XILIO THERAPEUTICS INC (XLO) Institutional Ownership Changes & 13F Activity

XILIO THERAPEUTICS INC (XLO). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Orbimed Advisors Llc, Stonepine Capital Management, Llc, Caligan Partners Lp, Adage Capital Partners Gp, L.L.C., and Vanguard Capital Management Llc.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Security National Bank Of Sioux City IowaBuy+321—321$3.08KQ2 2026Sep 18, 2026
Citadel Advisors LlcBuy+25,950—25,950$248.60KQ2 2026Sep 02, 2026
Stonepine Capital Management, LlcBuy+161,832+252.2%225,994$2.17MQ2 2026Aug 17, 2026
Orbimed Advisors LlcBuy+592,300—592,300$5.67MQ2 2026Aug 14, 2026
Adage Capital Partners Gp, L.L.C.Buy+111,541—111,541$1.07MQ2 2026Aug 14, 2026
Bridgeway Capital Management, LlcBuy+17,544—17,544$168.07KQ2 2026Aug 14, 2026
Two Sigma Investments, LpBuy+14,544—14,544$139.33KQ2 2026Aug 14, 2026
Prelude Capital Management, LlcBuy+11,600—11,600$111.13KQ2 2026Aug 14, 2026
Barclays PlcBuy+115—115$1.10KQ2 2026Aug 14, 2026
Jones Financial Companies LllpBuy+29—29$262.00Q2 2026Aug 14, 2026
Vanguard Capital Management LlcBuy+54,857+44.4%178,517$1.71MQ2 2026Aug 13, 2026
Renaissance Technologies LLCBuy+14,587+29.4%64,153$614.59KQ2 2026Aug 13, 2026
Vanguard Fiduciary Trust CoSell-5,881-20.7%22,594$216.45KQ2 2026Aug 13, 2026
Ubs Group AgSell-4,024-99.7%14$134.00Q2 2026Aug 13, 2026
Steward Partners Investment Advisory, LlcBuy+714—714$6.84KQ2 2026Aug 13, 2026
Morgan StanleySell-539-0.9%56,954$545.62KQ2 2026Aug 13, 2026
Geode Capital Management, LlcBuy+1,858+5.0%39,055$374.17KQ2 2026Aug 12, 2026
Blackrock, Inc.Buy+8,757—8,757$83.89KQ2 2026Aug 07, 2026
Gsa Capital Partners LlpSell-3,356-19.8%13,590$130.00KQ2 2026Aug 06, 2026
Caligan Partners LpSell-112,128-100.0%0$0.00Q2 2026May 15, 2026
Fmr LlcSell-36,558-100.0%0$0.00Q2 2026May 15, 2026
Ghisallo Capital Management LlcSell-13,800-100.0%0$0.00Q2 2026May 15, 2026
Royal Bank Of CanadaSell-91-100.0%0$0.00Q2 2026May 15, 2026
Cwm, LlcSell-4,206-100.0%0$0.00Q2 2026May 14, 2026
Aju Ib Investment Co., Ltd.Sell-47,695-100.0%0$0.00Q2 2026May 08, 2026
Vanguard Global Advisers, LlcSell-210-100.0%0$0.00Q2 2026May 08, 2026
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Frequently asked questions about XLO activity

  • Which institutional owners are buying XLO?

    Institutional owners buying XLO include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in XLO activity?

    "Buy" means an investor increased their reported position in XLO compared to the prior reporting period. This reflects growing exposure to XILIO THERAPEUTICS INC (XLO) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in XLO increasing?

    Institutional interest in XLO can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.