STRUCTURE THERAPEUTICS INC (GPCR) Institutional Ownership Changes & 13F Activity
STRUCTURE THERAPEUTICS INC (GPCR). Institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC Form 13F filings (Q4 2025). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions in the latest reporting period. Notable filers include Fmr Llc, Wellington Management Group Llp, Avoro Capital Advisors Llc, Janus Henderson Group Plc, and Bvf Inc/Il.
| Institution | Type | Change in shares | Change Position % | Shares | Reported stock balance | Portfolio quarter | Filing date |
|---|---|---|---|---|---|---|---|
| Catalio Capital Management, Lp | Buy | +252,901 | — | 252,901 | $17.59M | Q4 2025 | Sep 02, 2026 |
| Flax Pond Capital, Llc | Buy | +48,721 | — | 48,721 | $3.39M | Q4 2025 | Mar 09, 2026 |
| Shp Wealth Management | Buy | +100 | — | 100 | $6.96K | Q4 2025 | Mar 04, 2026 |
| Raymond James Financial Inc | Buy | +44,388 | — | 44,388 | $3.09M | Q4 2025 | Feb 18, 2026 |
| Ikarian Capital, Llc | Buy | +4,824 | — | 4,824 | $335.51K | Q4 2025 | Feb 18, 2026 |
| Fmr Llc | Buy | +8,712,251 | — | 8,712,251 | $605.94M | Q4 2025 | Feb 17, 2026 |
| Wellington Management Group Llp | Buy | +7,121,984 | — | 7,121,984 | $495.33M | Q4 2025 | Feb 17, 2026 |
| Avoro Capital Advisors Llc | Buy | +6,555,555 | — | 6,555,555 | $455.94M | Q4 2025 | Feb 17, 2026 |
| Janus Henderson Group Plc | Buy | +5,090,148 | — | 5,090,148 | $354.01M | Q4 2025 | Feb 17, 2026 |
| Bvf Inc/Il | Buy | +3,479,022 | — | 3,479,022 | $241.97M | Q4 2025 | Feb 17, 2026 |
| Price T Rowe Associates Inc | Buy | +1,671,138 | — | 1,671,138 | $116.23M | Q4 2025 | Feb 17, 2026 |
| Driehaus Capital Management Llc | Buy | +1,642,444 | — | 1,642,444 | $114.23M | Q4 2025 | Feb 17, 2026 |
| Baker Bros. Advisors Lp | Buy | +1,432,529 | — | 1,432,529 | $99.63M | Q4 2025 | Feb 17, 2026 |
| Casdin Capital, Llc | Buy | +1,175,000 | — | 1,175,000 | $81.72M | Q4 2025 | Feb 17, 2026 |
| Orbimed Advisors Llc | Buy | +1,161,803 | — | 1,161,803 | $80.80M | Q4 2025 | Feb 17, 2026 |
| Tcg Crossover Management, Llc | Buy | +920,857 | — | 920,857 | $64.05M | Q4 2025 | Feb 17, 2026 |
| Capitolis Liquid Global Markets Llc | Buy | +878,300 | — | 878,300 | $61.09M | Q4 2025 | Feb 17, 2026 |
| Alliancebernstein L.P. | Buy | +848,851 | — | 848,851 | $59.04M | Q4 2025 | Feb 17, 2026 |
| Citadel Advisors Llc | Buy | +772,518 | — | 772,518 | $53.73M | Q4 2025 | Feb 17, 2026 |
| Deerfield Management Company, L.P. | Buy | +767,993 | — | 767,993 | $53.41M | Q4 2025 | Feb 17, 2026 |
| Rock Springs Capital Management Lp | Buy | +748,236 | — | 748,236 | $52.04M | Q4 2025 | Feb 17, 2026 |
| Logos Global Management Lp | Buy | +600,000 | — | 600,000 | $41.73M | Q4 2025 | Feb 17, 2026 |
| Stempoint Capital Lp | Buy | +351,073 | — | 351,073 | $24.42M | Q4 2025 | Feb 17, 2026 |
| Ecor1 Capital, Llc | Buy | +334,380 | — | 334,380 | $23.26M | Q4 2025 | Feb 17, 2026 |
| Ameriprise Financial Inc | Buy | +285,518 | — | 285,518 | $19.86M | Q4 2025 | Feb 17, 2026 |
| Arrowmark Colorado Holdings Llc | Buy | +271,213 | — | 271,213 | $18.86M | Q4 2025 | Feb 17, 2026 |
| National Bank Of Canada | Buy | +265,400 | — | 265,400 | $18.46M | Q4 2025 | Feb 17, 2026 |
| Voloridge Investment Management, Llc | Buy | +250,000 | — | 250,000 | $17.39M | Q4 2025 | Feb 17, 2026 |
| Balyasny Asset Management L.P. | Buy | +216,199 | — | 216,199 | $15.04M | Q4 2025 | Feb 17, 2026 |
| Sio Capital Management, Llc | Buy | +201,500 | — | 201,500 | $14.01M | Q4 2025 | Feb 17, 2026 |
Frequently asked questions about GPCR activity
Which institutional owners are buying GPCR?
Institutional owners buying GPCR include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.
What does "buy" mean in GPCR activity?
"Buy" means an investor increased their reported position in GPCR compared to the prior reporting period. This reflects growing exposure to STRUCTURE THERAPEUTICS INC (GPCR) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).
Is institutional interest in GPCR increasing?
Institutional interest in GPCR can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.
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