ETON PHARMACEUTICALS INC (ETON) Institutional Shareholders
ETON PHARMACEUTICALS INC (ETON) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $429.42M in ETON holdings during the latest filing period.
Opaleye Management Inc. is currently the largest disclosed institutional shareholder of ETON tracked by InsiderSet, reporting ownership valued at approximately $70.58M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $132.76M, representing an estimated gain of +88.09% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 67% of the total disclosed ETON value among the investors covered in this analysis. Major shareholders include Opaleye Management Inc., Ecor1 Capital, Llc, Blackrock, Inc., and several other long-term asset managers with concentrated positions in ETON PHARMACEUTICALS INC (ETON).
This page ranks the largest institutional ETON shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
124
Total Reported Value
$429.42M
Largest Holder
Opaleye Management Inc.
Largest Position
$70.58M
Insider Transactions (90d)
16
Latest Filing Quarter
Q2 2026
New Institutional Positions
145
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Opaleye Management Inc. | 9.30% | 2,860,000 | $70,584,800 | $132,761,200 | +$62,176,400 | +88.09% | |
| Ecor1 Capital, Llc | 2.29% | 2,171,938 | $53,603,430 | $100,821,362 | +$47,217,932 | +88.09% | |
| Blackrock, Inc. | 0.00% | 1,717,286 | $42,382,617 | $79,716,416 | +$37,333,799 | +88.09% | |
| Nantahala Capital Management, Llc | 1.81% | 1,175,951 | $29,022,471 | $54,587,645 | +$25,565,174 | +88.09% | |
| Vanguard Capital Management Llc | 0.00% | 994,089 | $24,534,117 | $46,145,611 | +$21,611,494 | +88.09% | |
| Westside Investment Management, Inc. | 2.05% | 431,160 | $15,608,010 | $20,014,447 | +$4,406,437 | +28.23% | |
| Geode Capital Management, Llc | 0.00% | 577,666 | $14,260,695 | $26,815,256 | +$12,554,561 | +88.04% | |
| State Street Corp | 0.00% | 530,215 | $13,085,706 | $24,612,580 | +$11,526,874 | +88.09% | |
| Morgan Stanley | 0.00% | 477,957 | $11,795,980 | $22,186,764 | +$10,390,784 | +88.09% | |
| Oberweis Asset Management Inc/ | 0.32% | 439,300 | $10,841,924 | $20,392,306 | +$9,550,382 | +88.09% | |
| Pillsbury Lake Capital Llc | 4.08% | 364,954 | $9,007,065 | $16,941,165 | +$7,934,100 | +88.09% | |
| Cannell Capital Llc | 5.48% | 341,985 | $8,440,190 | $15,874,944 | +$7,434,754 | +88.09% | |
| Bnp Paribas Financial Markets | 0.00% | 302,108 | $7,456,025 | $14,023,853 | +$6,567,828 | +88.09% | |
| Northern Trust Corp | 0.00% | 237,832 | $5,869,693 | $11,040,161 | +$5,170,468 | +88.09% | |
| Goldman Sachs Group Inc | 0.00% | 217,446 | $5,366,567 | $10,093,843 | +$4,727,276 | +88.09% | |
| Prelude Capital Management, Llc | 0.36% | 188,802 | $4,659,633 | $8,764,189 | +$4,104,556 | +88.09% | |
| Aristides Capital Llc | 1.52% | 186,041 | $4,591,492 | $8,636,023 | +$4,044,531 | +88.09% | |
| Panoramic Capital, Llc | 3.21% | 185,000 | $4,565,800 | $8,587,700 | +$4,021,900 | +88.09% | |
| Lumbard & Kellner, Llc | 1.50% | 175,911 | $4,341,483 | $8,165,789 | +$3,824,306 | +88.09% | |
| Woodline Partners Lp | 0.02% | 170,699 | $4,212,851 | $7,923,848 | +$3,710,997 | +88.09% | |
| Ubs Group Ag | 0.00% | 168,958 | $4,169,883 | $7,843,030 | +$3,673,147 | +88.09% | |
| Soleus Capital Management, L.P. | 0.17% | 166,381 | $4,106,283 | $7,723,406 | +$3,617,123 | +88.09% | |
| Vanguard Fiduciary Trust Co | 0.00% | 164,715 | $4,065,166 | $7,646,070 | +$3,580,904 | +88.09% | |
| Renaissance Technologies LLC | Jim Simons | 0.01% | 163,321 | $4,030,762 | $7,581,361 | +$3,550,599 | +88.09% |
| Diametric Capital, Lp | 1.01% | 156,926 | $3,872,933 | $7,284,505 | +$3,411,572 | +88.09% | |
| Vanguard Portfolio Management Llc | 0.00% | 151,748 | $3,745,141 | $7,044,142 | +$3,299,001 | +88.09% | |
| Bank Of America Corp | 0.00% | 144,367 | $3,562,978 | $6,701,516 | +$3,138,538 | +88.09% | |
| Wasatch Advisors Lp | 0.02% | 92,742 | $3,357,260 | $4,305,084 | +$947,824 | +28.23% | |
| Walleye Capital Llc | 0.01% | 86,249 | $3,122,214 | $4,003,679 | +$881,465 | +28.23% | |
| Bank Of New York Mellon Corp | 0.00% | 111,255 | $2,745,772 | $5,164,457 | +$2,418,685 | +88.09% | |
| Citadel Advisors Llc | 0.00% | 107,815 | $2,660,875 | $5,004,772 | +$2,343,897 | +88.09% | |
| Two Sigma Investments, Lp | 0.00% | 106,393 | $2,625,779 | $4,938,763 | +$2,312,984 | +88.09% | |
| Jane Street Group, Llc | 0.00% | 95,420 | $2,354,965 | $4,429,396 | +$2,074,431 | +88.09% | |
| National Philanthropic Trust | 0.06% | 492,112 | $2,155,451 | $22,843,839 | +$20,688,388 | +959.82% | |
| Marshall Wace, Llp | 0.00% | 82,721 | $2,041,554 | $3,839,909 | +$1,798,355 | +88.09% | |
| Wellington Management Group Llp | 0.00% | 70,124 | $1,730,660 | $3,255,156 | +$1,524,496 | +88.09% | |
| Charles Schwab Investment Management Inc | 0.00% | 68,795 | $1,697,861 | $3,193,464 | +$1,495,603 | +88.09% | |
| Sei Investments Co | 0.00% | 58,034 | $1,432,279 | $2,693,938 | +$1,261,659 | +88.09% | |
| Nuveen, Llc | 0.00% | 57,950 | $1,430,206 | $2,690,039 | +$1,259,833 | +88.09% | |
| Boothbay Fund Management, Llc | 0.03% | 55,605 | $1,372,331 | $2,581,184 | +$1,208,853 | +88.09% | |
| Xtx Topco Ltd | 0.02% | 51,772 | $1,277,733 | $2,403,256 | +$1,125,523 | +88.09% | |
| Barclays Plc | 0.00% | 49,374 | $1,218,550 | $2,291,941 | +$1,073,391 | +88.09% | |
| Y-Intercept (Hong Kong) Ltd | 0.02% | 33,542 | $1,214,220 | $1,557,020 | +$342,800 | +28.23% | |
| Informed Momentum Co Llc | 0.14% | 48,623 | $1,200,016 | $2,257,080 | +$1,057,064 | +88.09% | |
| New York State Common Retirement Fund | 0.00% | 32,779 | $1,186,600 | $1,521,601 | +$335,001 | +28.23% | |
| Riggs Asset Managment Co. Inc. | 0.21% | 32,046 | $1,160,065 | $1,487,575 | +$327,510 | +28.23% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | 42,693 | $1,053,663 | $1,981,809 | +$928,146 | +88.09% | |
| Juncture Wealth Strategies, Llc | 0.27% | 28,849 | $1,044,334 | $1,339,171 | +$294,837 | +28.23% | |
| Anchor Capital Advisors Llc | 0.03% | 40,858 | $1,008,375 | $1,896,628 | +$888,253 | +88.09% | |
| Manatuck Hill Partners, Llc | 0.32% | 40,000 | $987,200 | $1,856,800 | +$869,600 | +88.09% |
Frequently asked questions about ETON
Who owns the most ETON stock?
The largest holders of ETON are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for ETON PHARMACEUTICALS INC (ETON).
Is ETON widely held by superinvestors?
Many widely followed stocks like ETON appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly ETON is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.