ENANTA PHARMACEUTICALS INC (ENTA) Top Institutional Shareholders

ENANTA PHARMACEUTICALS INC (ENTA) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $290.60M in ENTA holdings during the latest filing period.

Janus Henderson Group Plc is currently the largest disclosed institutional shareholder of ENTA tracked by InsiderSet, reporting ownership valued at approximately $47.72M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $47.83M, representing an estimated gain of +0.24% since the filing period.

The top 10 institutional shareholders tracked on this page collectively account for approximately 74% of the total disclosed ENTA value among the investors covered in this analysis. Major shareholders include Janus Henderson Group Plc, Blackrock, Inc., Farallon Capital Management Llc, and several other long-term asset managers with concentrated positions in ENANTA PHARMACEUTICALS INC (ENTA).

This page ranks the largest institutional ENTA shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.

Institutional Holders

129

Total Reported Value

$290.60M

Largest Holder

Janus Henderson Group Plc

Largest Position

$47.72M

Insider Transactions (90d)

0

Latest Filing Quarter

Q1 2026

New Institutional Positions

153

Funds Exiting Positions

0

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NameInvestor/ManagerPortfolio %QuantityReported BalanceCurrent Estimated ValueGain/loss Since FilingEstimated Portfolio Performance
Janus Henderson Group Plc0.02%3,784,055$47,716,934$47,830,455+$113,521+0.24%
Blackrock, Inc.0.00%3,103,768$39,200,591$39,231,628+$31,037+0.08%
Farallon Capital Management Llc0.24%2,871,862$36,271,617$36,300,336+$28,719+0.08%
Deep Track Capital, Lp0.51%1,956,867$24,715,230$24,734,799+$19,569+0.08%
Vanguard Capital Management Llc0.00%1,178,049$14,878,759$14,890,539+$11,780+0.08%
Vanguard Portfolio Management Llc0.00%948,904$11,984,658$11,994,147+$9,489+0.08%
Spruce Street Capital Lp2.83%932,598$11,778,713$11,788,039+$9,326+0.08%
Millennium Management Llc0.01%882,097$11,140,885$11,149,706+$8,821+0.08%
Geode Capital Management, Llc0.00%725,061$9,159,559$9,164,771+$5,212+0.06%
Renaissance Technologies LLCJim Simons0.01%665,258$8,402,209$8,408,861+$6,652+0.08%
State Street Corp0.00%562,106$7,099,399$7,105,020+$5,621+0.08%
Hillsdale Investment Management Inc.0.15%435,510$5,500,491$5,504,846+$4,355+0.08%
Aqr Capital Management Llc0.00%313,157$3,955,173$3,958,304+$3,131+0.08%
Morgan Stanley0.00%309,511$3,909,132$3,912,219+$3,087+0.08%
Charles Schwab Investment Management Inc0.00%294,971$3,725,484$3,728,433+$2,949+0.08%
Two Sigma Investments, Lp0.00%267,364$3,376,807$3,379,481+$2,674+0.08%
Goldman Sachs Group Inc0.00%265,088$3,348,062$3,350,712+$2,650+0.08%
Citadel Advisors Llc0.00%262,533$3,315,791$3,318,417+$2,626+0.08%
Northern Trust Corp0.00%240,968$3,043,426$3,045,836+$2,410+0.08%
Marshall Wace, Llp0.00%210,070$2,653,185$2,655,285+$2,100+0.08%
Dimensional Fund Advisors Lp0.00%203,252$2,566,230$2,569,105+$2,875+0.11%
Invesco Ltd.0.00%182,002$2,298,685$2,300,505+$1,820+0.08%
Vanguard Fiduciary Trust Co0.00%175,856$2,221,061$2,222,820+$1,759+0.08%
Eversource Wealth Advisors, Llc0.05%54,587$1,632,606$689,980-$942,626-57.74%
Connor, Clark & Lunn Investment Management Ltd.0.00%125,759$1,588,336$1,589,594+$1,258+0.08%
Opaleye Management Inc.0.21%125,000$1,578,750$1,580,000+$1,250+0.08%
Qube Research & Technologies Ltd0.00%116,961$1,477,217$1,478,387+$1,170+0.08%
Sei Investments Co0.00%109,077$1,377,645$1,378,733+$1,088+0.08%
Panagora Asset Management Inc0.00%89,599$1,131,635$1,132,531+$896+0.08%
Wellington Management Group Llp0.00%74,960$946,745$947,494+$749+0.08%
Russell Investments Group, Ltd.0.00%72,850$914,760$920,824+$6,064+0.66%
D. E. Shaw & Co., Inc.0.00%70,884$895,265$895,974+$709+0.08%
Bank Of New York Mellon Corp0.00%70,783$893,990$894,697+$707+0.08%
Franklin Resources Inc0.00%66,947$845,540$846,210+$670+0.08%
Diadema Partners Lp0.34%64,952$820,344$820,993+$649+0.08%
Ubs Group Ag0.00%63,804$805,844$806,483+$639+0.08%
Trexquant Investment Lp0.01%56,167$709,389$709,951+$562+0.08%
Nuveen, Llc0.00%52,270$660,170$660,693+$523+0.08%
Adar1 Capital Management, Llc0.04%51,357$648,639$649,152+$513+0.08%
Alliancebernstein L.P.0.00%33,740$532,080$426,474-$105,606-19.85%
Informed Momentum Co Llc0.06%40,952$517,224$517,633+$409+0.08%
Campbell & Co Investment Adviser Llc0.03%40,214$507,903$508,305+$402+0.08%
Sio Capital Management, Llc0.07%40,000$505,200$505,600+$400+0.08%
Man Group Plc0.00%39,234$495,525$495,918+$393+0.08%
Ieq Capital, Llc0.00%38,672$488,427$488,814+$387+0.08%
Prudential Financial Inc0.00%37,995$479,877$480,257+$380+0.08%
Quantinno Capital Management Lp0.00%35,122$443,591$443,942+$351+0.08%
Bank Of Montreal0.00%33,868$427,753$428,092+$339+0.08%
Xtx Topco Ltd0.01%33,211$419,455$419,787+$332+0.08%
Rhumbline Advisers0.00%31,403$396,609$396,934+$325+0.08%

Frequently asked questions about ENTA

  • Who owns the most ENTA stock?

    The largest holders of ENTA are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ENANTA PHARMACEUTICALS INC (ENTA).

  • Is ENTA widely held by superinvestors?

    Many widely followed stocks like ENTA appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ENTA is represented among the institutional managers we track.

  • What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?

    Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.