DESIGN THERAPEUTICS INC (DSGN) Institutional Ownership Changes & 13F Activity
DESIGN THERAPEUTICS INC (DSGN). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Frazier Life Sciences Management, L.P., Trails Edge Capital Partners, Lp, Logos Global Management Lp, Caption Management, Llc, and Driehaus Capital Management Llc.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Citadel Advisors Llc | Sell | -149,542 | -64.6% | 81,971 | $1.19M | Q2 2026 | Sep 02, 2026 |
| California State Teachers Retirement System | Sell | -957 | -74.1% | 335 | $4.85K | Q2 2026 | Aug 24, 2026 |
| Almitas Capital Llc | Sell | -503,442 | -32.9% | 1,026,893 | $14.86M | Q2 2026 | Aug 17, 2026 |
| Public Employees Retirement System Of Ohio | Buy | +5,507 | +36.2% | 20,700 | $299.53K | Q2 2026 | Aug 17, 2026 |
| Frazier Life Sciences Management, L.P. | Buy | +1,809,854 | — | 1,809,854 | $26.19M | Q2 2026 | Aug 14, 2026 |
| Trails Edge Capital Partners, Lp | Buy | +1,149,269 | +134.9% | 2,001,282 | $28.96M | Q2 2026 | Aug 14, 2026 |
| Logos Global Management Lp | Buy | +1,050,000 | +53.8% | 3,000,000 | $43.41M | Q2 2026 | Aug 14, 2026 |
| Caption Management, Llc | Buy | +1,031,390 | +1189.5% | 1,118,098 | $16.18M | Q2 2026 | Aug 14, 2026 |
| Driehaus Capital Management Llc | Buy | +916,128 | +52.5% | 2,661,115 | $38.51M | Q2 2026 | Aug 14, 2026 |
| Sofinnova Investments, Inc. | Buy | +865,135 | — | 865,135 | $12.52M | Q2 2026 | Aug 14, 2026 |
| Qube Research & Technologies Ltd | Buy | +402,896 | +1178.6% | 437,079 | $6.32M | Q2 2026 | Aug 14, 2026 |
| Point72 Asset Management, L.P. | Sell | -356,301 | -13.1% | 2,366,453 | $34.24M | Q2 2026 | Aug 14, 2026 |
| Jacobs Levy Equity Management, Inc | Buy | +276,212 | +95.4% | 565,597 | $8.18M | Q2 2026 | Aug 14, 2026 |
| D. E. Shaw & Co., Inc. | Sell | -274,625 | -58.4% | 195,645 | $2.83M | Q2 2026 | Aug 14, 2026 |
| Woodline Partners Lp | Sell | -261,147 | -27.2% | 700,354 | $10.13M | Q2 2026 | Aug 14, 2026 |
| Eversept Partners, Lp | Buy | +190,000 | — | 190,000 | $2.75M | Q2 2026 | Aug 14, 2026 |
| J. Goldman & Co Lp | Buy | +176,770 | — | 176,770 | $2.56M | Q2 2026 | Aug 14, 2026 |
| Goldman Sachs Group Inc | Buy | +151,866 | +30.1% | 656,584 | $9.50M | Q2 2026 | Aug 14, 2026 |
| Acuta Capital Partners, Llc | Buy | +136,664 | +93.7% | 282,564 | $4.09M | Q2 2026 | Aug 14, 2026 |
| Kennedy Capital Management Llc | Buy | +112,482 | +41.4% | 384,036 | $5.56M | Q2 2026 | Aug 14, 2026 |
| Balyasny Asset Management L.P. | Buy | +111,103 | — | 111,103 | $1.61M | Q2 2026 | Aug 14, 2026 |
| Sei Investments Co | Sell | -110,463 | -82.9% | 22,740 | $329.05K | Q2 2026 | Aug 14, 2026 |
| Dafna Capital Management Llc | Buy | +102,600 | — | 102,600 | $1.48M | Q2 2026 | Aug 14, 2026 |
| Elmind Capital, Lp | Sell | -100,000 | -48.1% | 107,900 | $1.56M | Q2 2026 | Aug 14, 2026 |
| Baker Bros. Advisors Lp | Buy | +92,452 | +3.6% | 2,678,430 | $38.76M | Q2 2026 | Aug 14, 2026 |
| Trexquant Investment Lp | Sell | -88,961 | -76.0% | 28,150 | $407.33K | Q2 2026 | Aug 14, 2026 |
| Summittx Capital, L.P. | Buy | +80,663 | — | 80,663 | $1.17M | Q2 2026 | Aug 14, 2026 |
| Ameriprise Financial Inc | Buy | +67,598 | — | 67,598 | $978.14K | Q2 2026 | Aug 14, 2026 |
| Squarepoint Ops Llc | Sell | -56,487 | -65.6% | 29,630 | $428.75K | Q2 2026 | Aug 14, 2026 |
| Aqr Capital Management Llc | Buy | +45,161 | +174.0% | 71,114 | $1.03M | Q2 2026 | Aug 14, 2026 |
Frequently asked questions about DSGN activity
Which institutional owners are buying DSGN?
Institutional owners buying DSGN include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in DSGN activity?
"Buy" means an investor increased their reported position in DSGN compared to the prior reporting period. This reflects growing exposure to DESIGN THERAPEUTICS INC (DSGN) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in DSGN increasing?
Institutional interest in DSGN can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related DSGN Institutional Insights
- DSGN Overview
- DSGN 13F Institutional Holders
- DSGN Top Institutional Shareholders
- Healthcare Sector Institutional Ownership
- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
- Most Bought Healthcare Stocks By Institutional Investors
- Most Sold Healthcare Stocks By Institutional Investors
- DSGN Insider Trading & SEC Form 4 Activity
- DSGN Articles
- Top Institutional Investor Stock Rankings