ETON Institutional Ownership & Shareholders
ETON PHARMACEUTICALS INC (ETON) is currently held by 182 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $741.19M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Opaleye Management Inc. is currently the largest disclosed institutional shareholder of ETON tracked by InsiderSet, reporting ownership valued at approximately $103.53M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $149.23M, representing an estimated gain of +44.14% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 60% of the total disclosed ETON value among the investors covered in this analysis. Major shareholders include Opaleye Management Inc., Ecor1 Capital, Llc, Blackrock, Inc., and several other long-term asset managers with concentrated positions in ETON PHARMACEUTICALS INC (ETON).
This page ranks the largest institutional ETON shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
182
Total Reported Value
$741.19M
Largest Holder
Opaleye Management Inc.
Largest Position
$103.53M
Insider Transactions (90d)
11
Latest Filing Quarter
Q2 2026
New Institutional Positions
105
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Opaleye Management Inc. | 9.38% | 2,860,000 | $103,532,000 | $149,234,800 | +$45,702,800 | +44.14% | |
| Ecor1 Capital, Llc | 3.90% | 2,171,938 | $78,624,156 | $113,331,725 | +$34,707,569 | +44.14% | |
| Blackrock, Inc. | 0.00% | 1,895,833 | $68,629,156 | $98,924,566 | +$30,295,410 | +44.14% | |
| Nantahala Capital Management, Llc | 2.57% | 1,175,951 | $42,569,426 | $61,361,123 | +$18,791,697 | +44.14% | |
| Vanguard Capital Management Llc | 0.00% | 976,570 | $35,351,834 | $50,957,423 | +$15,605,589 | +44.14% | |
| Morgan Stanley | 0.00% | 767,972 | $27,800,585 | $40,072,779 | +$12,272,194 | +44.14% | |
| State Street Corp | 0.00% | 701,786 | $25,404,653 | $36,619,193 | +$11,214,540 | +44.14% | |
| Geode Capital Management, Llc | 0.00% | 652,303 | $23,618,970 | $34,037,171 | +$10,418,201 | +44.11% | |
| Westside Investment Management, Inc. | 2.63% | 401,385 | $20,669,280 | $20,944,269 | +$274,989 | +1.33% | |
| Oberweis Asset Management Inc/ | 0.38% | 501,600 | $18,157,920 | $26,173,488 | +$8,015,568 | +44.14% | |
| National Philanthropic Trust | 0.26% | 492,112 | $17,814,454 | $25,678,404 | +$7,863,950 | +44.14% | |
| Pillsbury Lake Capital Llc | 3.85% | 387,157 | $14,015,083 | $20,201,852 | +$6,186,769 | +44.14% | |
| Nuveen, Llc | 0.00% | 375,707 | $13,600,593 | $19,604,391 | +$6,003,798 | +44.14% | |
| Bnp Paribas Financial Markets | 0.01% | 322,466 | $11,673,269 | $16,826,276 | +$5,153,007 | +44.14% | |
| Woodline Partners Lp | 0.03% | 310,879 | $11,253,820 | $16,221,666 | +$4,967,846 | +44.14% | |
| Thompson Siegel & Walmsley Llc | 0.19% | 297,232 | $10,760,000 | $15,509,566 | +$4,749,566 | +44.14% | |
| Northern Trust Corp | 0.00% | 255,849 | $9,261,733 | $13,350,201 | +$4,088,468 | +44.14% | |
| Marshall Wace, Llp | 0.01% | 249,182 | $9,020,387 | $13,002,317 | +$3,981,930 | +44.14% | |
| Wasatch Advisors Lp | 0.06% | 157,802 | $8,125,225 | $8,234,108 | +$108,883 | +1.34% | |
| Panoramic Capital, Llc | 3.24% | 208,192 | $7,536,550 | $10,863,459 | +$3,326,909 | +44.14% | |
| Vanguard Portfolio Management Llc | 0.00% | 194,591 | $7,044,194 | $10,153,758 | +$3,109,564 | +44.14% | |
| Jpmorgan Chase & Co | 0.00% | 191,635 | $7,038,753 | $9,999,514 | +$2,960,761 | +42.06% | |
| D. E. Shaw & Co., Inc. | 0.00% | 188,452 | $6,821,962 | $9,833,425 | +$3,011,463 | +44.14% | |
| Jane Street Group, Llc | 0.00% | 185,697 | $6,722,232 | $9,689,669 | +$2,967,437 | +44.14% | |
| Lumbard & Kellner, Llc | 1.93% | 175,909 | $6,367,906 | $9,178,932 | +$2,811,026 | +44.14% | |
| Cannell Capital Llc | 4.32% | 170,747 | $6,181,041 | $8,909,578 | +$2,728,537 | +44.14% | |
| Norges Bank | 0.00% | 169,500 | $6,135,900 | $8,844,510 | +$2,708,610 | +44.14% | |
| Vanguard Fiduciary Trust Co | 0.00% | 168,539 | $6,101,112 | $8,794,365 | +$2,693,253 | +44.14% | |
| Informed Momentum Co Llc | 0.51% | 158,045 | $5,721,229 | $8,246,788 | +$2,525,559 | +44.14% | |
| Prospect Capital Advisors, Llc | 2.58% | 157,200 | $5,690,640 | $8,202,696 | +$2,512,056 | +44.14% | |
| Aristides Capital Llc | 1.35% | 145,410 | $5,263,842 | $7,587,494 | +$2,323,652 | +44.14% | |
| Bank Of America Corp | 0.00% | 142,257 | $5,149,704 | $7,422,970 | +$2,273,266 | +44.14% | |
| Prelude Capital Management, Llc | 0.37% | 137,572 | $4,980,106 | $7,178,507 | +$2,198,401 | +44.14% | |
| Goldman Sachs Group Inc | 0.00% | 132,583 | $4,799,505 | $6,918,181 | +$2,118,676 | +44.14% | |
| Bridge City Capital, Llc | 0.93% | 86,767 | $4,467,633 | $4,527,502 | +$59,869 | +1.34% | |
| Bank Of New York Mellon Corp | 0.00% | 118,249 | $4,280,614 | $6,170,233 | +$1,889,619 | +44.14% | |
| Two Sigma Investments, Lp | 0.00% | 116,291 | $4,209,734 | $6,068,064 | +$1,858,330 | +44.14% | |
| Wells Fargo & Company/Mn | 0.00% | 114,655 | $4,150,510 | $5,982,698 | +$1,832,188 | +44.14% | |
| Principal Financial Group Inc | 0.00% | 64,335 | $3,312,609 | $3,357,000 | +$44,391 | +1.34% | |
| Walleye Capital Llc | 0.01% | 86,249 | $3,122,214 | $4,500,473 | +$1,378,259 | +44.14% | |
| Charles Schwab Investment Management Inc | 0.00% | 77,032 | $2,788,558 | $4,019,530 | +$1,230,972 | +44.14% | |
| Wellington Management Group Llp | 0.00% | 76,103 | $2,754,928 | $3,971,055 | +$1,216,127 | +44.14% | |
| Diametric Capital, Lp | 0.28% | 73,101 | $2,646,256 | $3,814,410 | +$1,168,154 | +44.14% | |
| Numerai Gp Llc | 0.21% | 70,114 | $2,538,127 | $3,658,549 | +$1,120,422 | +44.14% | |
| Ubs Group Ag | 0.00% | 65,424 | $2,368,349 | $3,413,824 | +$1,045,475 | +44.14% | |
| Robeco Institutional Asset Management B.V. | 0.00% | 45,993 | $2,368,179 | $2,399,915 | +$31,736 | +1.34% | |
| Squarepoint Ops Llc | 0.00% | 59,562 | $2,156,144 | $3,107,945 | +$951,801 | +44.14% | |
| Boothbay Fund Management, Llc | 0.04% | 57,516 | $2,082,079 | $3,001,185 | +$919,106 | +44.14% | |
| Barclays Plc | 0.00% | 56,181 | $2,033,751 | $2,931,525 | +$897,774 | +44.14% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 52,300 | $1,893,260 | $2,729,014 | +$835,754 | +44.14% |
Frequently asked questions about ETON
Who are the largest institutional holders of ETON?
The largest institutional holders of ETON reported in the latest SEC Form 13F filings include Opaleye Management Inc., Ecor1 Capital, Llc, Blackrock, Inc., Nantahala Capital Management, Llc, and Vanguard Capital Management Llc. InsiderSet ranks institutional holders by their latest reported ETON position.
What is ETON institutional ownership?
This page tracks ETON positions reported by institutional investment managers through SEC Form 13F. ETON PHARMACEUTICALS INC (ETON) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own ETON?
InsiderSet currently tracks 182 institutional managers reporting ETON holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of ETON shareholders.
How much ETON stock do institutions own?
Institutional investment managers disclosed approximately $741.19M in ETON holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was ETON institutional ownership last updated?
The latest ETON institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional ETON holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its ETON position after the reporting date.
Are institutions buying or selling ETON?
Institutional buying and selling can be analyzed by comparing ETON positions across consecutive 13F reporting periods. InsiderSet's ETON Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View ETON ownership changes.
How has ETON institutional ownership changed over time?
InsiderSet tracks ETON institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.