XILIO THERAPEUTICS INC (XLO) Institutional Ownership Changes & 13F Activity
XILIO THERAPEUTICS INC (XLO). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Orbimed Advisors Llc, Stonepine Capital Management, Llc, Caligan Partners Lp, Adage Capital Partners Gp, L.L.C., and Vanguard Capital Management Llc.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Security National Bank Of Sioux City Iowa | Buy | +321 | — | 321 | $3.08K | Q2 2026 | Sep 18, 2026 |
| Citadel Advisors Llc | Buy | +25,950 | — | 25,950 | $248.60K | Q2 2026 | Sep 02, 2026 |
| Stonepine Capital Management, Llc | Buy | +161,832 | +252.2% | 225,994 | $2.17M | Q2 2026 | Aug 17, 2026 |
| Orbimed Advisors Llc | Buy | +592,300 | — | 592,300 | $5.67M | Q2 2026 | Aug 14, 2026 |
| Adage Capital Partners Gp, L.L.C. | Buy | +111,541 | — | 111,541 | $1.07M | Q2 2026 | Aug 14, 2026 |
| Bridgeway Capital Management, Llc | Buy | +17,544 | — | 17,544 | $168.07K | Q2 2026 | Aug 14, 2026 |
| Two Sigma Investments, Lp | Buy | +14,544 | — | 14,544 | $139.33K | Q2 2026 | Aug 14, 2026 |
| Prelude Capital Management, Llc | Buy | +11,600 | — | 11,600 | $111.13K | Q2 2026 | Aug 14, 2026 |
| Barclays Plc | Buy | +115 | — | 115 | $1.10K | Q2 2026 | Aug 14, 2026 |
| Jones Financial Companies Lllp | Buy | +29 | — | 29 | $262.00 | Q2 2026 | Aug 14, 2026 |
| Vanguard Capital Management Llc | Buy | +54,857 | +44.4% | 178,517 | $1.71M | Q2 2026 | Aug 13, 2026 |
| Renaissance Technologies LLC | Buy | +14,587 | +29.4% | 64,153 | $614.59K | Q2 2026 | Aug 13, 2026 |
| Vanguard Fiduciary Trust Co | Sell | -5,881 | -20.7% | 22,594 | $216.45K | Q2 2026 | Aug 13, 2026 |
| Ubs Group Ag | Sell | -4,024 | -99.7% | 14 | $134.00 | Q2 2026 | Aug 13, 2026 |
| Steward Partners Investment Advisory, Llc | Buy | +714 | — | 714 | $6.84K | Q2 2026 | Aug 13, 2026 |
| Morgan Stanley | Sell | -539 | -0.9% | 56,954 | $545.62K | Q2 2026 | Aug 13, 2026 |
| Geode Capital Management, Llc | Buy | +1,858 | +5.0% | 39,055 | $374.17K | Q2 2026 | Aug 12, 2026 |
| Blackrock, Inc. | Buy | +8,757 | — | 8,757 | $83.89K | Q2 2026 | Aug 07, 2026 |
| Gsa Capital Partners Llp | Sell | -3,356 | -19.8% | 13,590 | $130.00K | Q2 2026 | Aug 06, 2026 |
| Caligan Partners Lp | Sell | -112,128 | -100.0% | 0 | $0.00 | Q2 2026 | May 15, 2026 |
| Fmr Llc | Sell | -36,558 | -100.0% | 0 | $0.00 | Q2 2026 | May 15, 2026 |
| Ghisallo Capital Management Llc | Sell | -13,800 | -100.0% | 0 | $0.00 | Q2 2026 | May 15, 2026 |
| Royal Bank Of Canada | Sell | -91 | -100.0% | 0 | $0.00 | Q2 2026 | May 15, 2026 |
| Cwm, Llc | Sell | -4,206 | -100.0% | 0 | $0.00 | Q2 2026 | May 14, 2026 |
| Aju Ib Investment Co., Ltd. | Sell | -47,695 | -100.0% | 0 | $0.00 | Q2 2026 | May 08, 2026 |
| Vanguard Global Advisers, Llc | Sell | -210 | -100.0% | 0 | $0.00 | Q2 2026 | May 08, 2026 |
Frequently asked questions about XLO activity
Which institutional owners are buying XLO?
Institutional owners buying XLO include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in XLO activity?
"Buy" means an investor increased their reported position in XLO compared to the prior reporting period. This reflects growing exposure to XILIO THERAPEUTICS INC (XLO) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in XLO increasing?
Institutional interest in XLO can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
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