TAYSHA GENE THERAPIES INC (TSHA) Institutional Shareholders
TAYSHA GENE THERAPIES INC (TSHA) is currently reported in institutional portfolios tracked by InsiderSet based on the latest available SEC Form 13F filings for the quarter ended March 31, 2026. The institutional investors covered on this page collectively reported approximately $1.20B in TSHA holdings during the latest filing period.
Ra Capital Management, L.P. is currently the largest disclosed institutional shareholder of TSHA tracked by InsiderSet, reporting ownership valued at approximately $105.29M in its March 31, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $138.04M, representing an estimated gain of +31.10% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 64% of the total disclosed TSHA value among the investors covered in this analysis. Major shareholders include Ra Capital Management, L.P., Goldman Sachs Group Inc, Avoro Capital Advisors Llc, and several other long-term asset managers with concentrated positions in TAYSHA GENE THERAPIES INC (TSHA).
This page ranks the largest institutional TSHA shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
185
Total Reported Value
$1.20B
Largest Holder
Ra Capital Management, L.P.
Largest Position
$105.29M
Insider Transactions (90d)
5
Latest Filing Quarter
Q2 2026
New Institutional Positions
157
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 1.12% | 23,555,648 | $105,293,747 | $138,036,097 | +$32,742,350 | +31.10% | |
| Goldman Sachs Group Inc | 0.01% | 22,369,645 | $99,992,313 | $131,086,120 | +$31,093,807 | +31.10% | |
| Avoro Capital Advisors Llc | 0.96% | 21,700,000 | $96,999,000 | $127,162,000 | +$30,163,000 | +31.10% | |
| Blackrock, Inc. | 0.00% | 18,365,608 | $82,094,268 | $107,622,463 | +$25,528,195 | +31.10% | |
| Vestal Point Capital, Lp | 2.25% | 18,000,000 | $80,460,000 | $105,480,000 | +$25,020,000 | +31.10% | |
| Morgan Stanley | 0.00% | 17,965,371 | $80,305,209 | $105,277,074 | +$24,971,865 | +31.10% | |
| Fmr Llc | 0.00% | 14,321,255 | $64,016,010 | $83,922,554 | +$19,906,544 | +31.10% | |
| Rtw Investments, Lp | 0.61% | 13,680,248 | $61,150,709 | $80,166,253 | +$19,015,544 | +31.10% | |
| State Street Corp | 0.00% | 11,209,078 | $50,104,579 | $65,685,197 | +$15,580,618 | +31.10% | |
| Vanguard Capital Management Llc | 0.00% | 10,231,502 | $45,734,814 | $59,956,602 | +$14,221,788 | +31.10% | |
| Octagon Capital Advisors Lp | 4.38% | 8,859,911 | $39,603,802 | $51,919,078 | +$12,315,276 | +31.10% | |
| Siren, L.L.C. | 1.09% | 8,829,913 | $39,469,711 | $51,743,290 | +$12,273,579 | +31.10% | |
| Polar Capital Holdings Plc | 0.11% | 5,654,340 | $25,274,900 | $33,134,432 | +$7,859,532 | +31.10% | |
| Geode Capital Management, Llc | 0.00% | 5,531,955 | $24,732,183 | $32,417,256 | +$7,685,073 | +31.07% | |
| Gordonmd Global Investments Lp | 15.47% | 737,550 | $22,215,006 | $4,322,043 | -$17,892,963 | -80.54% | |
| D. E. Shaw & Co., Inc. | 0.02% | 4,427,301 | $19,790,035 | $25,943,984 | +$6,153,949 | +31.10% | |
| Baker Bros. Advisors Lp | 0.10% | 4,004,756 | $17,901,259 | $23,467,870 | +$5,566,611 | +31.10% | |
| Millennium Management Llc | 0.01% | 3,281,820 | $14,669,735 | $19,231,465 | +$4,561,730 | +31.10% | |
| Casdin Capital, Llc | 1.10% | 3,250,000 | $14,527,500 | $19,045,000 | +$4,517,500 | +31.10% | |
| Adar1 Capital Management, Llc | 0.80% | 2,979,429 | $13,318,048 | $17,459,454 | +$4,141,406 | +31.10% | |
| Healthcare Of Ontario Pension Plan Trust Fund | 0.02% | 2,883,301 | $12,888,355 | $16,896,144 | +$4,007,789 | +31.10% | |
| Deerfield Management Company, L.P. | 0.14% | 2,722,165 | $12,168,078 | $15,951,887 | +$3,783,809 | +31.10% | |
| Barclays Plc | 0.00% | 2,812,010 | $11,444,881 | $16,478,379 | +$5,033,498 | +43.98% | |
| Vanguard Portfolio Management Llc | 0.00% | 2,022,498 | $9,040,566 | $11,851,838 | +$2,811,272 | +31.10% | |
| Rice Hall James & Associates, Llc | 0.48% | 1,944,671 | $8,692,679 | $11,395,772 | +$2,703,093 | +31.10% | |
| Northern Trust Corp | 0.00% | 1,814,318 | $8,110,001 | $10,631,903 | +$2,521,902 | +31.10% | |
| Charles Schwab Investment Management Inc | 0.00% | 1,808,599 | $8,084,438 | $10,598,390 | +$2,513,952 | +31.10% | |
| B Group, Inc. | 5.97% | 1,800,556 | $8,048,485 | $10,551,258 | +$2,502,773 | +31.10% | |
| Bank Of America Corp | 0.00% | 1,677,046 | $7,496,395 | $9,827,490 | +$2,331,095 | +31.10% | |
| Vanguard Fiduciary Trust Co | 0.00% | 1,530,461 | $6,841,161 | $8,968,501 | +$2,127,340 | +31.10% | |
| Palo Alto Investors Lp | 0.95% | 1,391,382 | $6,219,478 | $8,153,499 | +$1,934,021 | +31.10% | |
| Aberdeen Group Plc | 0.01% | 1,021,063 | $4,564,152 | $5,983,429 | +$1,419,277 | +31.10% | |
| Affinity Asset Advisors, Llc | 0.26% | 1,000,000 | $4,470,000 | $5,860,000 | +$1,390,000 | +31.10% | |
| Granahan Investment Management, Llc | 0.19% | 883,241 | $3,948,087 | $5,175,792 | +$1,227,705 | +31.10% | |
| Affinity Wealth Management Llc | 0.51% | 576,808 | $3,928,062 | $3,380,095 | -$547,967 | -13.95% | |
| Quantum Private Wealth, Llc | 1.17% | 849,212 | $3,795,977 | $4,976,382 | +$1,180,405 | +31.10% | |
| Hennion & Walsh Asset Management, Inc. | 0.10% | 519,120 | $3,535,207 | $3,042,043 | -$493,164 | -13.95% | |
| Two Sigma Investments, Lp | 0.00% | 742,081 | $3,317,102 | $4,348,595 | +$1,031,493 | +31.10% | |
| Sands Capital Alternatives, Llc | 0.77% | 724,873 | $3,240,182 | $4,247,756 | +$1,007,574 | +31.10% | |
| Wellington Management Group Llp | 0.00% | 626,361 | $2,799,833 | $3,670,475 | +$870,642 | +31.10% | |
| Seven Fleet Capital Management Lp | 0.89% | 625,708 | $2,796,915 | $3,666,649 | +$869,734 | +31.10% | |
| Bank Of New York Mellon Corp | 0.00% | 608,123 | $2,718,311 | $3,563,601 | +$845,290 | +31.10% | |
| Nuveen, Llc | 0.00% | 549,153 | $2,454,714 | $3,218,037 | +$763,323 | +31.10% | |
| Ubs Group Ag | 0.00% | 517,698 | $2,314,110 | $3,033,710 | +$719,600 | +31.10% | |
| Woodline Partners Lp | 0.01% | 513,828 | $2,296,811 | $3,011,032 | +$714,221 | +31.10% | |
| Voya Investment Management Llc | 0.00% | 511,983 | $2,288,564 | $3,000,220 | +$711,656 | +31.10% | |
| Dimensional Fund Advisors Lp | 0.00% | 490,472 | $2,181,267 | $2,874,166 | +$692,899 | +31.77% | |
| Jefferies Financial Group Inc. | 0.03% | 479,000 | $2,141,130 | $2,806,940 | +$665,810 | +31.10% | |
| Point72 Asset Management, L.P. | 0.00% | 461,856 | $2,064,496 | $2,706,476 | +$641,980 | +31.10% | |
| Acuta Capital Partners, Llc | 1.40% | 439,464 | $1,964,404 | $2,575,259 | +$610,855 | +31.10% |
Frequently asked questions about TSHA
Who owns the most TSHA stock?
The largest holders of TSHA are typically major institutional investors such as asset managers and hedge funds reporting on Form 13F. The table above ranks tracked superinvestors by reported position size using the latest available filings for TAYSHA GENE THERAPIES INC (TSHA).
Is TSHA widely held by superinvestors?
Many widely followed stocks like TSHA appear across numerous superinvestor portfolios because of liquidity, index inclusion, and fundamentals. The holder count and table above show how broadly TSHA is represented among the institutional managers we track.
What do “Current Estimated Value”, “Gain/loss Since Filing”, and “Estimated Portfolio Performance” mean?
Current Estimated Value is reported share quantity from the latest 13F times our most recent split-adjusted U.S. session close. Gain/loss Since Filing is that estimate minus the reported 13F dollar value; Estimated Portfolio Performance is that difference as a percent of the reported value. Green means the estimate is above the filing value; red means below (not purchase cost). If many filers share the same implied filing price per share, the performance % may match across rows. These are not official fund marks or live quotes.