TYRA BIOSCIENCES INC (TYRA) Institutional Ownership Changes & 13F Activity
TYRA BIOSCIENCES INC (TYRA). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Price T Rowe Associates Inc, Hood River Capital Management Llc, Barclays Plc, Commodore Capital Lp, and Nextech Invest, Ltd..
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Manufacturers Life Insurance Company, The | Buy | +4,103 | +10.2% | 44,327 | $1.42M | Q2 2026 | Sep 09, 2026 |
| Citadel Advisors Llc | Buy | +262,911 | +1707.7% | 278,307 | $8.89M | Q2 2026 | Sep 02, 2026 |
| California State Teachers Retirement System | Buy | +23,142 | +1650.6% | 24,544 | $783.93K | Q2 2026 | Aug 24, 2026 |
| Public Employees Retirement System Of Ohio | Sell | -13,100 | -63.8% | 7,422 | $237.06K | Q2 2026 | Aug 17, 2026 |
| Capstone Investment Advisors, Llc | Buy | +10,051 | — | 10,051 | $321.03K | Q2 2026 | Aug 17, 2026 |
| Price T Rowe Associates Inc | Buy | +1,796,506 | +182.2% | 2,782,567 | $88.88M | Q2 2026 | Aug 14, 2026 |
| Hood River Capital Management Llc | Buy | +1,016,775 | — | 1,016,775 | $32.48M | Q2 2026 | Aug 14, 2026 |
| Barclays Plc | Sell | -813,124 | -97.6% | 20,275 | $647.59K | Q2 2026 | Aug 14, 2026 |
| Commodore Capital Lp | Sell | -600,000 | -24.2% | 1,875,000 | $59.89M | Q2 2026 | Aug 14, 2026 |
| Nextech Invest, Ltd. | Sell | -502,276 | -12.4% | 3,553,585 | $113.50M | Q2 2026 | Aug 14, 2026 |
| Bvf Inc/Il | Sell | -500,000 | -25.3% | 1,476,196 | $47.15M | Q2 2026 | Aug 14, 2026 |
| Caligan Partners Lp | Sell | -469,982 | -36.8% | 806,986 | $25.78M | Q2 2026 | Aug 14, 2026 |
| Deerfield Management Company, L.P. | Buy | +468,000 | +85.2% | 1,017,000 | $32.48M | Q2 2026 | Aug 14, 2026 |
| Stempoint Capital Lp | Buy | +439,577 | +227.6% | 632,754 | $20.21M | Q2 2026 | Aug 14, 2026 |
| Defilade Capital Management, L.P. | Buy | +376,870 | — | 376,870 | $12.04M | Q2 2026 | Aug 14, 2026 |
| Two Sigma Investments, Lp | Buy | +348,190 | +342.6% | 449,808 | $14.37M | Q2 2026 | Aug 14, 2026 |
| Elmind Capital, Lp | Sell | -330,000 | -94.3% | 20,000 | $638.80K | Q2 2026 | Aug 14, 2026 |
| Qube Research & Technologies Ltd | Buy | +266,934 | — | 266,934 | $8.53M | Q2 2026 | Aug 14, 2026 |
| Paradigm Biocapital Advisors Lp | Sell | -226,384 | -11.0% | 1,828,607 | $58.41M | Q2 2026 | Aug 14, 2026 |
| Sofinnova Investments, Inc. | Sell | -171,748 | -84.2% | 32,267 | $1.03M | Q2 2026 | Aug 14, 2026 |
| Adage Capital Partners Gp, L.L.C. | Buy | +162,000 | — | 162,000 | $5.17M | Q2 2026 | Aug 14, 2026 |
| Bank Of America Corp | Buy | +139,810 | +66.6% | 349,732 | $11.17M | Q2 2026 | Aug 14, 2026 |
| Lord, Abbett & Co. Llc | Buy | +121,833 | — | 121,833 | $3.89M | Q2 2026 | Aug 14, 2026 |
| Orbimed Advisors Llc | Buy | +102,000 | — | 102,000 | $3.26M | Q2 2026 | Aug 14, 2026 |
| Boothbay Fund Management, Llc | Sell | -99,715 | -36.5% | 173,559 | $5.54M | Q2 2026 | Aug 14, 2026 |
| Sio Capital Management, Llc | Buy | +89,876 | +14.8% | 695,315 | $22.21M | Q2 2026 | Aug 14, 2026 |
| Goldman Sachs Group Inc | Sell | -86,857 | -15.8% | 463,477 | $14.80M | Q2 2026 | Aug 14, 2026 |
| Jacobs Levy Equity Management, Inc | Sell | -72,999 | -45.0% | 89,205 | $2.85M | Q2 2026 | Aug 14, 2026 |
| Ensign Peak Advisors, Inc | Buy | +72,473 | +97.9% | 146,537 | $4.68M | Q2 2026 | Aug 14, 2026 |
| Charles Schwab Investment Management Inc | Buy | +68,588 | +34.4% | 267,699 | $8.55M | Q2 2026 | Aug 14, 2026 |
Frequently asked questions about TYRA activity
Which institutional owners are buying TYRA?
Institutional owners buying TYRA include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in TYRA activity?
"Buy" means an investor increased their reported position in TYRA compared to the prior reporting period. This reflects growing exposure to TYRA BIOSCIENCES INC (TYRA) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in TYRA increasing?
Institutional interest in TYRA can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
Related TYRA Institutional Insights
- TYRA Overview
- TYRA 13F Institutional Holders
- TYRA Top Institutional Shareholders
- Healthcare Sector Institutional Ownership
- Healthcare Sector Portfolio Overlap
- Institutional Portfolio Overlap & Shared Holdings
- Most Bought Healthcare Stocks By Institutional Investors
- Most Sold Healthcare Stocks By Institutional Investors
- TYRA Insider Trading & SEC Form 4 Activity
- TYRA Articles
- Top Institutional Investor Stock Rankings