LYELL IMMUNOPHARMA INC (LYEL) Institutional Ownership Changes & 13F Activity

LYELL IMMUNOPHARMA INC (LYEL). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Arch Venture Management, Llc, Foresite Capital Management Iv, Llc, Orland Properties Ltd, Almitas Capital Llc, and Foresite Capital Management V, Llc.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
Cornerstone Financial Management LlcBuy+46—46$1.42KQ4 2025Aug 28, 2026
Advisors Asset Management, Inc.Sell-567-100.0%0$0.00Q4 2025Aug 26, 2026
Ikarian Capital, LlcBuy+41,081—41,081$1.26MQ4 2025Feb 18, 2026
Raymond James Financial IncBuy+7,900—7,900$243.16KQ4 2025Feb 18, 2026
Arch Venture Management, LlcBuy+2,759,072—2,759,072$84.92MQ4 2025Feb 17, 2026
Foresite Capital Management Iv, LlcBuy+800,399—800,399$24.64MQ4 2025Feb 17, 2026
Orland Properties LtdBuy+754,698—754,698$23.23MQ4 2025Feb 17, 2026
Almitas Capital LlcBuy+577,807—577,807$17.78MQ4 2025Feb 17, 2026
Foresite Capital Management V, LlcBuy+477,078—477,078$14.68MQ4 2025Feb 17, 2026
Venbio Partners LlcBuy+337,697—337,697$10.39MQ4 2025Feb 17, 2026
Citadel Advisors LlcBuy+324,701—324,701$9.99MQ4 2025Feb 17, 2026
Susquehanna International Group, LlpBuy+151,016—151,016$4.65MQ4 2025Feb 17, 2026
Mic Capital Management Uk LlpBuy+87,028—87,028$2.68MQ4 2025Feb 17, 2026
Rbf Capital, LlcBuy+74,585—74,585$2.30MQ4 2025Feb 17, 2026
Millennium Management LlcBuy+58,651—58,651$1.81MQ4 2025Feb 17, 2026
Canada Pension Plan Investment BoardBuy+32,111—32,111$988.38KQ4 2025Feb 17, 2026
Northern Trust CorpBuy+30,280—30,280$932.02KQ4 2025Feb 17, 2026
Susquehanna Portfolio Strategies, LlcBuy+20,800—20,800$640.22KQ4 2025Feb 17, 2026
Bridgeway Capital Management, LlcBuy+18,000—18,000$554.04KQ4 2025Feb 17, 2026
Two Sigma Investments, LpBuy+15,616—15,616$480.66KQ4 2025Feb 17, 2026
Price T Rowe Associates IncBuy+13,128—13,128$405.00KQ4 2025Feb 17, 2026
Point72 Asset Management, L.P.Buy+11,480—11,480$353.35KQ4 2025Feb 17, 2026
Boothbay Fund Management, LlcBuy+9,516—9,516$292.90KQ4 2025Feb 17, 2026
Qube Research & Technologies LtdBuy+9,051—9,051$278.59KQ4 2025Feb 17, 2026
Exoduspoint Capital Management, LpBuy+8,511—8,511$261.97KQ4 2025Feb 17, 2026
Bank Of America CorpBuy+8,045—8,045$247.63KQ4 2025Feb 17, 2026
Fmr LlcBuy+1,829—1,829$56.30KQ4 2025Feb 17, 2026
Tower Research Capital Llc (Trc)Buy+1,194—1,194$36.75KQ4 2025Feb 17, 2026
Jones Financial Companies LllpBuy+1,025—1,025$31.55KQ4 2025Feb 17, 2026
Osaic Holdings, Inc.Buy+124—124$3.82KQ4 2025Feb 17, 2026
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Frequently asked questions about LYEL activity

  • Which institutional owners are buying LYEL?

    Institutional owners buying LYEL include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in LYEL activity?

    "Buy" means an investor increased their reported position in LYEL compared to the prior reporting period. This reflects growing exposure to LYELL IMMUNOPHARMA INC (LYEL) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in LYEL increasing?

    Institutional interest in LYEL can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.