SKYE Institutional Ownership & Shareholders
SKYE BIOSCIENCE INC (SKYE) is currently held by 35 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $11.11M based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
5Am Venture Management, Llc is currently the largest disclosed institutional shareholder of SKYE tracked by InsiderSet, reporting ownership valued at approximately $6.71M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $12.39M, representing an estimated gain of +84.62% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 98% of the total disclosed SKYE value among the investors covered in this analysis. Major shareholders include 5Am Venture Management, Llc, Versant Venture Management, Llc, Baker Bros. Advisors Lp, and several other long-term asset managers with concentrated positions in SKYE BIOSCIENCE INC (SKYE).
This page ranks the largest institutional SKYE shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
35
Total Reported Value
$11.11M
Largest Holder
5Am Venture Management, Llc
Largest Position
$6.71M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
57
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| 5Am Venture Management, Llc | 2.33% | 9,681,763 | $6,712,366 | $12,392,657 | +$5,680,291 | +84.62% | |
| Versant Venture Management, Llc | 0.86% | 2,007,704 | $1,391,941 | $2,569,861 | +$1,177,920 | +84.62% | |
| Baker Bros. Advisors Lp | 0.01% | 1,575,243 | $1,092,116 | $2,016,311 | +$924,195 | +84.62% | |
| Vanguard Capital Management Llc | 0.00% | 763,882 | $529,370 | $977,769 | +$448,399 | +84.70% | |
| Sphera Funds Management Ltd. | 0.07% | 678,928 | $470,701 | $869,028 | +$398,327 | +84.62% | |
| Platinum Investment Management Ltd | 0.04% | 233,095 | $161,605 | $298,362 | +$136,757 | +84.62% | |
| Blackrock, Inc. | 0.00% | 232,874 | $161,452 | $298,079 | +$136,627 | +84.62% | |
| Geode Capital Management, Llc | 0.00% | 218,055 | $151,232 | $279,110 | +$127,878 | +84.56% | |
| Millennium Management Llc | 0.00% | 198,524 | $137,637 | $254,111 | +$116,474 | +84.62% | |
| Vanguard Fiduciary Trust Co | 0.00% | 104,229 | $72,231 | $133,413 | +$61,182 | +84.70% | |
| State Street Corp | 0.00% | 73,830 | $51,186 | $94,502 | +$43,316 | +84.63% | |
| Ubs Group Ag | 0.00% | 73,800 | $51,143 | $94,464 | +$43,321 | +84.71% | |
| Northern Trust Corp | 0.00% | 56,327 | $39,052 | $72,099 | +$33,047 | +84.62% | |
| Qube Research & Technologies Ltd | 0.00% | 43,082 | $29,869 | $55,145 | +$25,276 | +84.62% | |
| Simplex Trading, Llc | 0.00% | 26,976 | $18,702 | $34,529 | +$15,827 | +84.63% | |
| Xtx Topco Ltd | 0.00% | 20,993 | $14,554 | $26,871 | +$12,317 | +84.63% | |
| Engineers Gate Manager Lp | 0.00% | 20,194 | $14,001 | $25,848 | +$11,847 | +84.62% | |
| Group One Trading Llc | 0.00% | 4,589 | $3,182 | $5,874 | +$2,692 | +84.60% | |
| Vanguard Global Advisers, Llc | 0.00% | 4,557 | $3,158 | $5,833 | +$2,675 | +84.70% | |
| Morgan Stanley | 0.00% | 2,469 | $1,711 | $3,160 | +$1,449 | +84.71% | |
| Barclays Plc | 0.00% | 655 | $455 | $838 | +$383 | +84.26% | |
| Osaic Holdings, Inc. | 0.00% | 600 | $413 | $768 | +$355 | +85.96% | |
| National Bank Of Canada | 0.00% | 400 | $275 | $512 | +$237 | +86.18% | |
| Jpmorgan Chase & Co | 0.00% | 66 | $44 | $84 | +$40 | +92.00% | |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | 52 | $36 | $67 | +$31 | +84.89% | |
| Federation Des Caisses Desjardins Du Quebec | 0.00% | 51 | $35 | $65 | +$30 | +86.51% | |
| Rockefeller Capital Management L.P. | 0.00% | 39 | $27 | $50 | +$23 | +84.89% | |
| Optiver Holding B.V. | 0.00% | 20 | $14 | $26 | +$12 | +82.86% | |
| Jones Financial Companies Lllp | 0.00% | 8 | $5 | $10 | +$5 | +104.80% | |
| Plante Moran Financial Advisors, Llc | 0.00% | 3 | $2 | $4 | +$2 | +92.00% | |
| Fmr Llc | 0.00% | 1 | $1 | $1 | +$0 | +28.00% | |
| Harbour Investments, Inc. | 0.00% | 1 | $1 | $1 | +$0 | +28.00% | |
| Leo H. Evart, Inc. | 0.00% | 1 | $1 | $1 | +$0 | +28.00% | |
| Mcguire Capital Advisors Inc | 0.00% | 2 | $1 | $3 | +$2 | +156.00% | |
| Wells Fargo & Company/Mn | 0.00% | 1 | $1 | $1 | +$0 | +28.00% |
Frequently asked questions about SKYE
Who are the largest institutional holders of SKYE?
The largest institutional holders of SKYE reported in the latest SEC Form 13F filings include 5Am Venture Management, Llc, Versant Venture Management, Llc, Baker Bros. Advisors Lp, Vanguard Capital Management Llc, and Sphera Funds Management Ltd.. InsiderSet ranks institutional holders by their latest reported SKYE position.
What is SKYE institutional ownership?
This page tracks SKYE positions reported by institutional investment managers through SEC Form 13F. SKYE BIOSCIENCE INC (SKYE) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own SKYE?
InsiderSet currently tracks 35 institutional managers reporting SKYE holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of SKYE shareholders.
How much SKYE stock do institutions own?
Institutional investment managers disclosed approximately $11.11M in SKYE holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was SKYE institutional ownership last updated?
The latest SKYE institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional SKYE holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its SKYE position after the reporting date.
Are institutions buying or selling SKYE?
Institutional buying and selling can be analyzed by comparing SKYE positions across consecutive 13F reporting periods. InsiderSet's SKYE Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View SKYE ownership changes.
How has SKYE institutional ownership changed over time?
InsiderSet tracks SKYE institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.