ENTA Institutional Ownership & Shareholders
ENANTA PHARMACEUTICALS INC (ENTA) is currently held by 118 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $355.45M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Janus Henderson Group Plc is currently the largest disclosed institutional shareholder of ENTA tracked by InsiderSet, reporting ownership valued at approximately $47.72M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $40.30M, representing an estimated loss of -15.54% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 71% of the total disclosed ENTA value among the investors covered in this analysis. Major shareholders include Janus Henderson Group Plc, Blackrock, Inc., Krensavage Asset Management, Llc, and several other long-term asset managers with concentrated positions in ENANTA PHARMACEUTICALS INC (ENTA).
This page ranks the largest institutional ENTA shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
118
Total Reported Value
$355.45M
Largest Holder
Janus Henderson Group Plc
Largest Position
$47.72M
Insider Transactions (90d)
1
Latest Filing Quarter
Q2 2026
New Institutional Positions
113
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Janus Henderson Group Plc | 0.02% | 3,784,055 | $47,716,934 | $40,300,186 | -$7,416,748 | -15.54% | |
| Blackrock, Inc. | 0.00% | 3,244,448 | $47,304,051 | $34,553,371 | -$12,750,680 | -26.95% | |
| Krensavage Asset Management, Llc | 15.88% | 2,866,138 | $41,788,000 | $30,524,370 | -$11,263,630 | -26.95% | |
| Deep Track Capital, Lp | 0.31% | 1,444,167 | $21,055,955 | $15,380,379 | -$5,675,576 | -26.95% | |
| Adar1 Capital Management, Llc | 0.92% | 1,344,510 | $19,602,956 | $14,319,032 | -$5,283,925 | -26.95% | |
| Vanguard Capital Management Llc | 0.00% | 1,211,769 | $17,667,592 | $12,905,340 | -$4,762,252 | -26.95% | |
| Spruce Street Capital Lp | 3.11% | 1,088,731 | $15,873,698 | $11,594,985 | -$4,278,713 | -26.95% | |
| Acadian Asset Management Llc | 0.02% | 1,078,317 | $15,706,000 | $11,484,076 | -$4,221,924 | -26.88% | |
| Vanguard Portfolio Management Llc | 0.00% | 1,011,494 | $14,747,583 | $10,772,411 | -$3,975,172 | -26.95% | |
| Geode Capital Management, Llc | 0.00% | 776,634 | $11,325,842 | $8,271,152 | -$3,054,690 | -26.97% | |
| Millennium Management Llc | 0.01% | 643,967 | $9,389,039 | $6,858,249 | -$2,530,790 | -26.95% | |
| State Street Corp | 0.00% | 576,117 | $8,399,786 | $6,135,646 | -$2,264,140 | -26.95% | |
| Renaissance Technologies LLC | Jim Simons | 0.01% | 557,600 | $8,129,808 | $5,938,440 | -$2,191,368 | -26.95% |
| Hillsdale Investment Management Inc. | 0.16% | 468,000 | $6,823,440 | $4,984,200 | -$1,839,240 | -26.95% | |
| Goldman Sachs Group Inc | 0.00% | 464,649 | $6,774,583 | $4,948,512 | -$1,826,071 | -26.95% | |
| Morgan Stanley | 0.00% | 315,729 | $4,603,338 | $3,362,514 | -$1,240,824 | -26.95% | |
| Charles Schwab Investment Management Inc | 0.00% | 301,151 | $4,390,782 | $3,207,258 | -$1,183,524 | -26.95% | |
| Dimensional Fund Advisors Lp | 0.00% | 282,682 | $4,121,427 | $3,010,563 | -$1,110,864 | -26.95% | |
| Northern Trust Corp | 0.00% | 259,696 | $3,786,368 | $2,765,762 | -$1,020,606 | -26.95% | |
| Summittx Capital, L.P. | 0.10% | 257,702 | $3,757,295 | $2,744,526 | -$1,012,769 | -26.95% | |
| Aqr Capital Management Llc | 0.00% | 256,870 | $3,745,165 | $2,735,666 | -$1,009,500 | -26.95% | |
| Vanguard Fiduciary Trust Co | 0.00% | 185,618 | $2,706,310 | $1,976,832 | -$729,478 | -26.95% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | 153,008 | $2,230,857 | $1,629,535 | -$601,322 | -26.95% | |
| Rockefeller Capital Management L.P. | 0.00% | 150,546 | $2,194,960 | $1,603,315 | -$591,645 | -26.95% | |
| Marshall Wace, Llp | 0.00% | 131,995 | $1,924,487 | $1,405,747 | -$518,740 | -26.95% | |
| Opaleye Management Inc. | 0.17% | 125,000 | $1,822,500 | $1,331,250 | -$491,250 | -26.95% | |
| Jpmorgan Chase & Co | 0.00% | 96,764 | $1,404,045 | $1,030,537 | -$373,508 | -26.60% | |
| Russell Investments Group, Ltd. | 0.00% | 84,231 | $1,227,255 | $897,060 | -$330,195 | -26.91% | |
| Wellington Management Group Llp | 0.00% | 81,633 | $1,190,209 | $869,391 | -$320,818 | -26.95% | |
| Qube Research & Technologies Ltd | 0.00% | 81,005 | $1,181,053 | $862,703 | -$318,350 | -26.95% | |
| Bank Of New York Mellon Corp | 0.00% | 76,756 | $1,119,105 | $817,451 | -$301,654 | -26.95% | |
| Xtx Topco Ltd | 0.01% | 75,468 | $1,100,323 | $803,734 | -$296,589 | -26.95% | |
| Two Sigma Investments, Lp | 0.00% | 71,162 | $1,037,542 | $757,875 | -$279,667 | -26.95% | |
| Campbell & Co Investment Adviser Llc | 0.05% | 70,764 | $1,031,739 | $753,637 | -$278,102 | -26.95% | |
| Trexquant Investment Lp | 0.01% | 69,613 | $1,014,958 | $741,378 | -$273,580 | -26.95% | |
| Sei Investments Co | 0.00% | 66,685 | $972,264 | $710,195 | -$262,069 | -26.95% | |
| Ubs Group Ag | 0.00% | 64,319 | $937,771 | $684,997 | -$252,774 | -26.95% | |
| Invesco Ltd. | 0.00% | 59,530 | $867,948 | $633,995 | -$233,954 | -26.95% | |
| Nuveen, Llc | 0.00% | 57,131 | $832,970 | $608,445 | -$224,525 | -26.95% | |
| Citadel Advisors Llc | 0.00% | 50,844 | $741,305 | $541,489 | -$199,816 | -26.95% | |
| Quantinno Capital Management Lp | 0.00% | 45,109 | $657,689 | $480,411 | -$177,278 | -26.95% | |
| State Of Wisconsin Investment Board | 0.00% | 40,908 | $596,439 | $435,670 | -$160,769 | -26.95% | |
| Prudential Financial Inc | 0.00% | 39,865 | $581,232 | $424,562 | -$156,670 | -26.95% | |
| Ieq Capital, Llc | 0.00% | 38,508 | $561,447 | $410,110 | -$151,337 | -26.95% | |
| Panagora Asset Management Inc | 0.00% | 34,789 | $507,224 | $370,503 | -$136,721 | -26.95% | |
| Rhumbline Advisers | 0.00% | 34,571 | $504,034 | $368,181 | -$135,853 | -26.95% | |
| D. E. Shaw & Co., Inc. | 0.00% | 34,539 | $503,579 | $367,840 | -$135,739 | -26.95% | |
| Bank Of Montreal | 0.00% | 33,868 | $493,795 | $360,694 | -$133,101 | -26.95% | |
| Alliancebernstein L.P. | 0.00% | 37,900 | $478,677 | $403,635 | -$75,042 | -15.68% | |
| Gsa Capital Partners Llp | 0.03% | 32,486 | $474,000 | $345,976 | -$128,024 | -27.01% |
Frequently asked questions about ENTA
Who are the largest institutional holders of ENTA?
The largest institutional holders of ENTA reported in the latest SEC Form 13F filings include Janus Henderson Group Plc, Blackrock, Inc., Krensavage Asset Management, Llc, Deep Track Capital, Lp, and Adar1 Capital Management, Llc. InsiderSet ranks institutional holders by their latest reported ENTA position.
What is ENTA institutional ownership?
This page tracks ENTA positions reported by institutional investment managers through SEC Form 13F. ENANTA PHARMACEUTICALS INC (ENTA) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own ENTA?
InsiderSet currently tracks 118 institutional managers reporting ENTA holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of ENTA shareholders.
How much ENTA stock do institutions own?
Institutional investment managers disclosed approximately $355.45M in ENTA holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was ENTA institutional ownership last updated?
The latest ENTA institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional ENTA holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its ENTA position after the reporting date.
Are institutions buying or selling ENTA?
Institutional buying and selling can be analyzed by comparing ENTA positions across consecutive 13F reporting periods. InsiderSet's ENTA Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View ENTA ownership changes.
How has ENTA institutional ownership changed over time?
InsiderSet tracks ENTA institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.