VERTEX PHARMACEUTICALS INC (VRTX) Stock Institutional Trading Activity


VERTEX PHARMACEUTICALS INC (VRTX) position changes reported by tracked institutional filers across multiple SEC 13F reporting periods. Based on recent SEC 13F filings (Q4 2025), investors with some of the largest reported share count changes include Renaissance Technologies LLC, Tweedy, Browne Co All Funds (US), Parnassus Endeavor Fund, ARK Invest, and Torray Fund. Explore insights into buying and selling patterns, position changes, and investment conviction levels to understand institutional trading behavior and market dynamics.

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Portfolio quarterNameTypeQuantityRemainingReported stock balance
Q3 2024Egerton Capital UKBuy124,045124,045$57,690,849
Q3 2024Renaissance Technologies LLCBuy65,1051,631,493$758,774,764
Q2 2024Torray FundSell-9,76413,938$6,533,019
Q2 2024Tweedy, Browne Co All Funds (US)Sell-12,35354,346$25,473,057
Q2 2024ARK InvestSell-14,64075,464$35,371,352
Q2 2024Sequoia Financial AdvisorsBuy33411,141$5,222,215
Q2 2024Renaissance Technologies LLCSell-14,1001,566,388$734,197,383
Q1 2024Torray FundBuy9,63423,702$5,809,921
Q1 2024Tweedy, Browne Co All Funds (US)Sell-6566,699$27,880,849
Q1 2024ARK InvestSell-34,09390,104$37,664,348
Q1 2024Renaissance Technologies LLCSell-11,2001,580,488$660,660
Q1 2024Sequoia Financial AdvisorsSell-3,56910,807$4,517,617
Q4 2023Torray FundSell-62,32914,068$5,724,129
Q4 2023Tweedy, Browne Co All Funds (US)Sell-8,24066,764$27,165,604
Q4 2023ARK InvestBuy8,866124,197$50,534,538
Q4 2023Parnassus Endeavor FundBuy74738$300,285
Q4 2023Renaissance Technologies LLCSell-72,4001,591,688$647,642
Q4 2023Sequoia Financial AdvisorsBuy11,44814,376$5,849,316
Q3 2023Tweedy, Browne Co All Funds (US)Buy75,00475,004$26,081,891
Q3 2023ARK InvestSell-340115,331$40,105,107
Q3 2023Parnassus Endeavor FundBuy50664$230,899
Q3 2023Mairs & Power Growth FundBuy100755$262,544
Q3 2023Renaissance Technologies LLCBuy391,9271,664,088$578,670
Q3 2023Sequoia Financial AdvisorsBuy1992,928$1,018,332
Q2 2023ARK InvestSell-4,838115,671$40,705,957
Q2 2023Parnassus Endeavor FundSell-152614$216,073
Q2 2023Mairs & Power Growth FundBuy655655$230,501
Q2 2023Renaissance Technologies LLCSell-125,5741,272,161$447,686
Q2 2023Sequoia Financial AdvisorsBuy2602,729$960,363
Q1 2023ARK InvestSell-1,688120,509$37,968,771

Frequently asked questions about VRTX activity

  • Which institutional owners are buying VRTX?

    Institutional owners buying VRTX include investors who have either initiated new positions or increased their existing holdings based on recent SEC 13F filings. The activity table above highlights which funds added shares in the latest reporting periods and how their positions changed over time.

  • What does "buy" mean in VRTX activity?

    "Buy" means an investor increased their reported position in VRTX compared to the prior reporting period. This reflects growing exposure to VERTEX PHARMACEUTICALS INC (VRTX) rather than necessarily a brand-new position (though new positions also appear as buys when prior quantity was zero).

  • Is institutional interest in VRTX increasing?

    Institutional interest in VRTX can be assessed by comparing the number of tracked funds adding or increasing positions versus those trimming or exiting across the periods shown. A higher number of additions typically signals increasing participation among large filers, but it should be read alongside position sizes and the full table.