VERTEX PHARMACEUTICALS INC (VRTX) Institutional Ownership Changes & 13F Activity

VERTEX PHARMACEUTICALS INC (VRTX) institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC 13F filings (Q1 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions among tracked filers. Notable filers include Renaissance Technologies LLC, Sequoia Financial Advisors, Tweedy, Browne Co All Funds (US), Torray Fund, and ARK Invest.

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q2 2021Renaissance Technologies LLCSell-123,0002,277,284$459,169
Q2 2021ARK InvestBuy55,0201,774,066$357,705
Q1 2021Renaissance Technologies LLCSell-1,175,6462,400,284$515,797
Q1 2021ARK InvestBuy902,8521,719,046$369,406
Q4 2020Renaissance Technologies LLCSell-1,631,0023,575,930$845,135
Q4 2020ARK InvestBuy718,842816,194$192,899
Q3 2020Renaissance Technologies LLCSell-574,4005,206,932$1,416,910
Q3 2020ARK InvestBuy97,35297,352$26,491
Q2 2020Renaissance Technologies LLCSell-1,078,3505,781,332$1,678,378
Q1 2020Renaissance Technologies LLCSell-216,9006,859,682$1,632,261
Q4 2019Renaissance Technologies LLCBuy1,277,4657,076,582$1,549,418
Q3 2019Renaissance Technologies LLCBuy243,3005,799,117$982,486
Q2 2019Renaissance Technologies LLCBuy477,1005,555,817$1,018,826
Q1 2019Renaissance Technologies LLCBuy744,4175,078,717$934,230
Q4 2018Renaissance Technologies LLCBuy245,1834,334,300$718,237
Q3 2018Renaissance Technologies LLCBuy1,238,2004,089,117$788,136
Q1 2018Renaissance Technologies LLCBuy3,0002,850,917$464,642
Q4 2017Renaissance Technologies LLCBuy1,479,8972,847,917$426,789
Q3 2017Renaissance Technologies LLCBuy1,346,3201,368,020$207,994
Q2 2017Renaissance Technologies LLCSell-18,41721,700$2,796
Q1 2017Renaissance Technologies LLCSell-20,40040,117$4,387
Q2 2016Renaissance Technologies LLCSell-52,10060,517$5,206
Q1 2016Renaissance Technologies LLCBuy51,300112,617$8,952
Q4 2015Renaissance Technologies LLCSell-98,00061,317$7,716
Q4 2015Viking Global InvestorsBuy77,2091,421,673$178,889
Q3 2015Viking Global InvestorsSell-460,7221,344,464$140,012
Q2 2015Viking Global InvestorsBuy35,0361,805,186$222,904
Q1 2015Viking Global InvestorsBuy1,005,9501,770,150$208,825
Q1 2015Renaissance Technologies LLCSell-152,847159,317$18,795
Q4 2014Viking Global InvestorsBuy764,200764,200$90,787

Frequently asked questions about VRTX activity

  • Which institutional owners are buying VRTX?

    Institutional owners buying VRTX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in VRTX activity?

    "Buy" means an investor increased their reported position in VRTX compared to the prior reporting period. This reflects growing exposure to VERTEX PHARMACEUTICALS INC (VRTX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in VRTX increasing?

    Institutional interest in VRTX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.

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