VYNE THERAPEUTICS INC (VYNE) Top Institutional Shareholders
VYNE THERAPEUTICS INC (VYNE) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $7.60M in VYNE holdings during the latest filing period.
Nantahala Capital Management, Llc is currently the largest disclosed institutional shareholder of VYNE tracked by InsiderSet, reporting ownership valued at approximately $1.20M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $1.26M, representing an estimated gain of +5.62% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 85% of the total disclosed VYNE value among the investors covered in this analysis. Major shareholders include Nantahala Capital Management, Llc, Lynx1 Capital Management Lp, Shay Capital Llc, and several other long-term asset managers with concentrated positions in VYNE THERAPEUTICS INC (VYNE).
This page ranks the largest institutional VYNE shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
41
Total Reported Value
$7.60M
Largest Holder
Nantahala Capital Management, Llc
Largest Position
$1.20M
Insider Transactions (90d)
0
Latest Filing Quarter
Q1 2026
New Institutional Positions
48
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, Llc | 0.07% | 2,000,000 | $1,195,000 | $1,262,200 | +$67,200 | +5.62% | |
| Lynx1 Capital Management Lp | 0.15% | 1,628,700 | $973,148 | $1,027,873 | +$54,725 | +5.62% | |
| Shay Capital Llc | 0.14% | 1,610,242 | $962,120 | $1,016,224 | +$54,104 | +5.62% | |
| Anson Funds Management Lp | 0.10% | 1,243,106 | $742,756 | $784,524 | +$41,768 | +5.62% | |
| Adar1 Capital Management, Llc | 0.04% | 1,063,899 | $635,680 | $671,427 | +$35,747 | +5.62% | |
| T3 Companies, Llc | 0.77% | 945,000 | $564,638 | $596,390 | +$31,752 | +5.62% | |
| Braidwell Lp | 0.02% | 916,077 | $547,356 | $578,136 | +$30,780 | +5.62% | |
| Citadel Advisors Llc | 0.00% | 514,443 | $307,380 | $324,665 | +$17,285 | +5.62% | |
| Kvp Capital Advisors, Lp | 0.22% | 500,551 | $299,079 | $315,898 | +$16,819 | +5.62% | |
| Two Sigma Investments, Lp | 0.00% | 426,412 | $254,781 | $269,109 | +$14,328 | +5.62% | |
| Geode Capital Management, Llc | 0.00% | 322,711 | $192,824 | $203,663 | +$10,839 | +5.62% | |
| Ikarian Capital, Llc | 0.02% | 264,912 | $158,284 | $167,186 | +$8,902 | +5.62% | |
| Vanguard Capital Management Llc | 0.00% | 264,557 | $158,205 | $166,962 | +$8,757 | +5.54% | |
| Vanguard Fiduciary Trust Co | 0.00% | 183,443 | $109,699 | $115,771 | +$6,072 | +5.54% | |
| Ubs Group Ag | 0.00% | 179,784 | $107,511 | $113,462 | +$5,951 | +5.53% | |
| Xtx Topco Ltd | 0.00% | 158,396 | $94,642 | $99,964 | +$5,322 | +5.62% | |
| Rangeley Capital, Llc | 0.08% | 118,064 | $70,543 | $74,510 | +$3,967 | +5.62% | |
| Jane Street Group, Llc | 0.00% | 95,645 | $57,148 | $60,362 | +$3,214 | +5.62% | |
| Boothbay Fund Management, Llc | 0.00% | 81,371 | $48,619 | $51,353 | +$2,734 | +5.62% | |
| Susquehanna International Group, Llp | 0.00% | 57,784 | $34,526 | $36,467 | +$1,941 | +5.62% | |
| Blackrock, Inc. | 0.00% | 44,405 | $26,532 | $28,024 | +$1,492 | +5.62% | |
| Northern Trust Corp | 0.00% | 23,110 | $13,808 | $14,585 | +$777 | +5.63% | |
| Commonwealth Equity Services, Llc | 0.00% | 18,298 | $10,930 | $11,548 | +$618 | +5.65% | |
| Renaissance Technologies LLC | Jim Simons | 0.00% | 17,300 | $10,337 | $10,918 | +$581 | +5.62% |
| State Street Corp | 0.00% | 15,765 | $9,420 | $9,949 | +$529 | +5.62% | |
| Harvest Investment Services, Llc | 0.00% | 11,059 | $6,608 | $6,979 | +$371 | +5.62% | |
| Tower Research Capital Llc (Trc) | 0.00% | 3,527 | $2,107 | $2,226 | +$119 | +5.64% | |
| Acorn Capital Advisors, Llc | 0.00% | 1,425 | $855 | $899 | +$44 | +5.18% | |
| Mb, Levis & Associates, Llc | 0.00% | 1,041 | $622 | $657 | +$35 | +5.62% | |
| Vanguard Global Advisers, Llc | 0.00% | 1,004 | $600 | $634 | +$34 | +5.60% | |
| Northwestern Mutual Wealth Management Co | 0.00% | 800 | $478 | $505 | +$27 | +5.62% | |
| Hurley Capital, Llc | 0.00% | 561 | $335 | $354 | +$19 | +5.69% | |
| Cwm, Llc | 0.00% | 500 | $299 | $316 | +$17 | +5.54% | |
| Acadian Asset Management Llc | 0.00% | 381,797 | $228 | $240,952 | +$240,724 | +105580.74% | |
| Wells Fargo & Company/Mn | 0.00% | 65 | $39 | $41 | +$2 | +5.18% | |
| Morgan Stanley | 0.00% | 43 | $26 | $27 | +$1 | +4.37% | |
| Fny Investment Advisers, Llc | 0.01% | 35,000 | $20 | $22,089 | +$22,069 | +110342.50% | |
| Hrt Financial Lp | 0.00% | 27,569 | $16 | $17,399 | +$17,383 | +108642.47% | |
| Truvestments Capital Llc | 0.00% | 25 | $15 | $16 | +$1 | +5.18% | |
| Nfsg Corp | 0.00% | 10 | $6 | $6 | +$0 | +5.18% | |
| Larson Financial Group Llc | 0.00% | 2 | $1 | $1 | +$0 | +26.22% |
Frequently asked questions about VYNE
Who owns the most VYNE stock?
The largest holders of VYNE are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for VYNE THERAPEUTICS INC (VYNE).
Is VYNE widely held by superinvestors?
Many widely followed stocks like VYNE appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly VYNE is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.