ORCHESTRA BIOMED HOLDINGS IN (OBIO) Institutional Ownership Changes & 13F Activity

ORCHESTRA BIOMED HOLDINGS IN (OBIO). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q2 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Rtw Investments, Lp, Affinity Asset Advisors, Llc, State Street Corp, Ubs Group Ag, and Vanguard Portfolio Management Llc.

InstitutionTypeChange in sharesChange Position %SharesReported stock balancePortfolio quarterFiling date
State Street CorpBuy+346,640+204.6%516,050$2.23MQ2 2026Sep 22, 2026
Citadel Advisors LlcSell-22,994-29.0%56,191$242.46KQ2 2026Sep 02, 2026
California State Teachers Retirement SystemBuy+549—549$2.37KQ2 2026Aug 24, 2026
Rtw Investments, LpBuy+1,250,000+15.0%9,556,063$41.23MQ2 2026Aug 14, 2026
Flat Footed LlcBuy+251,372—251,372$1.08MQ2 2026Aug 14, 2026
Charles Schwab Investment Management IncBuy+84,045+31.7%349,544$1.51MQ2 2026Aug 14, 2026
Barclays PlcSell-45,824-77.2%13,518$58.33KQ2 2026Aug 14, 2026
Jane Street Group, LlcSell-40,320-72.4%15,360$66.28KQ2 2026Aug 14, 2026
Xtx Topco LtdBuy+38,814—38,814$167.48KQ2 2026Aug 14, 2026
Two Sigma Investments, LpSell-37,544-62.5%22,563$97.36KQ2 2026Aug 14, 2026
Wells Fargo & Company/MnBuy+36,356—36,356$156.88KQ2 2026Aug 14, 2026
Price T Rowe Associates IncBuy+32,689—32,689$142.00KQ2 2026Aug 14, 2026
Susquehanna International Group, LlpSell-31,717-32.5%65,804$283.94KQ2 2026Aug 14, 2026
Bank Of America CorpSell-28,939-54.8%23,822$102.79KQ2 2026Aug 14, 2026
Invesco Ltd.Buy+24,689—24,689$106.53KQ2 2026Aug 14, 2026
Goldman Sachs Group IncBuy+24,364+15.7%179,606$775.00KQ2 2026Aug 14, 2026
Metlife Investment Management, LlcBuy+23,994—23,994$103.53KQ2 2026Aug 14, 2026
Mirae Asset Global Etfs Holdings Ltd.Buy+18,352—18,352$79.19KQ2 2026Aug 14, 2026
Bridgeway Capital Management, LlcBuy+10,000+14.2%80,600$347.79KQ2 2026Aug 14, 2026
Canada Pension Plan Investment BoardBuy+9,800+86.7%21,100$91.05KQ2 2026Aug 14, 2026
Legal & General Group PlcBuy+3,924—3,924$16.93KQ2 2026Aug 14, 2026
Royal Bank Of CanadaBuy+928+99.1%1,864$8.00KQ2 2026Aug 14, 2026
Jones Financial Companies LllpBuy+500+128.9%888$3.77KQ2 2026Aug 14, 2026
Affinity Asset Advisors, LlcSell-369,150-91.7%33,400$144.12KQ2 2026Aug 13, 2026
Ubs Group AgBuy+275,463+547.5%325,773$1.41MQ2 2026Aug 13, 2026
Vanguard Portfolio Management LlcBuy+274,973—274,973$1.19MQ2 2026Aug 13, 2026
Northern Trust CorpBuy+225,366+190.5%343,640$1.48MQ2 2026Aug 13, 2026
Vanguard Capital Management LlcSell-181,403-8.2%2,022,916$8.73MQ2 2026Aug 13, 2026
Vanguard Fiduciary Trust CoBuy+57,039+24.2%292,253$1.26MQ2 2026Aug 13, 2026
Renaissance Technologies LLCBuy+19,100+26.9%90,000$388.35KQ2 2026Aug 13, 2026
Showing 30 of 74

Frequently asked questions about OBIO activity

  • Which institutional owners are buying OBIO?

    Institutional owners buying OBIO include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in OBIO activity?

    "Buy" means an investor increased their reported position in OBIO compared to the prior reporting period. This reflects growing exposure to ORCHESTRA BIOMED HOLDINGS IN (OBIO) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in OBIO increasing?

    Institutional interest in OBIO can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.