217.20K | Q2 2026 | Aug 14, 2026 |
| Zimmer Partners, Lp | Buy | +10,000 | — | 10,000 | $217.20K | Q2 2026 | Aug 14, 2026 |
| Jones Financial Companies Lllp | Buy | +2,256 | — | 2,256 | $48.28K | Q2 2026 | Aug 14, 2026 |
| Barclays Plc | Buy | +837 | — | 837 | $18.18K | Q2 2026 | Aug 14, 2026 |
Frequently asked questions about SPTX activity
Which institutional owners are buying SPTX?
Institutional owners buying SPTX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in SPTX activity?
"Buy" means an investor increased their reported position in SPTX compared to the prior reporting period. This reflects growing exposure to Seaport Therapeutics, Inc. (SPTX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in SPTX increasing?
Institutional interest in SPTX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.