ZYMEWORKS INC (ZYME) Institutional Ownership Changes & 13F Activity
ZYMEWORKS INC (ZYME). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Nomura Asset Management International Inc., Perceptive Advisors Llc, Assenagon Asset Management S.A., Citadel Advisors Llc, and Jane Street Group, Llc.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Envestnet Asset Management Inc | Buy | +8,256 | +20.4% | 48,675 | $1.27M | Q2 2026 | Sep 23, 2026 |
| State Street Corp | Buy | +76,439 | +7.6% | 1,088,216 | $28.45M | Q2 2026 | Sep 22, 2026 |
| Manufacturers Life Insurance Company, The | Sell | -706 | -2.2% | 30,886 | $807.36K | Q2 2026 | Sep 09, 2026 |
| Citadel Advisors Llc | Sell | -235,882 | -20.5% | 914,136 | $23.90M | Q2 2026 | Sep 02, 2026 |
| California State Teachers Retirement System | Buy | +355 | +0.9% | 37,744 | $986.63K | Q2 2026 | Aug 24, 2026 |
| Assenagon Asset Management S.A. | Buy | +524,041 | +72.0% | 1,252,027 | $32.73M | Q2 2026 | Aug 21, 2026 |
| Nomura Asset Management International Inc. | Buy | +889,802 | — | 889,802 | $23.26M | Q2 2026 | Aug 14, 2026 |
| Perceptive Advisors Llc | Buy | +672,875 | +19.2% | 4,182,953 | $109.34M | Q2 2026 | Aug 14, 2026 |
| Jane Street Group, Llc | Sell | -209,530 | -92.3% | 17,437 | $455.80K | Q2 2026 | Aug 14, 2026 |
| Prosight Management, Lp | Buy | +135,385 | +25.1% | 674,434 | $17.63M | Q2 2026 | Aug 14, 2026 |
| Goldman Sachs Group Inc | Sell | -128,664 | -21.5% | 470,822 | $12.31M | Q2 2026 | Aug 14, 2026 |
| Invesco Ltd. | Buy | +112,212 | — | 112,212 | $2.93M | Q2 2026 | Aug 14, 2026 |
| Summittx Capital, L.P. | Sell | -110,625 | -34.4% | 210,802 | $5.51M | Q2 2026 | Aug 14, 2026 |
| D. E. Shaw & Co., Inc. | Sell | -90,814 | -38.5% | 144,807 | $3.79M | Q2 2026 | Aug 14, 2026 |
| State Of Wisconsin Investment Board | Buy | +89,473 | +135.3% | 155,579 | $4.07M | Q2 2026 | Aug 14, 2026 |
| Granahan Investment Management, Llc | Buy | +85,384 | +34.0% | 336,157 | $8.79M | Q2 2026 | Aug 14, 2026 |
| Bvf Inc/Il | Sell | -85,000 | -2.3% | 3,649,142 | $95.39M | Q2 2026 | Aug 14, 2026 |
| Lmr Partners Llp | Buy | +82,500 | — | 82,500 | $2.16M | Q2 2026 | Aug 14, 2026 |
| Ameriprise Financial Inc | Buy | +82,264 | — | 82,264 | $2.15M | Q2 2026 | Aug 14, 2026 |
| Qube Research & Technologies Ltd | Buy | +81,653 | +15.9% | 593,590 | $15.52M | Q2 2026 | Aug 14, 2026 |
| Two Sigma Investments, Lp | Buy | +71,874 | — | 71,874 | $1.88M | Q2 2026 | Aug 14, 2026 |
| Squarepoint Ops Llc | Sell | -66,946 | -80.5% | 16,200 | $423.47K | Q2 2026 | Aug 14, 2026 |
| Silvercrest Asset Management Group Llc | Buy | +60,117 | +36.7% | 223,766 | $5.85M | Q2 2026 | Aug 14, 2026 |
| Manatuck Hill Partners, Llc | Buy | +60,000 | +150.0% | 100,000 | $2.61M | Q2 2026 | Aug 14, 2026 |
| Susquehanna Portfolio Strategies, Llc | Sell | -34,547 | -34.6% | 65,248 | $1.71M | Q2 2026 | Aug 14, 2026 |
| Charles Schwab Investment Management Inc | Sell | -32,708 | -17.7% | 152,416 | $3.98M | Q2 2026 | Aug 14, 2026 |
| Wellington Management Group Llp | Sell | -28,676 | -20.7% | 110,014 | $2.88M | Q2 2026 | Aug 14, 2026 |
| Wells Fargo & Company/Mn | Buy | +27,563 | +14.5% | 217,199 | $5.68M | Q2 2026 | Aug 14, 2026 |
| Brevan Howard Capital Management Lp | Buy | +25,956 | — | 25,956 | $678.49K | Q2 2026 | Aug 14, 2026 |
| Hsbc Holdings Plc | Sell | -22,189 | -58.7% | 15,588 | $421.20K | Q2 2026 | Aug 14, 2026 |
Frequently asked questions about ZYME activity
Which institutional owners are buying ZYME?
Institutional owners buying ZYME include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in ZYME activity?
"Buy" means an investor increased their reported position in ZYME compared to the prior reporting period. This reflects growing exposure to ZYMEWORKS INC (ZYME) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in ZYME increasing?
Institutional interest in ZYME can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
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