VERTEX PHARMACEUTICALS INC (VRTX) Institutional Ownership Changes & 13F Activity

VERTEX PHARMACEUTICALS INC (VRTX) institutional ownership data tracks hedge funds, asset managers, and other institutional investors based on recent SEC 13F filings (Q1 2026). This page analyzes institutional buying and selling activity, new holdings, and sold-out positions among tracked filers. Notable filers include Renaissance Technologies LLC, Sequoia Financial Advisors, Tweedy, Browne Co All Funds (US), Torray Fund, and ARK Invest.

Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q3 2023Parnassus Endeavor FundBuy50664$230,899
Q2 2023Renaissance Technologies LLCSell-125,5741,272,161$447,686
Q2 2023ARK InvestSell-4,838115,671$40,705,957
Q2 2023Mairs & Power Growth FundBuy655655$230,501
Q2 2023Sequoia Financial AdvisorsBuy2602,729$960,363
Q2 2023Parnassus Endeavor FundSell-152614$216,073
Q1 2023Renaissance Technologies LLCSell-849,0171,397,735$440,384
Q1 2023Parnassus Endeavor FundSell-239,515766$241,344
Q1 2023ARK InvestSell-1,688120,509$37,968,771
Q1 2023Sequoia Financial AdvisorsBuy1102,469$777,908
Q4 2022Renaissance Technologies LLCBuy107,8672,246,752$648,817
Q4 2022ARK InvestSell-35,248122,197$35,288,050
Q4 2022Parnassus Endeavor FundSell-21,686240,281$69,388,347
Q4 2022Sequoia Financial AdvisorsBuy1,3992,359$681,210
Q3 2022Renaissance Technologies LLCBuy377,7172,138,885$619,293
Q3 2022ARK InvestSell-208,077157,445$45,587
Q3 2022Sequoia Financial AdvisorsBuy20960$278
Q2 2022Parnassus Endeavor FundSell-309,518261,967$73,820
Q2 2022ARK InvestSell-56,253365,522$98,197
Q2 2022Renaissance Technologies LLCBuy53,8001,761,168$496,280
Q2 2022Sequoia Financial AdvisorsBuy940940$265
Q1 2022ARK InvestSell-507,016421,775$110,071
Q1 2022Renaissance Technologies LLCBuy80,5001,707,368$445,572
Q1 2022Parnassus Endeavor FundSell-47,953571,485$149,140
Q4 2021ARK InvestSell-780,960928,791$203,963
Q4 2021Renaissance Technologies LLCSell-264,6181,626,868$357,260
Q4 2021Hancock Classic ValueBuy2,9052,905$638
Q3 2021Renaissance Technologies LLCSell-385,7981,891,486$343,097
Q3 2021ARK InvestSell-64,3151,709,751$310,132
Q2 2021Parnassus Endeavor FundBuy619,438619,438$124,897

Frequently asked questions about VRTX activity

  • Which institutional owners are buying VRTX?

    Institutional owners buying VRTX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in VRTX activity?

    "Buy" means an investor increased their reported position in VRTX compared to the prior reporting period. This reflects growing exposure to VERTEX PHARMACEUTICALS INC (VRTX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in VRTX increasing?

    Institutional interest in VRTX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.

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