TANGO THERAPEUTICS INC (TNGX) Institutional Shareholders
TANGO THERAPEUTICS INC (TNGX) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026. The institutional investors covered on this page collectively reported approximately $6.17B in TNGX holdings during the latest filing period.
Rtw Investments, Lp is currently the largest disclosed institutional shareholder of TNGX tracked by InsiderSet, reporting ownership valued at approximately $434.53M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $340.70M, representing an estimated loss of -21.59% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 50% of the total disclosed TNGX value among the investors covered in this analysis. Major shareholders include Rtw Investments, Lp, Blackrock, Inc., Fmr Llc, and several other long-term asset managers with concentrated positions in TANGO THERAPEUTICS INC (TNGX).
This page ranks the largest institutional TNGX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
239
Total Reported Value
$6.17B
Largest Holder
Rtw Investments, Lp
Largest Position
$434.53M
Insider Transactions (90d)
14
Latest Filing Quarter
Q2 2026
New Institutional Positions
98
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Rtw Investments, Lp | 3.71% | 13,900,620 | $434,533,381 | $340,704,196 | -$93,829,185 | -21.59% | |
| Blackrock, Inc. | 0.01% | 12,438,444 | $388,825,760 | $304,866,262 | -$83,959,498 | -21.59% | |
| Fmr Llc | 0.02% | 12,333,339 | $385,540,161 | $302,290,139 | -$83,250,022 | -21.59% | |
| Farallon Capital Management Llc | 2.25% | 12,277,000 | $383,779,020 | $300,909,270 | -$82,869,750 | -21.59% | |
| Boxer Capital Management, Llc | 25.61% | 10,876,219 | $339,990,606 | $266,576,128 | -$73,414,478 | -21.59% | |
| Goldman Sachs Group Inc | 0.03% | 9,980,620 | $311,994,191 | $244,624,996 | -$67,369,195 | -21.59% | |
| Tcg Crossover Management, Llc | 6.82% | 9,081,201 | $283,878,343 | $222,580,237 | -$61,298,106 | -21.59% | |
| Paradigm Biocapital Advisors Lp | 3.72% | 6,357,523 | $198,736,169 | $155,822,889 | -$42,913,280 | -21.59% | |
| Siren, L.L.C. | 3.92% | 6,179,364 | $193,166,919 | $151,456,212 | -$41,710,707 | -21.59% | |
| State Street Corp | 0.01% | 5,979,806 | $186,928,736 | $146,565,045 | -$40,363,691 | -21.59% | |
| Vanguard Capital Management Llc | 0.00% | 5,957,348 | $186,226,699 | $146,014,599 | -$40,212,100 | -21.59% | |
| Adage Capital Partners Gp, L.L.C. | 0.25% | 5,600,000 | $175,056,000 | $137,256,000 | -$37,800,000 | -21.59% | |
| Deep Track Capital, Lp | 1.93% | 4,200,000 | $131,292,000 | $102,942,000 | -$28,350,000 | -21.59% | |
| Deerfield Management Company, L.P. | 1.37% | 4,190,611 | $130,998,500 | $102,711,876 | -$28,286,624 | -21.59% | |
| Woodline Partners Lp | 0.39% | 4,000,567 | $125,057,724 | $98,053,897 | -$27,003,827 | -21.59% | |
| Trv Gp Iv, Llc | 47.37% | 6,374,574 | $120,181,383 | $156,240,809 | +$36,059,426 | +30.00% | |
| Geode Capital Management, Llc | 0.01% | 3,742,791 | $117,021,411 | $91,735,807 | -$25,285,604 | -21.61% | |
| Perceptive Advisors Llc | 1.64% | 3,377,000 | $105,565,020 | $82,770,270 | -$22,794,750 | -21.59% | |
| Seven Fleet Capital Management Lp | 15.79% | 3,228,144 | $95,660,985 | $79,121,809 | -$16,539,176 | -17.29% | |
| Logos Global Management Lp | 3.84% | 2,850,000 | $89,091,000 | $69,853,500 | -$19,237,500 | -21.59% | |
| Caligan Partners Lp | 3.77% | 2,500,103 | $78,153,220 | $61,277,525 | -$16,875,695 | -21.59% | |
| Holocene Advisors, Lp | 0.17% | 2,410,939 | $75,365,953 | $59,092,115 | -$16,273,838 | -21.59% | |
| Commodore Capital Lp | 4.19% | 2,250,000 | $70,335,000 | $55,147,500 | -$15,187,500 | -21.59% | |
| Balyasny Asset Management L.P. | 0.12% | 2,016,379 | $63,032,008 | $49,421,449 | -$13,610,559 | -21.59% | |
| Jefferies Financial Group Inc. | 0.58% | 2,010,534 | $62,849,293 | $49,278,188 | -$13,571,105 | -21.59% | |
| Candriam S.C.A. | 0.23% | 1,630,553 | $50,922,046 | $39,964,854 | -$10,957,192 | -21.52% | |
| Janus Henderson Group Plc | 0.02% | 2,394,972 | $50,066,890 | $58,700,764 | +$8,633,874 | +17.24% | |
| Vanguard Portfolio Management Llc | 0.00% | 1,585,111 | $49,550,570 | $38,851,071 | -$10,699,499 | -21.59% | |
| Jpmorgan Chase & Co | 0.00% | 1,418,193 | $46,318,195 | $34,759,910 | -$11,558,285 | -24.95% | |
| Polar Capital Holdings Plc | 0.13% | 1,480,740 | $46,287,932 | $36,292,937 | -$9,994,995 | -21.59% | |
| Vivo Capital, Llc | 3.94% | 1,379,769 | $43,131,579 | $33,818,138 | -$9,313,441 | -21.59% | |
| Cormorant Asset Management, Lp | 2.08% | 1,300,000 | $40,638,000 | $31,863,000 | -$8,775,000 | -21.59% | |
| Northern Trust Corp | 0.00% | 1,231,933 | $38,510,226 | $30,194,678 | -$8,315,548 | -21.59% | |
| Stempoint Capital Lp | 6.62% | 1,223,019 | $38,231,574 | $29,976,196 | -$8,255,378 | -21.59% | |
| Federated Hermes, Inc. | 0.05% | 1,214,613 | $37,968,802 | $29,770,165 | -$8,198,637 | -21.59% | |
| Voya Investment Management Llc | 0.03% | 1,103,030 | $34,480,718 | $27,035,265 | -$7,445,453 | -21.59% | |
| Charles Schwab Investment Management Inc | 0.00% | 1,072,059 | $33,512,564 | $26,276,166 | -$7,236,398 | -21.59% | |
| Sixth Street Partners Management Company, L.P. | 0.00% | 1,072,059 | $33,512,564 | $26,276,166 | -$7,236,398 | -21.59% | |
| American Century Companies Inc | 0.01% | 1,013,794 | $31,691,245 | $24,848,091 | -$6,843,154 | -21.59% | |
| Integral Health Asset Management, Llc | 1.28% | 1,000,000 | $31,260,000 | $24,510,000 | -$6,750,000 | -21.59% | |
| Vanguard Fiduciary Trust Co | 0.01% | 915,565 | $28,620,562 | $22,440,498 | -$6,180,064 | -21.59% | |
| Nuveen, Llc | 0.01% | 890,170 | $27,826,714 | $21,818,067 | -$6,008,647 | -21.59% | |
| Samlyn Capital, Llc | 0.40% | 766,473 | $23,959,946 | $18,786,253 | -$5,173,693 | -21.59% | |
| Renaissance Technologies LLC | Jim Simons | 0.03% | 748,300 | $23,391,858 | $18,340,833 | -$5,051,025 | -21.59% |
| Soleus Capital Management, L.P. | 0.76% | 709,000 | $22,163,340 | $17,377,590 | -$4,785,750 | -21.59% | |
| Arrowmark Colorado Holdings Llc | 0.92% | 708,385 | $22,144,115 | $17,362,516 | -$4,781,599 | -21.59% | |
| Bellevue Group Ag | 0.46% | 694,182 | $21,700,129 | $17,014,401 | -$4,685,728 | -21.59% | |
| Alyeska Investment Group, L.P. | 0.06% | 691,109 | $21,604,067 | $16,939,082 | -$4,664,985 | -21.59% | |
| Connor, Clark & Lunn Investment Management Ltd. | 0.04% | 636,070 | $19,883,549 | $15,590,076 | -$4,293,473 | -21.59% | |
| Bank Of America Corp | 0.00% | 600,834 | $18,782,070 | $14,726,441 | -$4,055,629 | -21.59% |
Frequently asked questions about TNGX
Who owns the most TNGX stock?
The largest holders of TNGX are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for TANGO THERAPEUTICS INC (TNGX).
Is TNGX widely held by superinvestors?
Many widely followed stocks like TNGX appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly TNGX is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.