TAYSHA GENE THERAPIES INC (TSHA) Institutional Ownership Changes & 13F Activity
TAYSHA GENE THERAPIES INC (TSHA). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Mpm Bioimpact Llc, Wellington Management Group Llp, Farallon Capital Management Llc, Avoro Capital Advisors Llc, and Orbimed Advisors Llc.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Manufacturers Life Insurance Company, The | Buy | +4,724 | +4.8% | 104,095 | $708.89K | Q2 2026 | Sep 09, 2026 |
| Citadel Advisors Llc | Buy | +1,124,152 | +273.4% | 1,535,287 | $10.46M | Q2 2026 | Sep 02, 2026 |
| California State Teachers Retirement System | Buy | +32,441 | +23.7% | 169,374 | $1.15M | Q2 2026 | Aug 24, 2026 |
| Seven Fleet Capital Management Lp | Buy | +878,692 | +140.4% | 1,504,400 | $9.94M | Q2 2026 | Aug 17, 2026 |
| Jefferies Financial Group Inc. | Sell | -150,200 | -31.4% | 328,800 | $2.24M | Q2 2026 | Aug 17, 2026 |
| Mpm Bioimpact Llc | Buy | +4,500,000 | — | 4,500,000 | $30.64M | Q2 2026 | Aug 14, 2026 |
| Wellington Management Group Llp | Buy | +3,349,244 | +534.7% | 3,975,605 | $27.07M | Q2 2026 | Aug 14, 2026 |
| Farallon Capital Management Llc | Buy | +2,250,000 | — | 2,250,000 | $15.32M | Q2 2026 | Aug 14, 2026 |
| Avoro Capital Advisors Llc | Buy | +2,188,888 | +10.1% | 23,888,888 | $162.68M | Q2 2026 | Aug 14, 2026 |
| Orbimed Advisors Llc | Buy | +2,000,000 | — | 2,000,000 | $13.62M | Q2 2026 | Aug 14, 2026 |
| Heights Capital Management, Inc | Buy | +1,500,000 | — | 1,500,000 | $10.21M | Q2 2026 | Aug 14, 2026 |
| Vestal Point Capital, Lp | Buy | +1,415,000 | +7.9% | 19,415,000 | $132.22M | Q2 2026 | Aug 14, 2026 |
| Barclays Plc | Sell | -1,181,351 | -42.0% | 1,630,659 | $11.10M | Q2 2026 | Aug 14, 2026 |
| Millennium Management Llc | Sell | -1,154,982 | -35.2% | 2,126,838 | $14.48M | Q2 2026 | Aug 14, 2026 |
| Octagon Capital Advisors Lp | Buy | +833,333 | +9.4% | 9,693,244 | $66.01M | Q2 2026 | Aug 14, 2026 |
| Adage Capital Partners Gp, L.L.C. | Buy | +553,000 | — | 553,000 | $3.77M | Q2 2026 | Aug 14, 2026 |
| Polar Capital Holdings Plc | Sell | -537,207 | -9.5% | 5,117,133 | $34.85M | Q2 2026 | Aug 14, 2026 |
| Diadema Partners Lp | Buy | +522,619 | — | 522,619 | $3.56M | Q2 2026 | Aug 14, 2026 |
| Holocene Advisors, Lp | Buy | +510,000 | — | 510,000 | $3.47M | Q2 2026 | Aug 14, 2026 |
| Two Sigma Investments, Lp | Sell | -507,365 | -68.4% | 234,716 | $1.60M | Q2 2026 | Aug 14, 2026 |
| Ghisallo Capital Management Llc | Buy | +505,000 | — | 505,000 | $3.44M | Q2 2026 | Aug 14, 2026 |
| Burkehill Global Management, Lp | Buy | +500,000 | — | 500,000 | $3.40M | Q2 2026 | Aug 14, 2026 |
| Granahan Investment Management, Llc | Buy | +421,936 | +47.8% | 1,305,177 | $8.89M | Q2 2026 | Aug 14, 2026 |
| Charles Schwab Investment Management Inc | Buy | +392,096 | +21.7% | 2,200,695 | $14.99M | Q2 2026 | Aug 14, 2026 |
| Trexquant Investment Lp | Buy | +379,577 | — | 379,577 | $2.58M | Q2 2026 | Aug 14, 2026 |
| Goldman Sachs Group Inc | Buy | +343,473 | +1.5% | 22,713,118 | $154.68M | Q2 2026 | Aug 14, 2026 |
| Bank Of America Corp | Sell | -304,201 | -18.1% | 1,372,845 | $9.35M | Q2 2026 | Aug 14, 2026 |
| Invesco Ltd. | Buy | +264,379 | — | 264,379 | $1.80M | Q2 2026 | Aug 14, 2026 |
| Qube Research & Technologies Ltd | Buy | +259,605 | — | 259,605 | $1.77M | Q2 2026 | Aug 14, 2026 |
| Sphera Funds Management Ltd. | Buy | +250,000 | — | 250,000 | $1.70M | Q2 2026 | Aug 14, 2026 |
Frequently asked questions about TSHA activity
Which institutional owners are buying TSHA?
Institutional owners buying TSHA include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in TSHA activity?
"Buy" means an investor increased their reported position in TSHA compared to the prior reporting period. This reflects growing exposure to TAYSHA GENE THERAPIES INC (TSHA) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in TSHA increasing?
Institutional interest in TSHA can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related TSHA Institutional Insights
- TSHA Overview
- TSHA 13F Institutional Holders
- TSHA Top Institutional Shareholders
- Healthcare Sector Institutional Ownership
- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
- Most Bought Healthcare Stocks By Institutional Investors
- Most Sold Healthcare Stocks By Institutional Investors
- TSHA Insider Trading & SEC Form 4 Activity
- TSHA Articles
- Top Institutional Investor Stock Rankings