MBX Institutional Ownership & Shareholders
MBX Biosciences, Inc. (MBX) is currently held by 173 institutional investors tracked by InsiderSet, with a combined reported market value of approximately $3.05B based on the latest available SEC Form 13F filings for the quarter ended June 30, 2026.
Frazier Life Sciences Management, L.P. is currently the largest disclosed institutional shareholder of MBX tracked by InsiderSet, reporting ownership valued at approximately $367.19M in its June 30, 2026 SEC Form 13F filing. Based on current market prices and the latest disclosed share count, the position is now estimated to be worth approximately $371.65M, representing an estimated gain of +1.21% since the filing period.
The top 10 institutional shareholders tracked on this page collectively account for approximately 64% of the total disclosed MBX value among the investors covered in this analysis. Major shareholders include Frazier Life Sciences Management, L.P., Fmr Llc, Wellington Management Group Llp, and several other long-term asset managers with concentrated positions in MBX Biosciences, Inc. (MBX).
This page ranks the largest institutional MBX shareholders using publicly disclosed SEC Form 13F data, including reported values, estimated current holding values, portfolio allocation percentages, ownership concentration metrics, and historical holding changes across major hedge funds and investment firms.
Institutional Holders
173
Total Reported Value
$3.05B
Largest Holder
Frazier Life Sciences Management, L.P.
Largest Position
$367.19M
Insider Transactions (90d)
0
Latest Filing Quarter
Q2 2026
New Institutional Positions
71
Funds Exiting Positions
0
| Name | Investor/Manager | Portfolio % | Quantity | Reported Balance | Current Estimated Value | Gain/loss Since Filing | Estimated Portfolio Performance |
|---|---|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | 8.00% | 6,652,013 | $367,191,118 | $371,647,966 | +$4,456,848 | +1.21% | |
| Fmr Llc | 0.01% | 5,322,885 | $293,823,234 | $297,389,585 | +$3,566,351 | +1.21% | |
| Wellington Management Group Llp | 0.05% | 4,977,523 | $274,759,269 | $278,094,210 | +$3,334,941 | +1.21% | |
| Nea Management Company, Llc | 12.56% | 3,614,486 | $199,519,627 | $201,941,333 | +$2,421,706 | +1.21% | |
| Orbimed Advisors Llc | 3.58% | 3,428,736 | $189,266,227 | $191,563,480 | +$2,297,253 | +1.21% | |
| Blackrock, Inc. | 0.00% | 3,323,672 | $183,466,695 | $185,693,555 | +$2,226,860 | +1.21% | |
| Paradigm Biocapital Advisors Lp | 2.59% | 2,508,015 | $138,442,428 | $140,122,798 | +$1,680,370 | +1.21% | |
| Nvp Associates, Llc | 35.93% | 2,136,335 | $117,925,692 | $119,357,036 | +$1,431,344 | +1.21% | |
| Deep Track Capital, Lp | 1.41% | 1,732,569 | $95,637,809 | $96,798,630 | +$1,160,821 | +1.21% | |
| Polar Capital Holdings Plc | 0.25% | 1,608,514 | $88,789,973 | $89,867,677 | +$1,077,704 | +1.21% | |
| Vanguard Capital Management Llc | 0.00% | 1,477,388 | $81,551,818 | $82,541,668 | +$989,850 | +1.21% | |
| Aaron Wealth Advisors Llc | 3.37% | 1,175,771 | $68,923,696 | $65,690,326 | -$3,233,370 | -4.69% | |
| Driehaus Capital Management Llc | 0.34% | 1,056,579 | $58,323,161 | $59,031,069 | +$707,908 | +1.21% | |
| Kynam Capital Management, Lp | 2.85% | 934,799 | $51,600,905 | $52,227,220 | +$626,315 | +1.21% | |
| Woodline Partners Lp | 0.15% | 900,092 | $49,685,078 | $50,288,140 | +$603,062 | +1.21% | |
| Eventide Asset Management, Llc | 0.64% | 873,492 | $48,216,758 | $48,801,998 | +$585,240 | +1.21% | |
| State Street Corp | 0.00% | 864,466 | $47,718,523 | $48,297,715 | +$579,192 | +1.21% | |
| Price T Rowe Associates Inc | 0.00% | 814,807 | $44,978,000 | $45,523,267 | +$545,267 | +1.21% | |
| Parkman Healthcare Partners Llc | 4.54% | 800,173 | $44,169,550 | $44,705,666 | +$536,116 | +1.21% | |
| Geode Capital Management, Llc | 0.00% | 773,072 | $42,683,039 | $43,191,533 | +$508,494 | +1.19% | |
| Braidwell Lp | 1.45% | 710,880 | $39,240,576 | $39,716,866 | +$476,290 | +1.21% | |
| Tcg Crossover Management, Llc | 0.86% | 650,000 | $35,880,000 | $36,315,500 | +$435,500 | +1.21% | |
| Cormorant Asset Management, Lp | 1.56% | 550,000 | $30,360,000 | $30,728,500 | +$368,500 | +1.21% | |
| Soleus Capital Management, L.P. | 0.98% | 515,279 | $28,443,401 | $28,788,638 | +$345,237 | +1.21% | |
| Goldman Sachs Group Inc | 0.00% | 459,005 | $25,337,076 | $25,644,609 | +$307,533 | +1.21% | |
| Marshall Wace, Llp | 0.02% | 401,885 | $22,184,052 | $22,453,315 | +$269,263 | +1.21% | |
| Ecor1 Capital, Llc | 1.06% | 388,500 | $21,445,200 | $21,705,495 | +$260,295 | +1.21% | |
| Vanguard Portfolio Management Llc | 0.00% | 346,717 | $19,138,778 | $19,371,079 | +$232,301 | +1.21% | |
| Bank Of America Corp | 0.00% | 298,927 | $16,500,771 | $16,701,051 | +$200,280 | +1.21% | |
| Rock Springs Capital Management Lp | 0.80% | 298,218 | $16,461,634 | $16,661,440 | +$199,806 | +1.21% | |
| Candriam S.C.A. | 0.07% | 289,893 | $15,986,698 | $16,196,322 | +$209,624 | +1.31% | |
| Ubs Group Ag | 0.00% | 272,747 | $15,055,635 | $15,238,375 | +$182,740 | +1.21% | |
| Opaleye Management Inc. | 1.30% | 260,000 | $14,352,000 | $14,526,200 | +$174,200 | +1.21% | |
| Schonfeld Strategic Advisors Llc | 0.07% | 248,670 | $13,726,583 | $13,893,193 | +$166,610 | +1.21% | |
| Morgan Stanley | 0.00% | 248,558 | $13,720,403 | $13,886,935 | +$166,532 | +1.21% | |
| Northern Trust Corp | 0.00% | 246,678 | $13,616,626 | $13,781,900 | +$165,274 | +1.21% | |
| Dimensional Fund Advisors Lp | 0.00% | 233,700 | $12,900,240 | $13,056,819 | +$156,579 | +1.21% | |
| Charles Schwab Investment Management Inc | 0.00% | 233,095 | $12,866,844 | $13,023,018 | +$156,174 | +1.21% | |
| Millennium Management Llc | 0.01% | 226,151 | $12,483,535 | $12,635,056 | +$151,521 | +1.21% | |
| Tetragon Partners Gp Ltd | 1.83% | 203,543 | $11,235,574 | $11,371,947 | +$136,373 | +1.21% | |
| Vanguard Fiduciary Trust Co | 0.00% | 201,429 | $11,118,881 | $11,253,838 | +$134,957 | +1.21% | |
| Caligan Partners Lp | 0.53% | 200,000 | $11,040,000 | $11,174,000 | +$134,000 | +1.21% | |
| D. E. Shaw & Co., Inc. | 0.01% | 182,767 | $10,088,738 | $10,211,192 | +$122,454 | +1.21% | |
| Jpmorgan Chase & Co | 0.00% | 139,611 | $7,518,053 | $7,800,067 | +$282,014 | +3.75% | |
| Kvp Capital Advisors, Lp | 4.92% | 121,524 | $6,708,125 | $6,789,546 | +$81,421 | +1.21% | |
| Two Sigma Investments, Lp | 0.00% | 113,475 | $6,263,820 | $6,339,848 | +$76,028 | +1.21% | |
| Burkehill Global Management, Lp | 0.20% | 100,000 | $5,520,000 | $5,587,000 | +$67,000 | +1.21% | |
| Nuveen, Llc | 0.00% | 98,733 | $5,450,062 | $5,516,213 | +$66,151 | +1.21% | |
| Td Asset Management Inc | 0.00% | 95,598 | $5,277,010 | $5,341,060 | +$64,050 | +1.21% | |
| Elmind Capital, Lp | 1.26% | 91,000 | $5,023,200 | $5,084,170 | +$60,970 | +1.21% |
Frequently asked questions about MBX
Who are the largest institutional holders of MBX?
The largest institutional holders of MBX reported in the latest SEC Form 13F filings include Frazier Life Sciences Management, L.P., Fmr Llc, Wellington Management Group Llp, Nea Management Company, Llc, and Orbimed Advisors Llc. InsiderSet ranks institutional holders by their latest reported MBX position.
What is MBX institutional ownership?
This page tracks MBX positions reported by institutional investment managers through SEC Form 13F. MBX Biosciences, Inc. (MBX) institutional ownership on InsiderSet reflects disclosed 13F holdings among the managers we analyze, not every shareholder of the stock.
How many institutions own MBX?
InsiderSet currently tracks 173 institutional managers reporting MBX holdings in the latest available 13F data. This count reflects institutions included in the SEC Form 13F filings analyzed by InsiderSet and should not be interpreted as the total number of MBX shareholders.
How much MBX stock do institutions own?
Institutional investment managers disclosed approximately $3.05B in MBX holdings for Q2 2026. This figure is reported 13F value as of the filing period, not necessarily today's market value.
When was MBX institutional ownership last updated?
The latest MBX institutional ownership data on InsiderSet is based on SEC Form 13F filings for the quarter ended June 30, 2026. Form 13F filings are generally reported after the quarter ends, so the holdings shown represent the latest publicly disclosed positions rather than real-time institutional holdings.
Are institutional MBX holdings real-time?
No. Form 13F data is not real-time. It represents positions reported by institutional investment managers as of the end of the reporting quarter. An institution may have changed its MBX position after the reporting date.
Are institutions buying or selling MBX?
Institutional buying and selling can be analyzed by comparing MBX positions across consecutive 13F reporting periods. InsiderSet's MBX Ownership Changes page shows institutions that increased, reduced, initiated, or exited positions based on reported 13F holdings. View MBX ownership changes.
How has MBX institutional ownership changed over time?
InsiderSet tracks MBX institutional holdings across multiple 13F reporting periods, allowing investors to compare institutional holder counts, reported value, and reported shares over time.