STOKE THERAPEUTICS INC (STOK) Top Institutional Shareholders
STOKE THERAPEUTICS INC (STOK) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $2.18B in STOK holdings during the latest filing period.
Rtw Investments, Lp is currently the largest disclosed institutional shareholder of STOK tracked by InsiderSet, reporting ownership valued at approximately $183.10M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $170.17M, representing an estimated loss of -7.06% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 61% of the total disclosed STOK value among the investors covered in this analysis. Major shareholders include Rtw Investments, Lp, Blackrock, Inc., Fmr Llc, and several other long-term asset managers with concentrated positions in STOKE THERAPEUTICS INC (STOK).
This page ranks the largest institutional STOK shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
196
Total Reported Value
$2.18B
Largest Holder
Rtw Investments, Lp
Largest Position
$183.10M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
169
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Rtw Investments, Lp | 1.82% | 5,623,525 | $183,101,974 | $170,167,867 | -$12,934,108 | -7.06% | |
| Blackrock, Inc. | 0.00% | 5,385,714 | $175,358,848 | $162,971,706 | -$12,387,142 | -7.06% | |
| Fmr Llc | 0.01% | 5,383,666 | $175,292,165 | $162,909,733 | -$12,382,432 | -7.06% | |
| Lynx1 Capital Management Lp | 24.51% | 4,763,673 | $155,105,193 | $144,148,745 | -$10,956,448 | -7.06% | |
| Redmile Group, Llc | 8.98% | 4,164,120 | $135,583,747 | $126,006,271 | -$9,577,476 | -7.06% | |
| Morgan Stanley | 0.01% | 3,423,280 | $111,461,996 | $103,588,453 | -$7,873,543 | -7.06% | |
| Baker Bros. Advisors Lp | 0.62% | 3,336,697 | $108,642,854 | $100,968,451 | -$7,674,403 | -7.06% | |
| Toronto Dominion Bank | 0.20% | 3,173,258 | $103,321,280 | $96,022,787 | -$7,298,493 | -7.06% | |
| Wellington Management Group Llp | 0.02% | 3,095,700 | $100,795,992 | $93,675,882 | -$7,120,110 | -7.06% | |
| Bvf Inc/Il | 2.64% | 2,547,557 | $82,948,456 | $77,089,075 | -$5,859,381 | -7.06% | |
| Vanguard Capital Management Llc | 0.00% | 2,355,603 | $76,698,434 | $71,280,547 | -$5,417,887 | -7.06% | |
| State Street Corp | 0.00% | 2,276,512 | $74,123,231 | $68,887,253 | -$5,235,978 | -7.06% | |
| Siren, L.L.C. | 1.80% | 1,995,347 | $64,968,498 | $60,379,200 | -$4,589,298 | -7.06% | |
| Deerfield Management Company, L.P. | 0.70% | 1,823,500 | $59,373,160 | $55,179,110 | -$4,194,050 | -7.06% | |
| Geode Capital Management, Llc | 0.00% | 1,322,260 | $43,060,709 | $40,011,588 | -$3,049,121 | -7.08% | |
| Polar Capital Holdings Plc | 0.16% | 1,132,511 | $36,874,558 | $34,269,783 | -$2,604,775 | -7.06% | |
| Dimensional Fund Advisors Lp | 0.01% | 989,936 | $32,228,581 | $29,955,463 | -$2,273,118 | -7.05% | |
| Assenagon Asset Management S.A. | 0.05% | 907,015 | $29,532,408 | $27,446,274 | -$2,086,134 | -7.06% | |
| Goldman Sachs Group Inc | 0.00% | 830,702 | $27,047,658 | $25,137,043 | -$1,910,615 | -7.06% | |
| Mpm Bioimpact Llc | 1.93% | 767,038 | $24,974,757 | $23,210,570 | -$1,764,187 | -7.06% | |
| Opaleye Management Inc. | 3.00% | 700,000 | $22,792,000 | $21,182,000 | -$1,610,000 | -7.06% | |
| Troluce Capital Advisors Llc | 2.25% | 652,800 | $21,255,168 | $19,753,728 | -$1,501,440 | -7.06% | |
| Baillie Gifford & Co | 0.02% | 575,182 | $18,727,927 | $17,405,007 | -$1,322,920 | -7.06% | |
| Bank Of America Corp | 0.00% | 543,095 | $17,683,173 | $16,434,055 | -$1,249,118 | -7.06% | |
| Candriam S.C.A. | 0.08% | 502,020 | $16,345,771 | $15,191,125 | -$1,154,646 | -7.06% | |
| Tang Capital Management Llc | 0.83% | 500,000 | $16,280,000 | $15,130,000 | -$1,150,000 | -7.06% | |
| Millennium Management Llc | 0.01% | 472,141 | $15,372,911 | $14,286,987 | -$1,085,924 | -7.06% | |
| Vanguard Portfolio Management Llc | 0.00% | 462,682 | $15,064,926 | $14,000,757 | -$1,064,169 | -7.06% | |
| Charles Schwab Investment Management Inc | 0.00% | 437,175 | $14,234,418 | $13,228,916 | -$1,005,503 | -7.06% | |
| Erste Asset Management Gmbh | 0.13% | 446,000 | $14,169,420 | $13,495,960 | -$673,460 | -4.75% | |
| Northern Trust Corp | 0.00% | 431,630 | $14,053,872 | $13,061,124 | -$992,748 | -7.06% | |
| Vanguard Fiduciary Trust Co | 0.00% | 356,947 | $11,622,194 | $10,801,216 | -$820,978 | -7.06% | |
| Parkman Healthcare Partners Llc | 1.14% | 336,519 | $10,957,059 | $10,183,065 | -$773,994 | -7.06% | |
| Granahan Investment Management, Llc | 0.53% | 335,586 | $10,926,680 | $10,154,832 | -$771,848 | -7.06% | |
| Artisan Partners Limited Partnership | 0.02% | 315,492 | $10,272,420 | $9,546,788 | -$725,632 | -7.06% | |
| Birchview Capital, Lp | 3.89% | 210,000 | $6,837,600 | $6,354,600 | -$483,000 | -7.06% | |
| First Trust Advisors Lp | 0.00% | 163,459 | $5,322,225 | $4,946,269 | -$375,956 | -7.06% | |
| Ubs Group Ag | 0.00% | 158,304 | $5,154,378 | $4,790,279 | -$364,099 | -7.06% | |
| Invesco Ltd. | 0.00% | 150,045 | $4,885,466 | $4,540,362 | -$345,104 | -7.06% | |
| Bank Of New York Mellon Corp | 0.00% | 143,407 | $4,669,332 | $4,339,496 | -$329,836 | -7.06% | |
| Franklin Resources Inc | 0.00% | 142,793 | $4,649,340 | $4,320,916 | -$328,424 | -7.06% | |
| Dafna Capital Management Llc | 0.97% | 130,875 | $4,261,290 | $3,960,278 | -$301,013 | -7.06% | |
| Citadel Advisors Llc | 0.00% | 123,022 | $4,005,596 | $3,722,646 | -$282,950 | -7.06% | |
| Susquehanna Portfolio Strategies, Llc | 0.06% | 119,226 | $3,881,999 | $3,607,779 | -$274,220 | -7.06% | |
| Gilder Gagnon Howe & Co Llc | 0.04% | 112,627 | $3,667,135 | $3,408,093 | -$259,042 | -7.06% | |
| Nuveen, Llc | 0.00% | 108,617 | $3,536,570 | $3,286,750 | -$249,820 | -7.06% | |
| Ecor1 Capital, Llc | 0.14% | 100,000 | $3,256,000 | $3,026,000 | -$230,000 | -7.06% | |
| Palo Alto Investors Lp | 0.42% | 84,631 | $2,755,585 | $2,560,934 | -$194,651 | -7.06% | |
| Hussman Strategic Advisors, Inc. | 0.59% | 84,000 | $2,735,040 | $2,541,840 | -$193,200 | -7.06% | |
| Rhenman & Partners Asset Management Ab | 0.33% | 83,000 | $2,702,480 | $2,511,580 | -$190,900 | -7.06% |
Frequently asked questions about STOK
Who owns the most STOK stock?
The largest holders of STOK are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for STOKE THERAPEUTICS INC (STOK).
Is STOK widely held by superinvestors?
Many widely followed stocks like STOK appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly STOK is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.