ZYMEWORKS INC (ZYME) Institutional Ownership Changes & 13F Activity

ZYMEWORKS INC (ZYME). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Nomura Asset Management International Inc., Perceptive Advisors Llc, Assenagon Asset Management S.A., Citadel Advisors Llc, and Jane Street Group, Llc.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Envestnet Asset Management IncBuy+8,256+20.4%48,675$1.27MQ2 2026Sep 23, 2026
State Street CorpBuy+76,439+7.6%1,088,216$28.45MQ2 2026Sep 22, 2026
Manufacturers Life Insurance Company, TheSell-706-2.2%30,886$807.36KQ2 2026Sep 09, 2026
Citadel Advisors LlcSell-235,882-20.5%914,136$23.90MQ2 2026Sep 02, 2026
California State Teachers Retirement SystemBuy+355+0.9%37,744$986.63KQ2 2026Aug 24, 2026
Assenagon Asset Management S.A.Buy+524,041+72.0%1,252,027$32.73MQ2 2026Aug 21, 2026
Nomura Asset Management International Inc.Buy+889,802—889,802$23.26MQ2 2026Aug 14, 2026
Perceptive Advisors LlcBuy+672,875+19.2%4,182,953$109.34MQ2 2026Aug 14, 2026
Jane Street Group, LlcSell-209,530-92.3%17,437$455.80KQ2 2026Aug 14, 2026
Prosight Management, LpBuy+135,385+25.1%674,434$17.63MQ2 2026Aug 14, 2026
Goldman Sachs Group IncSell-128,664-21.5%470,822$12.31MQ2 2026Aug 14, 2026
Invesco Ltd.Buy+112,212—112,212$2.93MQ2 2026Aug 14, 2026
Summittx Capital, L.P.Sell-110,625-34.4%210,802$5.51MQ2 2026Aug 14, 2026
D. E. Shaw & Co., Inc.Sell-90,814-38.5%144,807$3.79MQ2 2026Aug 14, 2026
State Of Wisconsin Investment BoardBuy+89,473+135.3%155,579$4.07MQ2 2026Aug 14, 2026
Granahan Investment Management, LlcBuy+85,384+34.0%336,157$8.79MQ2 2026Aug 14, 2026
Bvf Inc/IlSell-85,000-2.3%3,649,142$95.39MQ2 2026Aug 14, 2026
Lmr Partners LlpBuy+82,500—82,500$2.16MQ2 2026Aug 14, 2026
Ameriprise Financial IncBuy+82,264—82,264$2.15MQ2 2026Aug 14, 2026
Qube Research & Technologies LtdBuy+81,653+15.9%593,590$15.52MQ2 2026Aug 14, 2026
Two Sigma Investments, LpBuy+71,874—71,874$1.88MQ2 2026Aug 14, 2026
Squarepoint Ops LlcSell-66,946-80.5%16,200$423.47KQ2 2026Aug 14, 2026
Silvercrest Asset Management Group LlcBuy+60,117+36.7%223,766$5.85MQ2 2026Aug 14, 2026
Manatuck Hill Partners, LlcBuy+60,000+150.0%100,000$2.61MQ2 2026Aug 14, 2026
Susquehanna Portfolio Strategies, LlcSell-34,547-34.6%65,248$1.71MQ2 2026Aug 14, 2026
Charles Schwab Investment Management IncSell-32,708-17.7%152,416$3.98MQ2 2026Aug 14, 2026
Wellington Management Group LlpSell-28,676-20.7%110,014$2.88MQ2 2026Aug 14, 2026
Wells Fargo & Company/MnBuy+27,563+14.5%217,199$5.68MQ2 2026Aug 14, 2026
Brevan Howard Capital Management LpBuy+25,956—25,956$678.49KQ2 2026Aug 14, 2026
Hsbc Holdings PlcSell-22,189-58.7%15,588$421.20KQ2 2026Aug 14, 2026
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Frequently asked questions about ZYME activity

  • Which institutional owners are buying ZYME?

    Institutional owners buying ZYME include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in ZYME activity?

    "Buy" means an investor increased their reported position in ZYME compared to the prior reporting period. This reflects growing exposure to ZYMEWORKS INC (ZYME) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in ZYME increasing?

    Institutional interest in ZYME can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.