ENANTA PHARMACEUTICALS INC (ENTA) Institutional Ownership Changes & 13F Activity
ENANTA PHARMACEUTICALS INC (ENTA). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Janus Henderson Group Plc, Krensavage Asset Management, Llc, Millennium Management Llc, Point72 Asset Management, L.P., and Two Sigma Investments, Lp.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Algert Global Llc | Sell | -11,106 | -100.0% | 0 | $0.00 | Q4 2025 | Aug 11, 2026 |
| Seven Fleet Capital Management Lp | Buy | +2,270 | — | 2,270 | $35.80K | Q4 2025 | Feb 26, 2026 |
| Virtu Financial Llc | Buy | +13,967 | — | 13,967 | $220.00K | Q4 2025 | Feb 23, 2026 |
| Sunbelt Securities, Inc. | Buy | +63 | — | 63 | $994.00 | Q4 2025 | Feb 20, 2026 |
| Krensavage Asset Management, Llc | Buy | +2,766,390 | — | 2,766,390 | $43.63M | Q4 2025 | Feb 18, 2026 |
| Janus Henderson Group Plc | Buy | +3,729,659 | — | 3,729,659 | $58.76M | Q4 2025 | Feb 17, 2026 |
| Millennium Management Llc | Buy | +670,428 | — | 670,428 | $10.57M | Q4 2025 | Feb 17, 2026 |
| Point72 Asset Management, L.P. | Buy | +438,939 | — | 438,939 | $6.92M | Q4 2025 | Feb 17, 2026 |
| Two Sigma Investments, Lp | Buy | +285,448 | — | 285,448 | $4.50M | Q4 2025 | Feb 17, 2026 |
| Aqr Capital Management Llc | Buy | +234,835 | — | 234,835 | $3.70M | Q4 2025 | Feb 17, 2026 |
| Northern Trust Corp | Buy | +229,889 | — | 229,889 | $3.63M | Q4 2025 | Feb 17, 2026 |
| D. E. Shaw & Co., Inc. | Buy | +167,714 | — | 167,714 | $2.64M | Q4 2025 | Feb 17, 2026 |
| Two Sigma Advisers, Lp | Buy | +143,300 | — | 143,300 | $2.26M | Q4 2025 | Feb 17, 2026 |
| Citadel Advisors Llc | Buy | +93,158 | — | 93,158 | $1.47M | Q4 2025 | Feb 17, 2026 |
| Opaleye Management Inc. | Buy | +75,000 | — | 75,000 | $1.18M | Q4 2025 | Feb 17, 2026 |
| Pdt Partners, Llc | Buy | +69,197 | — | 69,197 | $1.09M | Q4 2025 | Feb 17, 2026 |
| Bank Of America Corp | Buy | +65,978 | — | 65,978 | $1.04M | Q4 2025 | Feb 17, 2026 |
| Diadema Partners Lp | Buy | +65,138 | — | 65,138 | $1.03M | Q4 2025 | Feb 17, 2026 |
| Wellington Management Group Llp | Buy | +63,219 | — | 63,219 | $996.96K | Q4 2025 | Feb 17, 2026 |
| Susquehanna Fundamental Investments, Llc | Buy | +50,434 | — | 50,434 | $795.34K | Q4 2025 | Feb 17, 2026 |
| Man Group Plc | Buy | +43,847 | — | 43,847 | $691.47K | Q4 2025 | Feb 17, 2026 |
| Adar1 Capital Management, Llc | Buy | +41,357 | — | 41,357 | $652.20K | Q4 2025 | Feb 17, 2026 |
| Sio Capital Management, Llc | Buy | +40,000 | — | 40,000 | $630.80K | Q4 2025 | Feb 17, 2026 |
| Alliancebernstein L.P. | Buy | +33,740 | — | 33,740 | $532.08K | Q4 2025 | Feb 17, 2026 |
| Quantinno Capital Management Lp | Buy | +33,495 | — | 33,495 | $528.22K | Q4 2025 | Feb 17, 2026 |
| Qube Research & Technologies Ltd | Buy | +32,389 | — | 32,389 | $510.77K | Q4 2025 | Feb 17, 2026 |
| Bridgeway Capital Management, Llc | Buy | +29,700 | — | 29,700 | $468.37K | Q4 2025 | Feb 17, 2026 |
| State Of Wisconsin Investment Board | Buy | +18,608 | — | 18,608 | $293.45K | Q4 2025 | Feb 17, 2026 |
| Persistent Asset Partners Ltd | Buy | +17,466 | — | 17,466 | $275.44K | Q4 2025 | Feb 17, 2026 |
| Price T Rowe Associates Inc | Buy | +14,410 | — | 14,410 | $228.00K | Q4 2025 | Feb 17, 2026 |
Frequently asked questions about ENTA activity
Which institutional owners are buying ENTA?
Institutional owners buying ENTA include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in ENTA activity?
"Buy" means an investor increased their reported position in ENTA compared to the prior reporting period. This reflects growing exposure to ENANTA PHARMACEUTICALS INC (ENTA) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in ENTA increasing?
Institutional interest in ENTA can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related ENTA Institutional Insights
- ENTA Overview
- ENTA 13F Institutional Holders
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- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
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- ENTA Insider Trading & SEC Form 4 Activity
- ENTA Articles
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